ReadyKart mobile processing station

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GE Healthcare Data file 28-9606-48 AA ReadyToProcess ReadyKart mobile processing station ReadyKart Mobile Processing Stations (Fig 1) fit well with the goals of scientists, process engineers, and laboratory technicians who must configure fluid processing systems for product and process development or pilot manufacturing. When used with GE Healthcare s family of ReadyToProcess components, users can quickly configure a wide range of sterile and disposable fluid processing systems. Since the ReadyKart enables the ergonomic placement of equipment, users perform their tasks faster and better. ReadyKart mobile processing station delivers: Quick and convenient setup of fluid processing equipment saves time and allows users to do their best work Nesting capabilities with hose/tubing routing enables integration of multi-step processes Available components and optional equipment supports a wide range of fluid processing setups The ReadyKart Mobile Processing Station is a configurable cart that mechanically supports and enhances the use of GE Healthcare ReadyToProcess fluid processing products. Fig 1. Standard ReadyKart with CFF ReadyCircuit installed.

Optimize your process and your results Organizing and optimizing the placement of fluid processing components minimizes hold-up volumes and leads to better outcomes. ReadyKart Mobile Processing stations can support all the equipment that experienced scientists and engineers need to complete these processes: Aseptic clarification and purification of vaccines and monoclonals Aseptic cell processing Manufacturing of materials for preclinical through Phase II clinical trials Fast Trak drug development processes Versatile approach to fluid processing Similar to other ReadyToProcess equipment, the ReadyKart offers versatility that simplifies your work and makes you more efficient. ReadyKarts accommodate and organize the following fluid processing components: Configurable and stackable shelves support pumps, process sensor monitors, and trays and bins that hold processing bags Bag holders are height adjustable to accommodate any size pillow bags up to 20 l, including non-ge Healthcare bags. Replaceable shelves with cutouts accept bins that hold 100 l and 200 l, 3-D bags. Push handles on both ends of the full size cart provide control during transportation. MiniKart has a handle only at one end. Removable plastic end plate restricts, shields, or allows access to processing equipment. Endplate includes six cable-tubing routing ports. Two sizes to meet your needs GE Healthcare manufactures the ReadyKart Mobile Processing Station in two sizes: Standard and Mini. Each size includes two configurations: (1) the base framework with wheels to which you add individual components to meet your specific requirements; and (2) a fully configured cart that includes the framework and components most users need for fluid processing applications. Trays and bins tilting trays hold and tilt pillow bags horizontally. Bins hold large 3-D bags. Both allow convenient routing of inlet and outlet port tubing. Holders for bags and filters adjustable-height bag holders hold pillow bag vertically. Filter holders support normal- and cross-flow filters attached with laboratory clamps. Bags and filters are held at convenient heights for easy setup and monitoring. Nest carts to form a system You can nest ReadyKarts and thread tubing and cables through the ports in the blue plastic endplates to create inline, multistage processes to replicate real world processing. This capability also minimizes holdup volumes and prevents accidental disconnecting of cable and tubing during processing. Features to make your work easy ReadyKarts are manufactured out of 304 stainless steel to minimize maintenance and provide long service life. Two 360-degree, heavy-duty casters make the cart easy to move even when fully loaded. The cart fits through standard doors. Other user-friendly features include: Bag holders rotate in 90-degree increments to accommodate bag style and equipment configuration. Fig 2. Mini Kart with additional shelving and circuit components. 2

Fig 3. Two ReadyKart mobile processing stations: WAVE and ReadyCircuit components installed. Materials of construction Frame: 304 stainless steel with M4 material finish, strip polished to 150 grit finish and chemically passivated Bins, trays, and shelves: naturally translucent polypropylene Rubber wheels and plastic endplate Related literature Data Files Code Number ReadyCircuit bags and tubing assemblies 28-9606-44 ReadyKart mobile processing station 28-9606-48 Sterile ReadyToProcess Hollow Fiber Cartridges 28-9798-79 Sterile ReadyToProcess ULTA NFF Capsules 28-9257-93 ReadyMate Disposable Aseptic Connectors 28-9379-02 Instructions for use ReadyCircuit bags, tubing assemblies, and filters 28-9606-46 ReadyKart mobile processing station 28-9606-47 Sterile RTP Hollow Fiber Cartridges 28-9226-84 Sterile ReadyToProcess ULTA NFF Capsules 28-9608-22 ReadyMate Disposable Aseptic Connectors 28-9385-70 ReadyClamp 28-9406-20 Quick Reference Guides ReadyCircuit Components 28-9750-67 ReadyKart Mobile Processing Station 28-9750-72 ReadyToProcess CFF cartridge 28-9776-40 3

Specifications Mini mobile processing station Product characteristic Dimensions, assembled, (W H D) Dimensions, assembled, with stackable shelves: (W H D) Height to top of filter rod holder Height to top of bag holder when fully extended Clearance (height) needed to install filter holder rod Clearance (height) needed to install bag holder arm Distance between shelves Processing station bottom shelf and middle shelf Processing station middle shelf and top shelf Processing station top shelf and first shelf of stackable module Stackable module first shelf and stackable module second shelf Shipping weight of processing station frame Stackable shelf module weight Maximum net operating load, cart with stackable shelves Maximum net operating load, cart only Maximum net operating load, stackable shelf unit only Standard mobile processing station Product characteristic Dimensions, assembled (W H D) Dimensions, assembled, with shelves (W H D) Height to top of filter rod holder Height to top of bag holder when fully extended Clearance (height) needed to install filter holder rod Clearance (height) needed to install bag holder arm Distance between shelves: Processing station bottom shelf and middle shelf Processing station middle shelf and top shelf Processing station top shelf and first shelf of stackable module Stackable module first shelf and stackable module second shelf Shipping weight if processing station frame Stackable shelf module weight Maximum net operating load, cart with stackable shelves Maximum net operating load, cart only Maximum net operating load, stackable shelf unit only Specification 78.4 97.8 71.1 cm (31 38.5 28 in) 78.4 148.6 71.1 cm (31 58.5 28 in) 161.3 cm (63.5 in) 167.6 cm (66 in) 176.5 cm (69.5 in) 190.5 cm (75 in) 36.8 cm (14.4 in) 35.6 cm (14 in) 56.7 kg (125 lb) 13.6 kg (30 lb) 453 kg (1000 lb) 340 kg (750 lb) 113 kg (250 lb) Specification 116.8 97.8 71.1 cm (46 38.5 28 in) 116.8 148.6 71.1 cm (46 58.5 28 in) 161.3 cm (63.5 in) 167.6 cm (66 in) 176.5 cm (69.5 in) 190.5 cm (75 in) 36.8 cm (14.4 in) 35.6 cm (14 in) 79.4 kg (175 lb) 19.5 kg (43 lb) 453 kg (1000 lb) 340 kg (750 lb) 113 kg (250 lb) 4

Ordering information Article Catalog Description Usage guide number number ReadyKart full size accessories and replacement parts 28977894 28977894 ReadyKart with 3 shelves Basic full size cart pre-configured with a bottom stainless steel shelf and 2 solid shelves, 2 arm clamp assemblies to hang bags, 2 hanging bag protectors and 1 filter holder rod and clamp assembly and 1 end panel 28977896 28977896 ReadyKart frame for 3 shelves Basic full size cart frame with a stainless steel bottom shelf will accept up to 2 removable shelves to be accessorized as required 28977908 28977908 ReadyKart shelf no tank hole Replacement part Accessory for full cart frame, up to 2 required depending on desired configuration 28977909 28977909 ReadyKart t-shelf with tank hole Accessory, 2 required if using 200 L tank, 1 required if using 100 L tank 28977899 28977899 ReadyKart top shelf assembly Accessory for full size cart added 2-shelf capability (transport to freezing, storage, cascading process train). When installed, unable to use filter holder rods. ReadyKart mini accessories and replacement parts 28977897 28977897 ReadyKart mini with 3 shelves Basic half size cart pre-configured with a bottom stainless steel shelf and 2 solid shelves, 1 arm clamp assemblies to hang bags, 1 hanging bag protectors and 1 filter holder rod and clamp assembly 28977898 28977898 ReadyKart mini frame for 3 shelves Basic half size cart frame with a stainless steel bottom shelf will accept up to 2 removable shelves to be accessorized as required 28977910 28977910 ReadyKart mini shelf no tank hole Replacement par Accessory for minicart frame, up to 2 required depending on desiredconfiguration 28977913 28977913 ReadyKart mini shelf with tank hole Accessory, 2 required if using 200 L tank, 1 required if using 100 L tank 28977900 28977900 ReadyKart mini top shelf assembly Accessory for half size cart added 2-shelf capability (transport to freezing, storage, cascading process train). When installed, unable to use filter holder rods. 5

Ordering information Article Catalog Description Usage guide number number ReadyKart accessories that fit the full and mini sizes 28977903 28977903 ReadyKart 200 L tank Requires 2 shelves with tank holes. Catalog number 28977909 on full size cart or catalog number 28977913 on the mini cart 28977904 28977904 ReadyKart 100 L tank Requires 1 shelf with tank hole in the upper shelf of the cart. Catalog number 28977909 on full size cart or catalog number 28977913 on the mini cart 28977905 28977905 ReadyKart 1 and 5L tray Accessory support, recommended for pillow bags and hanging bags used as pillow bags 28977906 28977906 ReadyKart 10, and 20 L tray Accessory support, recommended for pillow bags and hanging bags used as pillow bags, can be mounted across width of carts 28977907 28977907 ReadyKart 50 L tray Accessory support, recommended for 50 L pillow bags. 28977902 28977902 ReadyKart filter holder rod Accessory required to hold filters vertical at cart corners, requires filter holder clamp or customer supplied equal. Cannot use if top shelf assembly in place. 28977926 28977926 ReadyKart filter holder clamp Accessory required to hold filters vertical at cart corners, requires filter holder rod (should this be part of an assembly with the rod and also as a replacement part 28977901 28977901 ReadyKart arm clamp assembly Accessory required to hold hanging boat fitment bags, recommend hanging bag plate for added bag protection 28977917 28977917 ReadyKart hanging bag plate Accessory recommended for protection of hanging bag that would rest against the arm clamp assembly ReadyKart replacement parts 28977922 28977922 ReadyKart tray lift assembly Replacement part 28977923 28977923 ReadyKart arm clamp Replacement part 28977924 28977924 ReadyKart arm glide insert Replacement part 28977918 28977918 ReadyKart arm gas spring Replacement part 28977925 28977925 ReadyKart arm glide locator Replacement part 28977920 28977920 ReadyKart swivel lock caster Replacement part 28977919 28977919 ReadyKart fixed caster Replacement part 28977921 28977921 ReadyKart end panel Replacement part For local office contact information visit: www.gelifesciences.com/contact GE Healthcare Bio-Sciences AB Björkgatan 30 751 84 Uppsala Sweden www.gelifesciences.com GE, imagination at work and GE monogram are trademarks of General Electric Company. ReadyKart, ReadyToProcess, and ULTA are trademarks of GE Healthcare companies. All third party trademarks are the property of their respective owners. 2010 General Electric Company - All rights reserved. All goods and services are sold subject to the terms and conditions of sale of the company within GE Healthcare which supplies them. A copy of these terms and conditions is available on request. Contact your local GE Healthcare representative for the most current information.contact your local GE Healthcare representative for the most current information. GE Healthcare Bio-Sciences AB, Björkgatan 30, 751 84 Uppsala, Sweden GE Healthcare Bio-Sciences Corp., 800 Centennial Avenue, P.O. Box 1327, Piscataway, NJ 08855-1327 USA GE Healthcare Europe, GmbH, Munzinger Strasse 5, D-79111 Freiburg, Germany GE Healthcare Japan Corporation, Sanken Bldg., 3-25-1, Hyakunincho, Shinjuku-ku, Tokyo 169-0073 Japan 28-9606-48 AA 06/2010 GEHC0063 6