Thermo Scientific Microm HM550 cryostat

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1 With gold standard disinfection in 3 minutes Thermo Scientific Microm HM550 cryostat Safety Part of Thermo Fisher Scientific Ergonomics Quality Precision

2 Avoid the risk of occupational infections with the new gold standard cold disinfection in cryostats Every year, tens of thousands of healthcare workers suffer from occupational infections, such as HBV, HCV and HIV. Their risk of catching these infections is significantly higher than in the average population. Working with infectious material is inherent to work in pathology laboratories, which is why it is our goal to minimize any health hazards. With enhanced safety and efficiency in mind, the new patented cold disinfection solution is being introduced as standard with the Thermo Scientific Microm HM550. Cold disinfection from Thermo Scientific offers customers instant disinfection, significantly reducing risks to the occupational health of laboratory staff. Outstanding advantages Ready for use in just three minutes no workflow interruption Immediately available for use after disinfection cycle Utilizes Sanosil, a powerful nonhazardous disinfectant completely safe for lab technicians The keys to a new gold standard Instant disinfection of the entire cold cryo-chamber 100 times faster than existing methods Fumigation of disinfection by ultrasound instrument is immediately available for use, resulting in significantly higher throughput Micro-droplets uniformly moisten the entire cryo-chamber Sanosil no need to be toxic to be effective A disinfectant and virucide that harnesses the natural, antimicrobial powers of Hydrogen Peroxide and Silver (Ag + ) The combination of these two elements provides pure, 99.99% disinfecting power Contains NO chlorine, aldehydes, phenolics, ammonium compounds, sodium hydroxide or any other harmful toxins or carcinogens Clear and odorless

3 Perfect results quickly and safely whilst meeting the highest standards for hygiene. Ready for safe operation in just 3 minutes. Create and maintain a safe and germ-free working environment. Thermo Scientific Microm HM550 is now equipped with the new cold disinfection feature. Hygiene and cleanliness of your cryo-chamber is now assured with no compromise. Enjoy a fully flexible system created with safety, precision and flexibility in mind. Snap freezing via active deep freezing device Integrated Peltier: fast freezing of the tissue at a temperature down to -60 C Offers four positions for chucks with a diameter up to 30 mm The 9 position fast freezing rail provides temperature control down to -40 C Perfect specimen orientation 0-positioning device automatically locks the specimen orientation into place Fast automatic approach of the tissue towards the knife edge (ACA) Ergonomics, safety and design Fully adjustable electronic handwheel brake in any specimen position Designed to be operated while sitting or standing Keyboard and display intuitively guide through all operations Reflex-free chamber illumination Large storage surfaces Drain system with containers for waste fluids Option: Integrated Vacutome Stretching sections and disposal of section debris via a suction device Suction power can be selected by the user Pre-cooled coarse filter of the dual filter system collects section debris and purifies the air Option: Specimen cooling with quick release mechanism Specimen cooling is completely integrated into the microtome Chamber volume and storage shelves are completely maintained Quick release mechanism for clamping chucks allows for fast changing of specimen Option: Motorized cutting drive Three different cutting modes Double click philosophy provides protection against unintended motion

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5 NEW Overcoming obstacles of Uncompromised safety with a vast variety of additional application options conventional disinfection No interruption of your workflow Current disinfection after warming up the cryo-chamber takes up to 3 hours with cold disinfection you are ready in just 3 minutes Complete disinfection of the entire cryo-chamber Not all current disinfections are fully effective, for example, with UV light only disinfects the areas reached by light cold disinfection reaches the entire cryo-chamber No health risks caused by the disinfectant reagent Current disinfection, for example, by vaporization of formalin or others, is potentially toxic cold disinfection with Sanosil is nontoxic with proven effectivness See the benefits of the new cold disinfection system at:

6 Thermo Scientific Microm HM550 cryostat with cold disinfection specifications Dimensions (W, D, H) Weight Certificates 640 (w/o handwheel) x 760 x 1200 (w/o stage) mm kg (depending on model) CE; c-csa-us Easy-to-read displays show important data such as set/actual temperature, section sum, remaining travel, number of sections, actual time, trim and fine sectioning thickness, retraction function Automatic approach system (ACA) for quick, precise and safe movement of the specimen towards the knife and/or blade Electronical handwheel brake can be locked in any position Continuous temperature control of the cooling chamber from 0 C to -35 C Fast freezing station for the simultaneous initial freezing of 12 specimens (30 mm chucks) Automatic defrosting function for immediate on-demand defrosting Heated sliding window Energy saving modes: standby and sleep-mode High performance rotary microtome Section thickness range from 1 μm 100 µm FINE section thickness range from 1 μm 10 µm in 1 µm steps from 10 μm 20 µm in 2 µm steps from 20 μm 100 µm in 5 µm steps TRIMMING section thickness range from 5 μm 500 µm from 10 μm 100 µm in 10 µm steps from 100 μm 200 µm in 20 µm steps from 200 μm 500 µm in 50 µm steps Max. specimen size 70 x 55 mm Total horizontal feed µm Vertical cutting stroke 60 mm Sample orientation 8 along the X-Y-axis, rotatable 360 Sample retraction during return stroke 40 µm, can be deactivated Intuitive 0-positioning of the object orientation Accelerated object holder return movement for fast operation Cutting speed mm/s, can be continuously adjusted (motor option) Cutting window selectable (motor option) Continuous specimen temperature control from +10 C to -50 C (object cooling option) Coarse feed and reset three different sped levels (motor option) Three operating modes interval, single and continuous stroke (motor option) Motorized sectioning controlled via foot pedal or button Motor brake and emergency stop switch for safe operation (motor option) Integrated Vacutome system for stretching cryo sections as well as debris removal (vacutome option) Integrated fast freezing device with separate cooling element (Peltier) down to max. -60 C for four specimen (30 mm chucks) (option) Power supply V 1.6 A +/-10% Hz 2010 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries. ROWMAMI/1001/0043GB Anatomical Pathology 4481 Campus Drive Kalamazoo, MI USA +1 (800) Robert-Bosch-Strasse Walldorf GERMANY + 49 (0)