LEADERS IN STERILIZATION SINCE 1884

LEADERS IN STERILIZATION SINCE 1884 AUTOCLAVE AND EDS PRODUCT GUIDE

Why choose Astell? Leaders in sterilization since 1884 CUSTOM SOLUTIONS Custom and standard solutions to meet your specification Here at Astell we take pride in producing a comprehensive range of autoclaves and sterilizers, all of which can be found on the following pages. Together with a selection of options, we are confident we can supply the right equipment for your needs. However, there are often many considerations and sometimes an off the peg solution isn t suitable. As and where necessary, Astell can take the best elements and features to create a custom sterilization unit that fits your installation space, budget or process needs. GLOBAL REACH Our products are used in over 100 countries, worldwide Having been in business for over a century, Astell can lay claim to a long list of satisfied customers. A large percentage of these are overseas customers who have either purchased from us directly or through an approved agent. A list of dealer partners can be found on our website. Can t see a dealer covering your location? Please contact us to discuss your requirements. SERVICE AND MAINTENANCE Quality maintenance and rapid after-sales support We offer service support using experienced specialist engineers, OEM parts and with fast response times. Should you experience a technical problem, contact our dedicated team and it will be our priority to help rectify it. However be reassured, it s not uncommon for us to be contacted by customers that have Astell autoclaves more than 15 years old which are still working perfectly! MADE IN THE UK SINCE 1884 Over 130 years experience goes into every unit we manufacture Uniquely, Astell can trace its heritage back over 130 years to the early pioneering days of steam sterilization. Throughout this time our autoclaves have been manufactured in the UK using high quality components, to exceed current industry standards. Choose Astell Scientific and become part of our story! Standards Compliance: In accordance with the requirements of Astell Scientific s notified bodies and continuous improvement Quality Management System we maintain accreditation to the following standards and directives: ISO 9001:2008 ISO 13485:2012 ISO 17025:2005 IEC 61010 ASME U VIII EN285:2015 EMC EN 61326-1: 2013 BS13060:2014 Medical Devices Directive (93/42/EC) Pressure Equipment Directive (PED 2014/68/EU) 2 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

Contents 2 Benchtop Autoclave Range 33, 43, 63 litre models 4 Compact Autoclave Range 63 litre model 6 Top Loading Autoclave Range 95, 120, 135 litre models 8 Front Loading Autoclave Range 120, 153, 247, 290, 344 litre models 10 Duaclave Autoclave Range 66, 86, 126, 240, 306 litre models 12 SQUARE ECO Autoclave Range 125, 216, 250, 360 litre models 14 SQUARE Autoclave Range 125-735 litre models 16 SQUARE MAX Autoclave Range 600 1400 litre models 17 Double Door SQUARE Autoclave Range 250 1200 litre models 19 Touchscreen controller 20 Options and Accessories 22 Steam Generators explained 23 Cooling options explained 24 Air Ballast and Load Sensed Timing explained 25 Simple and Advanced Vacuum explained 26 Service and Maintenance 27 Steam Generator Range 24kW, 48kW and 72kW models 28 Effluent Decontamination Systems Batch sterilization for BSL3 waste 29 Nelldorn Glassware Dryer Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 1

Benchtop Autoclave Range 33, 43, 63 litre models Fitted with heaters in chamber as standard Astell s front loading Benchtop autoclave range is available in three sizes and is totally self-contained. These units require no plumbing, and only a standard single phase power supply. The range is available as either Classic or Autofill. Classic The Classic version requires manual water-fill and during the cycle condensate leaves the vessel via a silicone tube that can be connected to a heat-resistant bottle. Autofill The Autofill version has an integral reservoir and an in-built water re-circulation system. Once the reservoir is filled, this provides water for up to 15 cycles, and also acts as a collection vessel for condensate and the water that is automatically returned from the chamber at the end of each cycle, minimising water usage. Other features include: Media holdwarm and delayed start facility A 5.7 colour touchscreen with integrated USB data port Electropolished stainless steel chamber Simple pre-post vacuum option available Adjustable time and temperature Low water and power consumption Specifications Model no. Classic/ Autofill Steam source Volume (litres) 33 Power supply Chamber diam. x depth (mm) Usable chamber depth (mm) Overall dimensions AMB420 346 x 355 294 520 x 600 x 805 670 AMB430 Classic 43 Single 346 x 465 403 520 x 600 x 805 670 AMB440 Phase, Heaters in 63 346 x 668 600 520 x 600 x 1005 855 230V, 13A, AMB220 Chamber 33 50/60 Hz 346 x 355 294 520 x 600 x 805 670 AMB230 Autofill 43 346 x 465 403 520 x 600 x 805 670 AMB240 63 346 x 668 600 520 x 600 x 1005 855 (Power consumption/dimensions may vary with the addition of certain options) Required bench depth (mm) Bottle capacity Below is a table identifying the number of Duran bottles it is possible to fit in to the chamber of each model using the standard base shelf. Model no. 500ml 1000ml 2000ml AMB420/AMB220 10 8 2 AMB430/AMB230 14 11 3 AMB440/AMB240 21 15 4 2 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Advanced options (Selection of this option alters the power supply requirements listed in the Specifications table) Vac Simple Vacuum Option The AVC002 vacuum utilises the standard heaters in the base of the chamber with simple pre-vacuum air removal and post vacuum cooling to effectively sterilize porous type loads and difficult discard loads, but without any drying capability. Astell Ref: AVC002. Additional options Load Sensed Process Timing Ref: AAR014 Category III (BSL-3) compliance Ref: AVQ006 Pulsar Freesteaming Integral data printer Remote maintenance/diagnosis Ethernet interface IQ/OQ documentation Ref: AAN009 Ref: AAR130 Ref: RDM101 Ref: AAR122 Ref: IQ/OQ Five position shelf rack (AMB420/AMB220) Two shelves supplied Five position shelf rack (AMB430/AMB230) Three shelves supplied Five position shelf rack (AMB440/AMB240) Three shelves supplied Ref: AAN025 Ref: AAN530 Ref: AAN040 Assisted air cooling Ref: AAP007 Spare shelf (AMB420/AMB220) Ref: AAN022 Condensate bottle (Classic models only) Ref: AAN308 Spare shelf (AMB430/AMB230) Ref: AAN532 Morrison discard container (W:180 x H:200 x D:260mm) Ref: AAN346 Spare shelf (AMB440/AMB240) Ref: AAN043 See pages 20-25 for further information explaining options and accessories Options capacity Part name Part ref. Dimensions AMB420 & AMB220 AMB430 & AMB230 Morrison discard container AAN346 180 x 200 x 260 1 2 3 5 position shelf kit Various Fitted to chamber 2* 3* 3* (*indicates the number of moveable shelves provided with the 5 position shelf kit. Additional shelves available separately) AMB440 & AMB240 Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table. Benchtop units require a standard single phase power supply. N.B. A Neutral line and protective Earth are required for all electrically heated units. Drainage requirements (Classic models only): A condensate bottle (Ref: AAN308) or a similar heat resistant receptacle. Touchscreen controller Autofill reservoir Pressure gauge Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 3

Compact Autoclave Range 63 litre model Fitted with heaters in chamber as standard Astell s top loading Compact autoclave range is available in two versions and each is totally self-contained. These units require no plumbing, and only a standard single phase power supply. The range is available as either Classic or Autofill. Classic The Classic version requires manual water-fill and during the cycle condensate leaves the vessel via a silicone tube that can be connected to a heat-resistant bottle. Autofill The Autofill version has an integral reservoir and an in-built water re-circulation system. Once the reservoir is filled, this provides water for up to 15 cycles, and also acts as a collection vessel for condensate and the water that is automatically returned from the chamber at the end of each cycle, minimising water usage. Other features include: A 5.7 colour touchscreen with integrated USB data port Electropolished stainless steel chamber Low water and power consumption Castor mounted for easy movement Media holdwarm and delayed start facility Specifications Model no. Classic/ Autofill Steam source Volume (litres) Power supply 63 Single Phase, 230V, 13A, 50/60 Hz Chamber diam. x depth (mm) Usable chamber depth (mm) Overall dimensions AMA440 Classic Heaters in 346 x 668 576 530 x 1070 x 705 AMA240 Autofill Chamber 63 346 x 668 576 530 x 1070 x 705 Bottle capacity Below is a table identifying the number of Duran bottles it is possible to fit in to the chamber of each model using the standard base shelf. Model no. 500ml 1000ml 2000ml AMA440 16 10 6* AMA240 16 10 6* *8 x 2000ml Durans can be accommodated without the use of baskets, but this requires an additional Load Support Plate. Astell Ref: AAN074. 4 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Additional options Load Sensed Process Timing Ref: AAR014 Condensate bottle (Classic model only) Ref: AAN308 Pulsar Freesteaming Integral data printer Remote maintenance/diagnosis Ref: AAN009 Ref: AAR130 Ref: RDM101 Category III (BSL-3) compliance Stainless steel basket (D:310 x H:270 mm) Ref: AVQ006 Ref: AAN340 Ethernet interface IQ/OQ documentation Ref: AAR122 Ref: IQ/OQ Morrison discard container (D:310 x H:270 mm) Ref: AAN342 Assisted air cooling Ref: AAP007 Load support plate Ref: AAN074 See pages 20-25 for further information explaining options and accessories Condensate bottle The condensate bottle can be connected to any of the Classic model autoclaves to allow up to 4 litres of water collection during and after the sterilization cycle. This option is useful in situations where no easy drainage is available, or as a lower cost alternative to the Autofill versions. Astell Ref: AAN308. Options capacity Part name Part ref. Dimensions: Diameter x Height (mm) AMA440 & AMA240 Morrison discard container AAN342 310 x 270 2 Stainless steel basket AAN340 310 x 270 2 Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table. Compact units require a standard single phase power supply. N.B. A Neutral line and protective Earth are required for all electrically heated units. Drainage requirements (Classic models only): A condensate bottle (Ref: AAN308) or a similar heat resistant receptacle. Touchscreen controller Data printer (optional) Pressure gauge Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 5

Top Loading Autoclave Range 95, 120, 135 litre models Fitted with heaters in chamber as standard Astell s top loading autoclave range is available in three sizes and is factory fitted with a large number of features as standard, making it suitable for sterilizing liquids (media), discard, glassware and other instruments. These features include: A 5.7 colour touchscreen with integrated USB data port A delayed start and a media holdwarm feature for greater control over when you want to sterilize Safety: over-temperature protection, an external pressure gauge, a cooling lock, a safety valve test program and an emergency stop button A validation port, drain valve and an electropolished stainless steel chamber Castor mounted for easy movement Timed/Pulsed Freesteaming Full range of options and accessories (see opposite page for details) Low water and power consumption Specifications Model no. Steam source Volume (litres) Power supply Chamber diam. x depth (mm) Usable chamber depth (mm) Overall dimensions AMA250 95 456 x 584 449 660 x 940 x 840 AMA260 Heaters in Chamber 120 Single or 3 Phase, 7/10kW 456 x 736 601 660 x 1070 x 840 AMA270 135 456 x 817 682 660 x 1150 x 840 AMA260 Integral Steam Generator 120 456 x 736 601 660 x 1070 x 1200 3 Phase, 14kW AMA270 (option) 135 456 x 817 682 660 x 1150 x 1200 (Power consumption/dimensions may vary with the addition of certain options) Bottle capacity Below is a table identifying the number of Duran bottles it is possible to fit in to the chamber of each model. The number in brackets indicates the quantity of stainless steel baskets (Ref: AAN042) required to achieve this. Model no. 500ml 1000ml 2000ml AMA250 30 (2) 10 (1) 5 (1) AMA260 30 (2) 20 (2)* 10 (2)* AMA270 45 (3) 20 (2)* 10 (2)* * (As the Duran bottle height exceeds the basket height, in this configuration the second basket would rest on top of the bottles in the lower basket). 6 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Advanced options (Selection of these options alters the power supply requirements listed in the Specifications table) Sg Vac Jac Integral Steam Generator Option The standard heaters in chamber are replaced with a 12kW integral steam generator. This option helps to improve cycle times by increasing the efficiency of steam production (a mains water supply is required for this option). Astell Ref: 12KWSG. Advanced and Simple Vacuum Options A vacuum option is essential for porous type loads (e.g. wrapped instruments and fabrics) or other cycles where air pockets could easily become trapped within the load. Available in 2 derivatives, the AVC001 option is Astell s advanced pulsar vacuum, which when used in conjunction with the integral steam generator and a heated jacket enables the dry output of all loads. Alternatively, the AVC002 vacuum utilises the standard heaters in the base of the chamber with simple pre-vacuum air removal and post vacuum cooling to effectively sterilize porous type loads and difficult discard loads, but without any drying capability. Astell Ref: AVC001 or AVC002. External Jacket Option Requiring the steam generator or direct steam option (and normally in conjunction with the AVC001 vacuum option), the external jacket option effectively adds an additional layer to the outside of the autoclave chamber. This can then be independently heated by the steam generator to enhance the drying process at the end of the cycle, or it can be flooded with water during cooling to aid faster cooling times. Astell Ref: AJP150. Additional options Load Sensed Process Timing Ref: AAR014 Air ballast (requires compressed air) Ref: AVC004E Pulsar Freesteaming Ref: AAN009 Drain Cooling (heaters in chamber model only) Ref: AAN420 Integral data printer Ref: AAR130 Category III (BSL-3) compliance Ref: AVQ006 Remote maintenance/diagnosis Ref: RDM101 Stainless steel basket (D:400 x H:220mm) Ref: AAN042 Ethernet interface Ref: AAR122 Stainless steel basket (D:400 x H:400mm) Ref: AAN036 IQ/OQ documentation Ref: IQ/OQ Morrison discard container (D:390 x H:355mm) Ref: AAN058 Assisted air cooling Ref: AAP006 Morrison discard container (D:390 x H:500mm) Ref: AAN056 Advanced water cooling Ref: AAP080 Water softener (compact) Ref: AAW002 Autodrain (heaters in chamber models only) Ref: AAP018 Load support plate Ref: AAN002 Autofill (heaters in chamber models only) Ref: AAP019 Direct Steam model Ref: Various See pages 20-25 for further information explaining options and accessories Options capacity Part name Part ref. Dimensions: Diameter x Height (mm) AMA250 AMA260 AMA270 Stainless steel basket AAN042 400 x 220 2 2 3 Stainless steel basket AAN036 400 x 400 1 1 1 Morrison discard container AAN056 390 x 500 1 1 1 Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table, however these can vary depending on the options selected. Options that affect the power requirement are Integral Steam Generator and Advanced and Simple Vacuum. For details on the exact power requirements on these options please contact us. N.B. A Neutral line and protective Earth are required for all electrically heated units. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required for the Autofill, vacuum and water cooling options. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (35mm diameter) capable of withstanding temperatures up to 100 C. Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 7

Front Loading Autoclave Range 120, 153, 247, 290, 344 litre models Fitted with heaters in chamber as standard Astell s front loading Swiftlock autoclave range is available in five sizes and is factory fitted with a large number of features as standard, making it suitable for sterilizing liquids (media), discard, glassware and other instruments. These features include: A 5.7 colour touchscreen with integrated USB data port A delayed start and a media holdwarm feature for greater control over when you want to sterilize Safety: over-temperature protection, an external pressure gauge, a cooling lock, a safety valve test program and an emergency stop button A validation port, drain valve and an electropolished stainless steel chamber Safe and easy loading, plus Astell s unique Swiftlock door closure system Timed/Pulsed Freesteaming Full range of options and accessories (see opposite page for details) Low water and power consumption Specifications Model no. Steam source Volume (litres) Power supply 120 Single or 3 Phase, 7/10kW Chamber diam. x depth (mm) Usable chamber depth (mm) Overall dimensions ASB260 454 x 740 633 685 x 1320 x 1100 ASB270 153 454 x 945 862 685 x 1320 x 1310 ASB280 Heaters in Chamber 247 3 Phase, 13kW 600 x 876 734 900 x 1405 x 1370 ASB290 290 600 x 1024 886 900 x 1405 x 1370 3 Phase, 16kW ASB300 344 600 x 1217 1086 900 x 1405 x 1570 ASB260 120 454 x 740 633 685 x 1320 x 1500 Integral 3 Phase, 18kW ASB270 153 454 x 945 862 685 x 1320 x 1500 Steam Generator ASB280 247 600 x 876 734 900 x 1405 x 1750 ASB290 (option) 290 3 Phase, 28kW 600 x 1024 886 900 x 1405 x 1750 ASB300 344 600 x 1217 1086 900 x 1405 x 1750 (Power consumption/dimensions may vary with the addition of certain options) Bottle capacity Below is a table identifying the number of Duran bottles it is possible to fit in to the chamber of each model using the standard base shelf. The number in brackets indicates quantity of extra bottles with the addition of a centre shelf (optional extra). Model no. 500ml 1000ml 2000ml ASB260 24 18 8 ASB270 33 23 11 ASB280 41 (+9) 28 (+4) 15 ASB290 50 (+11) 32 (+4) 18 ASB300 63 (+14) 42 (+6) 23 8 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Advanced options (Selection of these options alters the power supply requirements listed in the Specifications table) Sg Vac Jac Integral Steam Generator Option The standard heaters in chamber are replaced with a 16kW/24kW integral steam generator. This option helps to improve cycle times by increasing the efficiency of steam production and also includes automatic water filling as standard, removing the requirement of manually filling the machine with water between sterilization cycles (a mains water supply is therefore required for this option). Astell Ref: 16KWSG or 24KWSG. Advanced and Simple Vacuum Options A vacuum option is essential for porous type loads (e.g. wrapped instruments and fabrics) or other cycles where air pockets could easily become trapped within the load. Available in 2 derivatives, the AVC001 option is Astell s advanced pulsar vacuum, which when used in conjunction with the integral steam generator and a heated jacket enables the dry output of all loads. Alternatively, the AVC002 vacuum utilises the standard heaters in the base of the chamber with simple pre-vacuum air removal and post vacuum cooling to effectively sterilize porous type loads and difficult discard loads, but without any drying capability. Astell Ref: AVC001 or AVC002. External Jacket Option Requiring a steam generator or direct steam option (and normally in conjunction with the AVC001 vacuum option), the external jacket option effectively adds an additional layer to the outside of the autoclave chamber. This can then be independently heated by the steam generator to enhance the drying process at the end of the cycle, or it can be flooded with water during cooling to aid faster cooling times. Astell Ref: AJP100 or AJP152. Additional options Load Sensed Process Timing Ref: AAR014 Internal convection cooling Ref: AAP102 Pulsar Freesteaming Integral data printer Remote maintenance/diagnosis Ethernet interface IQ/OQ documentation Assisted air cooling/non jacketed Advanced water cooling Autodrain (heaters in chamber models only) Autofill (heaters in chamber models only) Air ballast (requires compressed air) Ref: AAN009 Ref: AAR130 Ref: RDM101 Ref: AAR122 Ref: IQ/OQ Ref: AAP006 Ref: AAP100 Ref: AAP018 Ref: AAP019 Ref: AVC004 Drain Cooling (heaters in chamber model only) Category III (BSL-3) compliance Morrison discard container (W:280 x H:290 x D:330mm) Container tray (W:279 x H:127 x D:279mm) Additional shelf kit (for ASB260/ASB270) Additional shelf kit (for ASB280/ASB290/ASB300) Water softener (compact) Integral air compressor (req. for Vacuum units) Blow down vessel (steam gen. only) Direct Steam model Castors option Ref: AAN420 Ref: AVQ006 Ref: AAN300 Ref: AAN080 Ref: AAN316 Ref: AAN318 Ref: AAW002 Ref: AAQ503 Ref: SPL285 Ref: Various Ref: AAC006 See pages 20-25 for further information explaining options and accessories Options capacity Part name Part ref. Dimensions ASB260 ASB270 ASB280 ASB290 ASB300 Morrison discard container AAN300 280 x 290 x 330 1 3 2 3 3 Container tray AAN080 279 x 127 x 279 2 3 2 3 3 Container tray (capacity with middle shelf optional extra) 4 6 6 9 9 Container tray (capacity with middle & upper shelf extras) 6 12 12 Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table, however these can vary depending on the options selected. Options that affect the power requirement are Integral Steam Generator and Advanced and Simple Vacuum. For details on the exact power requirements on these options please contact us. N.B. A Neutral line and protective Earth are required for all electrically heated units. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required for the Autofill, vacuum and water cooling options. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (35mm diameter) capable of withstanding temperatures up to 100 C. Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 9

Duaclave Autoclave Range 66, 86, 126, 240, 306 litre models Fitted with heaters in chamber as standard The Duaclave is the ideal autoclave where laboratory space is at a premium. The Duaclave features two identical chambers, stacked one directly above the other, giving double the capacity for the same footprint. Combining two units within one frame, the two chambers operate completely independently for example, allowing you to run a glassware cycle in one chamber whilst preparing your media with the other. Duaclave models are only available with heaters in chamber. Features include: Media holdwarm and delayed start facility 5.7 colour touchscreens Electropolished stainless steel chambers External pressure gauges Versatile range of options and accessories (see opposite page for details) Over pressure/temperature protection Validation port Specifications Model no. From range Steam source Volume (litres) 33 (x2) Power supply Chamber diam. x depth (mm) Usable chamber depth (mm) Overall dimensions AMB420DV 2 x Single 346 x 355 (x2) 294 520 x 1200 x 780 AMB430DV Benchtop 43 (x2) Phase, 346 x 465 (x2) 403 520 x 1200 x 780 AMB440DV Heaters in 230V, 13A 63 (x2) Chamber 346 x 668 (x2) 600 520 x 1200 x 980 ASB260DV 120 (x2) 2 x Single/3Ph, 454 x 740 (x2) 633 685 x 1855 x 1310 Swiftlock ASB270DV 153 (x2) 7/10kW 454 x 945 (x2) 862 685 x 1855 x 1310 (Power consumption/dimensions may vary with the addition of certain options) Bottle capacity Below is a table identifying the total number of Duran bottles it is possible to fit in to each Duaclave chamber using the standard base shelf. Model no. 500ml 1000ml 2000ml AMB420DV 10 8 2 AMB430DV 14 11 3 AMB440DV 21 15 4 ASB260DV 24 18 8 ASB270DV 33 23 11 10 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Additional options AMB420DV AMB430DV AMB440DV Load Sensed Process Timing Ref: AAR014 Category III (BSL-3) compliance Ref: AVQ006 Pulsar Freesteaming Integral data printer Remote maintenance/diagnosis Ethernet interface Ref: AAN009 Ref: AAR130 Ref: RDM101 Ref: AAR122 Five position shelf rack (AMB420) Two shelves supplied Five position shelf rack (AMB430) Three shelves supplied Five position shelf rack (AMB440) Three shelves supplied Ref: AAN025 Ref: AAN530 Ref: AAN040 IQ/OQ documentation Ref: IQ/OQ Spare shelf (AMB420) Ref: AAN022 Assisted air cooling Ref: AAP006 Spare shelf (AMB430) Ref: AAN532 Morrison discard container (W:180 x H:200 x D:260mm) Ref: AAN346 Spare shelf (AMB440) Ref: AAN043 Additional options ASB260DV ASB270DV Load Sensed Process Timing Ref: AAR014 Internal convection cooling Ref: AAP102 Pulsar Freesteaming Ref: AAN009 Drain Cooling Ref: AAN420 Integral data printer Ref: AAR130 Category III (BSL-3) compliance Ref: AVQ006 Remote maintenance/diagnosis Ethernet interface Ref: RDM101 Ref: AAR122 Morrison discard container (W:280 x H:290 x D:330mm) Container tray (W:279 x H:127 x D:279mm) Ref: AAN300 Ref: AAN080 IQ/OQ documentation Ref: IQ/OQ Additional shelf kit (for ASB260/ASB270) Ref: AAN316 Assisted air cooling Ref: AAP006 Water softener (compact) Ref: AAW002 Advanced water cooling Ref: AAP100 Direct Steam model Ref: Various Autodrain Ref: AAP018 Castors option Ref: AAC006 Autofill Ref: AAP019 See pages 20-25 for further information explaining options and accessories Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table, however these can vary depending on the options selected. For details on the exact power requirements on these options please contact us. N.B. A Neutral line and protective Earth are required for all electrically heated units. AMB model drainage requirements: A condensate bottle or a similar heat resistant receptacle per chamber. Alternatively connection to a free venting, non-manifolded drain (35mm diameter) capable of withstanding temperatures up to 100 C. ASB model water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required for the Autofill option. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (35mm diameter) capable of withstanding temperatures up to 100 C. Low water and power consumption Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 11

SQUARE ECO Autoclave Range 125, 216, 250, 360 litre models Fitted with heaters in chamber as standard The SQUARE ECO range has been designed to bridge the gap between circular chamber autoclaves and the more complex square chamber autoclaves that Astell offer. The SQUARE ECO range still contains all the features you would expect from an Astell autoclave, including colour touchscreen, multiple programs for sterilizing and our delayed start/media holdwarm features, but this cost effective range has been designed with simplicity and economy in mind. The ECO range is manufactured using high quality materials and includes all the safety features you would expect to find on any of our smaller units, with a manual door. SQUARE ECO models are supplied with heaters in chamber. Features include: Media holdwarm and delayed start facility 5.7 colour touchscreen controller External pressure gauge Range of options and accessories (see opposite page for details) Assisted air cooling Autofill/Autodrain Over pressure/temperature protection Validation port Specifications Model no. Steam source Volume (litres) 125 Power supply Chamber dimensions Overall dimensions MNS125E 500 x 500 x 500 780 x 1750 x 1000 MNS216E Heaters in 415V, 3 Phase, 216 Chamber Neutral & Earth, 16kW 600 x 600 x 600 880 x 1850 x 1100 MNS250E 250 500 x 500 x 1000 880 x 1850 x 1750 Only suitable for fluid loads Model no. Steam source Volume (litres) Power supply Chamber dimensions Overall dimensions MNS360E Heaters in Chamber 360 415V, 3 Phase, Neutral & Earth, 16kW 600 x 600 x 1000 880 x 1850 x 1700 (Power consumption/dimensions may vary with the addition of certain options) Bottle capacity Below is a table identifying the total number of Duran bottles it is possible to fit in to each SQUARE ECO autoclave using the standard base shelf. The number in brackets indicates quantity of extra bottles with the addition of a centre shelf (optional extra). Model no. 500ml 1000ml 2000ml MNS125E 25 (30) 20 9 MNS216E 42 (42) 30 16 MNS250E 60 (60) 40 21 MNS360E 66 (66) 50 (50) 21 12 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Advanced options (Selection of this option alters the power supply requirements listed in the Specifications table) Vac Simple Vacuum Option The AVC002 vacuum utilises the standard heaters in the base of the chamber with simple pre-vacuum air removal and post vacuum cooling to effectively sterilize porous type loads and difficult discard loads, but without any drying capability. Astell Ref: AVC002. Additional options Load Sensed Process Timing Ref: AAR014 Category III (BSL-3) compliance Ref: AVQ006 Pulsar Freesteaming Ref: AAN009 Drain Cooling Ref: AAN420 Integral data printer Remote maintenance/diagnosis Ethernet interface Ref: AAR130 Ref: RDM101 Ref: AAR122 Discard container (W:300 x H:300 x D:300mm) Loading system 1 x external trolley + 1 x internal truck Ref: AAQ300 Ref: AAQ600 IQ/OQ documentation Ref: IQ/OQ Water softener Ref: AAW002 Castors option Ref: AAC006 Stainless steel fascia panelwork Ref: SSFPW See pages 20-25 for further information explaining options and accessories Standard safety features All SQUARE ECO range autoclaves are fitted with the following built-in safety features as standard: Over temperature protection, a cooling lock, a safety valve test program and emergency stop button The door mechanism is safety linked meaning a cycle cannot start until the door is properly closed; or opened until the pressure and temperature within the chamber is at a safe level The door seal is steam and vacuum resistant, and will seal effectively without trapping or entrapment of foreign material Doors are thermally insulated to prevent the surface temperature presenting a potential hazard to operators Installation requirements Power requirements: The power requirements for the standard machines are listed in the Specifications table, however these can vary depending on the options selected. For details on the exact power requirements on these options please contact us. N.B. A Neutral line and protective Earth are required for all electrically heated units. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (54mm diameter) capable of withstanding temperatures up to 100 C. Low water and power consumption Touchscreen controller Manual door Pressure gauge Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 13

SQUARE Autoclave Range 125 735 litre models Fitted with steam generator as standard Astell s SQUARE range offers the choice of seven different chamber sizes ranging from 125 to 735 litres and various heating, loading and door options. The SQUARE range is suitable for sterilizing glassware, fluids, waste and porous type loads (subject to configuration). Features include: 5.7 colour touchscreen controller 7 standard chamber sizes available Choice of three heating methods: Direct steam, heaters in chamber or with steam generator (subject to chamber size and load type) Single or double doors (pass through) Automatic or manual door operation Full range of options and accessories (see opposite page for details) Custom built units available to meet your exact requirements Specifications Models listed below are a representative selection. Please contact us for the full range of available sizes and options. Model no. Volume (litres) Doors Door mech. Steam generator Chamber dimensions Overall dimensions AVS125 125 1 Auto or Manual 24kW 500 x 500 x 500 780 x 2000 x 1300 AVS216 216 1 Auto or Manual 24kW 600 x 600 x 600 880 x 2000 x 1400 AVS250 250 1 or 2 Auto or Manual 24kW 500 x 500 x 1000 880 x 2000 x 1750 AVS360 360 1 or 2 Auto or Manual 24kW 600 x 600 x 1000 880 x 2000 x 1750 AVS490 490 1 or 2 Auto 48kW 700 x 700 x 1000 1250/1500 x 2000 x 1700 AVS612 612 1 or 2 Auto 48kW 700 x 700 x 1250 1250/1500 x 2000 x 2000 AVS735 735 1 or 2 Auto 48kW/72kW 700 x 700 x 1500 1250/1500 x 2000 x 2300 (Overall dimensions are based on single door models. May vary with the configuration and addition of certain options) Standard safety features All SQUARE range autoclaves are fitted with the following built-in safety features as standard: Over temperature protection, a cooling lock, a safety valve test program and emergency stop button The door mechanism is safety linked meaning a cycle cannot start until the door is properly closed; or opened until the pressure and temperature within the chamber is at a safe level The door seal is steam and vacuum resistant, and will seal effectively without trapping or entrapment of foreign material Doors are thermally insulated to prevent the surface temperature presenting a potential hazard to operators AVS735 fitted with optional stainless steel panels 14 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Advanced options (Selection of these options alters the power supply requirements listed in the Specifications table) Sg Vac Jac Integral Steam Generator Option The heaters in chamber are replaced with a 24kW/48kW integral steam generator. This option helps to improve cycle times by increasing the efficiency of steam production and also includes automatic water filling as standard, removing the requirement of manually filling the machine with water between sterilization cycles (a mains water supply is therefore required for this option). Astell Ref: 24KWSG or 48KWSG. Advanced Vacuum Option A vacuum option is essential for porous type loads (e.g. wrapped instruments and fabrics) or other cycles where air pockets could easily become trapped within the load. The AVC001 option is Astell s advanced pulsar vacuum, which when used in conjunction with the integral steam generator and a heated jacket enables the dry output of all loads. Astell Ref: AVC001. External Jacket Option Requiring a steam generator or direct steam option (and normally in conjunction with the AVC001 vacuum option), the external jacket option effectively adds an additional layer to the outside of the autoclave chamber. This can then be independently heated by the steam generator to enhance the drying process at the end of the cycle, or it can be flooded with water during cooling to aid faster cooling times. Astell Ref: AJP100 or AJP152. Additional options Integral data printer Ref: AAR130 Category III (BSL-3) compliance Ref: AVQ006 Load Sensed Process Timing Remote maintenance/diagnosis Ethernet interface IQ/OQ documentation Internal convection cooling Deluge cooling Air ballast (requires compressed air) Integral air compressor (Req. for Vacuum units) SPF seal (for double door machines only) Ref: AAR014 Ref: RDM101 Ref: AAR122 Ref: IQ/OQ Ref: AAP102 Ref: ADA100 Ref: AVC004 Ref: AAQ503 Ref: AVQ007 Morrison discard container (W:300 x H:300 x D:300mm) Additional shelf Water softeners Blow down vessel Loading systems Stainless steel pipework (primary) Stainless steel pipework (full) Castors option Ref: AAQ300 Ref: AAQ801 Ref: AAW002 Ref: SPL285 Ref: AAQ600/2 Ref: SPL430 Ref: SPL422 Ref: AAC006 Drain Cooling (heaters in chamber models only) Ref: AAN420 See pages 20-25 for further information explaining options and accessories Installation requirements Power requirements: The power requirements for the standard machines listed in the Specifications table are 415V, 3 Phase, with Neutral and Earth. Requirements can vary depending on the configuration and options selected. For additional details of exact power requirements please contact us. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (54mm diameter) capable of withstanding temperatures up to 100 C. Low water and power consumption Touchscreen controller Stainless steel pipework (optional) Pressure gauge Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 15

SQUARE MAX Autoclave Range 600 1400 litre models Fitted with steam generator/direct steam Astell s SQUARE MAX range offers the choice of five different chamber sizes ranging from 600 to 1400 litres and various heating, loading and door options. The SQUARE MAX range is highly customisable and by choosing from the many options available it is possible to sterilize almost anything (subject to configuration). Features include: 5.7 colour touchscreen controller 5 standard chamber sizes available Choice of two heating methods: Direct steam or steam generator Single or double doors (pass through) Automatic sideways opening door operation Full range of options and accessories (see page 18 for details) Custom built units available to meet your exact requirements Specifications Models listed below are a representative selection. Please contact us for the full range of available sizes and options. Model no. Volume (litres) Doors Steam generator Direct steam Chamber dimensions Overall dimensions SVS600 600 1 or 2 48kW 4kW 600 x 1000 x 1000 2000 x 2000 x 1500 SVS875 875 1 or 2 72kW 4kW 700 x 1000 x 1250 2000 x 2000 x 1750 SVS1050 1050 1 or 2 72kW 4kW 700 x 1000 x 1500 2000 x 2000 x 2000 SVS1200 1200 1 or 2 72kW 4kW 600 x 1000 x 2000 2000 x 2000 x 2500 SVS1400 1400 1 or 2 72kW 4kW 700 x 1000 x 2000 2000 x 2000 x 2500 (Overall dimensions are based on single door models. May vary with the configuration and addition of certain options) Standard safety features All SQUARE MAX range autoclaves are fitted with the following built-in safety features as standard: Over temperature protection, a cooling lock, a safety valve test program and emergency stop button The door mechanism is safety linked meaning a cycle cannot start until the door is properly closed; or opened until the pressure and temperature within the chamber is at a safe level The door seal is steam and vacuum resistant, and will seal effectively without trapping or entrapment of foreign material Doors are thermally insulated to prevent the surface temperature presenting a potential hazard to operators Water conservation re-circulation system minimising water usage SQUARE MAX fitted with optional stainless steel panels 16 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Double Door SQUARE Autoclave Range 250 1200 litre models Fitted with steam generator as standard Astell s Double Door range of SQUARE autoclaves are ideal for high-containment type facilities that may be handling dangerous pathogens and microorganisms, and/or where a specific area or clean room are isolated. The Double Door range offers the capability to specify a pass-through machine in various sizes with options for heating, loading and door specifications. The Double Door range is highly customisable and by choosing from the many options available it is possible to sterilize almost anything (subject to configuration). Features include: 5.7 colour touchscreen controller 5 standard chamber sizes available Choice of two heating methods: Direct steam or steam generator Automatic door operation Full range of options and accessories (see page 18 for details) Custom built units available to meet your exact requirements Image shown features optional custom glove box attachment for illustration purposes. Specifications Models listed below are a representative selection. Please contact us for the full range of available sizes and options. Model no. Volume (litres) Doors Steam generator Chamber dimensions Overall dimensions AVD250 250 2 24kW 500 x 500 x 1000 1300 x 2000 x 1395 AVD360 360 2 24kW 600 x 600 x 1000 1500 x 2000 x 1285 AVD490 490 2 48kW 700 x 700 x 1000 1500 x 2000 x 1300 SVD875 875 2 72kW 700 x 1000 x 1250 2000 x 2000 x 1650 SVD1200 1200 2 72kW 600 x 1000 x 2000 2000 x 2000 x 1395 (Overall dimensions may vary with the configuration and addition of certain options) Standard safety features Double Door SQUARE range autoclaves are fitted with the following built-in safety features as standard: Over temperature protection, a cooling lock, a safety valve test program and emergency stop button The door mechanism is safety linked meaning a cycle cannot start until the door is properly closed; or opened until the pressure and temperature within the chamber is at a safe level The door seal is steam and vacuum resistant, and will seal effectively without trapping or entrapment of foreign material Doors are thermally insulated to prevent the surface temperature presenting a potential hazard to operators Water conservation re-circulation system minimising water usage Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 17

SQUARE MAX Autoclave/Double Door Autoclave Range Advanced options (Selection of these options may alter the power supply requirements listed below) Sg Vac Jac Integral Steam Generator Option Available as 24kW, 48kW or 72kW integral steam generator. This option helps to improve cycle times by increasing the efficiency of steam production and also includes automatic water filling as standard, removing the requirement of manually filling the machine with water between sterilization cycles (a mains water supply is therefore required for this option). Astell Ref: 24KWSG, 48KWSG or 72KWSG. Advanced Vacuum Option A vacuum option is essential for porous type loads (e.g. wrapped instruments and fabrics) or other cycles where air pockets could easily become trapped within the load. The AVC001 option is Astell s advanced pulsar vacuum, which when used in conjunction with the integral steam generator and a heated jacket enables the dry output of all loads. Astell Ref: AVC001. External Jacket Option Requiring a steam generator or direct steam option. The external jacket option effectively adds an additional layer to the outside of the autoclave chamber. This can then be independently heated by the steam generator to enhance the drying process at the end of the cycle, or it can be flooded with water during cooling to aid faster cooling times. Astell Ref: AJP100 or AJP152. Additional options Integral data printer Ref: AAR130 Drain Cooling Ref: AAN420 Load Sensed Process Timing Ref: AAR014 Category III (BSL-3) compliance Ref: AVQ006 Remote maintenance/diagnosis Ethernet interface IQ/OQ documentation Ref: RDM101 Ref: AAR122 Ref: IQ/OQ Morrison discard container (W:300 x H:300 x D:300mm) Additional shelf Ref: AAQ300 Ref: AAQ801 Internal convection cooling Ref: AAP102 Water softeners Ref: AAW002 Deluge cooling Ref: ADA100 Blow down vessel Ref: SPL285 Air ballast (requires compressed air) Ref: AVC004 Loading systems Ref: AAQ600/2 Integral air compressor (Req. for Vacuum units) Ref: AAQ503 Stainless steel pipework (primary) Ref: SPL430 SPF seal (for double door machines only) Ref: AVQ007 Stainless steel pipework (full) Ref: SPL422 See pages 20-25 for further information explaining options and accessories Installation requirements Power requirements: The power requirements for the standard machines listed in the Specifications table are 415V, 3 Phase, with Neutral and Earth. Requirements can vary depending on the configuration and options selected. For additional details of exact power requirements please contact us. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (54mm diameter) capable of withstanding temperatures up to 100 C. Low water and power consumption Touchscreen controller Stainless steel pipework (optional) Pressure gauge 18 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Touchscreen controller Astell s fully programmable 5.7 colour touchscreen controller is standard fitment to all our sterilization devices All Astell Scientific autoclaves, steam generators and effluent decontamination systems incorporate the latest innovations in control system technology, providing colour touchscreen controllers as standard throughout the range. Astell colour touchscreen control systems are an advance in sterilization control technology. Bringing together years of unrivalled experience, we have produced a user friendly, fully automatic control system designed to meet and exceed the expectation of the most demanding laboratories and centres of sterilization. The controller consists of a wipe clean touchscreen measuring 122 x 94mm and is based on an industrial PLC system, combined with a number of analogue and digital input/output modules. The controller software has been developed by Astell for the precision control of all our autoclaves and sterilizers. Specifications Icon driven menu system Simple cycle selection Continual cycle monitoring Secure Data archiving for up to 5,000 cycles Multiple user access levels and multi-level password protection User log Flexible Ability to program up to 50 cycles Program new cycles, modify, duplicate or rename existing cycles Delayed start facility Hold warm facility (if applicable) Informative Digital display of pressure / temperature Cycle counter, stage timer, cycle timer and stage display Print any cycle from the data archive logs (printer required) Supportive Fault diagnosis Safety valve test cycle Machine service timer Fault history log Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 19

Autoclave options and accessories explained Integral data printer Ref: AAR130 This printer provides a permanent and traceable record of: time, temp., pressure, batch number and cycle time. There is also provision for operator signature. The printer also provides reports of cycle settings and servicing information. Load Sensed Timing Ref: AAR014 Load sensed process timing allows the sterilization cycle to be controlled via the temperature achieved in the centre of the load. This is achieved by locating a wandering probe in to a media bottle or in to a reference bottle during the sterilization cycle. Remote maintenance/ diagnosis Ref: RDM101 This option allows remote access to the touchscreen controller for diagnostics, software updates and secure data capture (additional subscription fees may apply). Ethernet interface Ref: AAR122 The Ethernet option allows the user to display the touchscreen of the autoclave on a PC and then monitor cycle progress via VNC, as well as save cycle logs to a server directly or over FTP for backup. IQ/OQ documentation Ref: IQ/OQ Typically a requirement of pharmaceutical companies or those providing medical devices/ products. The IQ/OQ provides documentary evidence that the autoclave complies to the customer s requirements (as ordered) and performs correctly. Full details available upon request. Air ballast Ref: Varies by model Provides controlled chamber pressure during the cooling phase, preventing boil over of bottled fluids. This option when combined with jacket cooling offers significant reductions in cooling times compared to standard cooling. NB. This option must be ordered in conjunction with Load Sensed Timing. Autofill Ref: AAP019 The Autofill options automatically maintains adequate water level within the chamber (for heaters in chamber models only). The water inlet is controlled by a level switch and complies with water bylaw regulations. The unit is readily connected to the water supply via a 1.5m flexible hose (supplied). Drain cooling Ref: AAN420 The exhaust heat system reduces the temperature of water sent to the drain by thermostatically controlling the temperature of any discarded water. It s ideal in situations where heat resistant drains are not present. NB. This option requires a mains water supply. 20 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Shelf options Ref: Varies by model Various shelf options are available for all front loading Astell autoclaves. All front loading units come with a base shelf as standard, but a central shelf can also be added, creating greater flexibility in terms of available sterilizing space. Top shelves are also available. Morrison discard containers Ref: Varies by model Various size morrison discard containers are available for both top and front loading autoclaves. Pictured: AAN346 AAN342 AAQ300 Water softener Ref: AAW002 Recommended to reduce the build-up of limescale on heaters and pipework etc., and particularly recommended for units with steam generators. Unit includes a separate brine tank, allowing installation in difficult or restricted positions. Requires salt. Full details available on request. Air compressor Ref: AAQ503 A supply of compressed air is essential on all vacuum units/ square section autoclaves, and units with Air Ballast fitted. The air supply is required to operate the pneumatic valves used in conjunction with the touchscreen controller. This option is therefore essential where an on-site supply is not available. Category III filter Ref: AVQ006 Category 3 compliance is often required when dealing with high risk sterilization requirements. A bacterial retentive filter fitted onto the exhaust ensuring nothing leaves the chamber without being sterilized. NB. Filter may vary from that pictured. Stainless steel top loading unit baskets Ref: Varies by model Various size stainless steel wire baskets are available for top loading autoclaves. Pictured: The AAN058 large stainless steel wire basket for the AMA250, AMA260 and AMA270. Half depth baskets are also available. Blow down vessel Ref: SPL285 This option allows the operator to expel, at high pressure, the contents of the steam generator into this specially designed vessel. The regular action of blow-down reduces the build-up of dissolved solids, elongating the life span of the generator and its heaters. In the absence of a blow down vessel, adequate, safe provision should be made for blowing down. Loading system Ref: AAQ600/2 Loading systems are available for single or double door SQUARE range autoclaves. The external trolley is manufactured from powder coated mild steel, with stainless steel runners to accept the internal stainless steel truck. Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 21

Steam Generators explained Heaters in Chamber Heaters in Chamber is the standard configuration fitted to all circular chambered Astell autoclaves and some square chambered models. On standard machines, water is manually poured by the user directly into the chamber before each cycle begins. As the heater element(s) reach temperature, the water in the chamber boils to produce pressurised steam to force the air out from the chamber. An Autofill option is available to allow automatic water filling to take place so that the autoclave does not need to be manually filled between cycles. This option is not suitable for sterilization cycles where drying is required for porous loads/fabrics. Steam Generator Steam is produced by a separate integral generator which replaces the heating elements in the chamber and gives improved control over steam production. A mains water supply enters the steam generator, where it is heated and converted to steam. This then enters the chamber directly from the steam generator as and when it is required. Please note: Direct steam models are available for most autoclaves on request for use in situations where an in-house steam supply is available. Please contact us for more information. Steam Generator 22 Astell Autoclave and EDS Product Guide

www.astell.com Cooling options explained Note: Please refer to individual ranges for the compatibility of cooling options The cooling of an autoclave load following sterilization will often be the most time-consuming stage of the cycle, particularly if bottled media (or other fluids) are being sterilized. For safe fluid sterilization, the load temperature needs to fall to 80 C before the door can be opened. With a large load of bottled media, this could mean that the cooling time will represent up to 50% of the overall duration of the cycle. For this reason, Astell offer a variety of cooling options to improve the efficiency (and therefore reduce costs) in the busy laboratory. 1 2 External Fan Cooling A powerful, externally mounted fan helps to reduce cool down time. Like all Astell s cooling options, operation of the external fan system is controlled via the colour touch screen controller. This option is available on all models (except for those fitted with a cooled or heated jacket). Water Cooling (Coils) Water is circulated through cooling coils in direct contact with the outside of the autoclave chamber, resulting in a substantial reduction of cooling time. 1 2 3 4 5 6 Autodrain For use in Heaters in Chamber autoclaves only. This feature can be selected on any cycle and will substantially decrease the time required to cool the chamber to a temperature where the door can be safely opened, especially when used in conjunction with the Water Cooling (Coils) or External Fan Cooling. At a preselected pressure during the cooling phase of the cycle, any remaining water in the chamber is evacuated to the drain. Water Cooling (Jacket) This option quickly and effectively cools bottled media and other fluid loads. After sterilization water is circulated in direct contact with the outside of the autoclave chamber, resulting in the rapid decrease of the internal chamber temperature. The effectiveness of Jacket Water Cooling can be further enhanced if the autoclave is fitted with Internal Fan Cooling (see below for details). Please see page 24 for details of how to eliminate Boil Over when using this cooling method. Cyclon Cooling Cyclon Cooling provides major benefits in laboratories where large quantities of culture media need to be processed quickly as it provides a significant reduction in cycle time. This option in itself is available free of charge, however as a prerequisite, Water Cooling (Jacket) and Air Ballast options are both required. This method of cooling is ideal for use in situations where large loads of bottled fluids (e.g. culture media) need to be sterilized quickly. Internal Fan Cooling A magnetically driven internal fan is situated in the chamber itself, which creates turbulence. The fan needs to be fitted in conjunction with Water Cooling (Jacket) in order to be effective, and these combined options provide one of the most efficient ways of cooling the chamber and load. The dual system is therefore ideal in situations where large fluid loads need to be processed as quickly as possible. Internal Fan Cooling, when used in conjunction with Water Cooling (Jacket), Air Ballast and Load Sensed Timing makes cooling times up to 70% faster than a standard autoclave fitted with no cooling system. Air Compressor Drain 3 4 5 6 Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 23

Air Ballast and Load Sensed Timing explained Cooling fluids quickly and safely Figure 1.1 How can I quickly and efficiently sterilize fluid loads? Sterilizing fluid loads in a quick and effective manor is something that can be easily achieved by using the right options. All Astell autoclaves can be used to sterilize fluids, but to sterilize fluid loads quickly the addition of a Cooling system and Air Ballast must be used. What is Load Sensed Timing? Load Sensed Process Timing allows the sterilization cycle to be controlled directly by the actual temperature of the load rather than just the chamber temperature. A flexible sensor probe (pictured right) is fitted inside the autoclave chamber and the user should submerge the probe directly into the media (or a reference bottle). It is recommended this is placed in the centre of the autoclave, or the coldest spot (usually determined using validation). By selecting one of the pre-set sterilization cycles via the touch screen controller, the user can then ensure that sterilization does not begin until the very centre of the load has reached the correct temperature. But why is Air Ballast required? Figure 1.1 shows how most autoclaves would operate when no assisted cooling is used. This can be a long process, as after sterilization the chamber must cool down naturally to a safe temperature. However, in circumstances where a rapid cooling system is used, the sudden change in pressure will most likely cause media/fluids to boil over rendering the samples useless and creating spillage in the autoclave chamber (as is illustrated in Figure 1.2). Figure 1.2 Figure 1.3 Load Sensed Process Timing Water Cooling (Jacket) The best solutions to avoid the problem displayed in Figure 1.2 (whereby boil over occurs when the chamber is suddenly cooled) are as follows: Air Compressor Solution One Advantage Cost effective cooling for standard loads If assisted cooling is used (i.e. an External Fan, Water Cooling (Coils) or Jacket Cooling) the cooling would normally be set to activate at just above 100 C to stop a rapid drop in the chamber pressure. Whilst this means there is a delay between sterilization completion and the start of the cooling process, it ensures there is a reduced risk of media/fluids boiling over and emptying into the chamber. Solution Two Advantage Fast efficient cooling (when required) The second way is to use Air Ballast. Compressed air is quickly injected into the chamber to replace the steam used during sterilization and maintain the chamber pressure during the cooling phase. By using a compressed air source, or an air compressor (available separately), the cooling process can begin immediately following sterilization. The Air Ballast function controls the internal chamber pressure whilst at the same time allowing the selected cooling method to cool the load. This combination of these two processes ensures a controlled and quick cooling process. If this is then coupled with Fan Cooling (Internal to the chamber) it provides one of the fastest cooling methods available for non-sealed fluid loads. 24 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Simple and Advanced Vacuum explained Improved air removal for difficult loads Simple Vacuum Pre and Post Vacuum with Cooling Astell s Simple Vacuum system is ideal for situations where improved air removal from difficult loads is required. It is ideal for dense discard loads, or vacuum cooling of unwrapped items. (i.e. beakers, plastic containers, metal instruments or glassware). A typical cycle begins with a pre-vacuum, reducing the chamber pressure and removing the majority of air. A free steaming (air purge) stage then begins. After the sterilizing stage is complete, water in the bottom of the chamber is expelled and then a post vacuum takes place, removing any remaining steam from the chamber and cooling the load. Whilst this method of air removal is much more effective than a standard autoclave without vacuum, items which retain water i.e. fabrics or porous items should be sterilized using the Advanced vacuum method. Vacuum Pump Advanced Vacuum Pre Vacuum with Negative and Positive pulses and Vacuum drying* Advanced Vacuum is often preferable when dealing with wrapped instruments, porous loads or fabrics typically found in dental, hospital and medical applications. A typical cycle starts with a pre vacuum which is followed by negative and positive steam pulses; by far the best method for removing air from porous loads and discard waste. Following the sterilization stage, a post vacuum removes the steam from the chamber. In combination with the heated jacket option, a drying stage then begins to ensure loads are touch dry upon removal. *requires Heated Jacket and Steam Generator Heated Jacket Why is a Steam Generator and Heated Jacket required? In order to ensure a touch dry load is achieved, the condition inside the autoclave need to be just right. with the Advanced Vacuum, negative and positive steam pulses from a dry saturated steam source (i.e. a Steam Generator) to provide the perfect air removal, sterilization and drying conditions. Achieving touch dry loads is not only achieved with the Advanced Vacuum, but also by using a steam source external to the chamber and a Heated Jacket to avoid cold spots within the autoclave chamber. This then means that as steam enters the autoclave and comes into contact with the chamber wall, the steam does not condense and produce a wet environment. At the end of the cycle a vacuum is pulled on the chamber, removing the remainder of the steam within the chamber and leaving the contents touch dry. Vacuum Pump Steam Generator Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 25

Service and Maintenance Astell are able to offer servicing contracts for all the equipment we manufacture At Astell Service we are proud to support you with the long-term use of your Astell autoclave by offering a full range of products and services, ensuring the most reliable autoclaves on the market are Astell autoclaves. We offer the full flexibility of allowing the selection of one of our standard Routine Preventive Maintenance contracts, or working with you to design the support that you require, that best suits your site, through to custom-built plans that could include comprehensive maintenance support covering parts and labour, UKAS accredited calibration, multi-point validation and operator training. Our standard range of services include fixed term contracts with either 1, 2 or 4 RPM visits per annum that benefit from the experience of our factory trained Field Service Engineers, discounts on un-scheduled site visits during the term of the contract, discount on spare parts and consumables required during the term of the contract, free delivery on all orders over 250.00, and no minimum order value. Please contact Astell Service for further information and advice. Validation and Calibration Astell Service are able to offer UKAS accredited calibration and validation services conforming to ISO 17025:2005 through our team of factory trained and fully equipped Field Service Engineers, ensuring each appliance is accurate, trusted and meeting your protocol requirements (protocols can be written to customer requirements subject to the specification of the appliance). We support document packages for Installation Qualification (IQ) and Operational Qualification (OQ) together with a full multi-point validation service for Performance Qualification (PQ) resulting in a clear and concise documented history of your appliance performance. Technical Support Astell Service can offer technical support both on and off site through our knowledgeable team. We will happily receive your enquiry via the web-site, telephone or email E-mail: service@astell.com Telephone: +44 (0)20 8309 2000 In a recent customer survey the helpfulness of Astell Engineers was scored at 98.5% 26 Astell Autoclave and EDS Product Guide

www.astell.com Steam Generator Range 24kW, 48kW and 72kW models Stand-alone steam generator units Astell s Steam Generators are fully programmable via the touchscreen controller, giving constant information regarding: pressure vessel status, pressure/water level, pump status, time/date, running/tripped status, low water alarm, programmable working pressure and a graphical display of water level and steam pressure. A password protected control system allows instant access, including manual control and full override. Standard features include: Electrically heated & capable of clean steam generation (subject to water supply) Touchscreen controlled with high/low water level indicator Electropolished stainless steel pressure vessel Over temperature and over pressure cut out Float switch level control (water) Stainless steel pipework, panelwork and a sight glass are available as optional extras in addition to the above specification of the standard unit. STG024/STG048 model Specifications Model no. Rating No. of heaters Power supply Width (mm) Height (mm) STG024 24kW 1 3 Phase + Neutral & Earth, 24kW 600 1280 1060 STG048 48kW 2 3 Phase + Neutral & Earth, 48kW 600 1280 1060 STG072 72kW 3 3 Phase + Neutral & Earth, 72kW 800 2000 1150 Depth (mm) Technical details STG024/ STG048 STG072 Water capacity 89 litres 292 litres Working water level 68 litres 168 litres Max. working pressure 6 Bar 6 Bar Installation requirements Power requirements: The power requirements for the standard machines listed in the Specifications table are 415 V, 3 Phase, with Neutral and Earth. Requirements can vary depending on the configuration and options selected. For additional details of exact power requirements please contact us. Water and drainage requirements: A cold water supply of 2-6 Bar minimum, 4 litres/min is required. Max temperature 25 C, Max flow rate 20 litres/min. Requirements vary for RO/de-ionised/hard water. Drainage: Free venting, non-manifolded drain (54mm diameter) capable of withstanding temperatures up to 100 C. STG072 model Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 27

Effluent Decontamination Systems Batch sterilization for BSL3 waste Designed to your requirements Astell Scientific manufactures a wide range of aqueous liquid Effluent Decontamination Systems (EDS) to service any BSL3 facility. EDS are particularly suitable for high containment facilities or high risk laboratories. As no two projects are likely the same, Astell offers comprehensive project management to guide you through the consultancy stages, including but not limited to: Site surveys/technical advice and specifications Detailed proposals and technical diagrams Manufacturing Delivery and installation Validation testing IQ/OQ packages (installation/operation qualifications) What waste can be treated? Effluent types vary for each project, but typically treatable effluent sources will include: Tap water from sinks and wash basins Water from washroom facilities within a containment area Sanitary installations such as toilets Water from showers and other cleaning facilities in the containment area Any exhaust/water from sterilizers used within the BSL3 area Standard features Colour touchscreen controllers Analogue jacket and chamber gauges Double valving on effluent input Manual override Jacket heating and cooling Stainless steel vessels (grades available) Pumped or non-pumped systems Integral or external steam supply Fully demountable for easy shipping and install Radar level controlling for accurate tank level monitoring Steam sterilizable retentive bacterial filter (1 per chamber) Inspection hole Primary stainless steel to first valve pipework Special design to eliminate the need for safety valves on the sterilizing chamber Options and upgrades Remote technical support unit (contact us for details) Higher grade vessel material for special applications Internal heating and cooling coil to improve cycle times Double valving on all valves Hygienic instrumentation Cooling water recirculation to reduce water consumption Agitation to provide better heat distribution and distribute solids Valve position monitoring Full stainless steel pipework 28 Astell Autoclave and EDS Product Guide Tel: +44 (0)20 8309 2031

www.astell.com Nelldorn Glassware Dryer An economical and efficient method of drying and storing most containers, glassware and plasticware The Nelldorn Dryer provides an economical and efficient method of drying and storing most containers, glassware and plasticware. In the laboratory, volumetric flasks, measuring cylinders, test tubes and similar equipment can conveniently be dried then left on the tubes until required. For pharmacies the unit can be used for most types of dispensing containers including plastics. Features include: Capable of holding up to 60 items with 15-20min drying times Wall mountable or free-standing Thermostatically controlled Economical, quick and efficient Units come complete with a variable 120 minute timer and can dry up to 60 items at one time. A large volume of air is drawn over the thermostatically controlled heating elements and forced through each drying tube. The rapid flow of air dries glass or plastic quickly and without any damage to the apparatus. The Nelldorn Dryer also has a very low power consumption, so is considered more economical to run than a traditional oven dryer. Drying tube capacity The table below refers to tube length against drying capacity. 75mm 100mm 140mm 152mm 30 13 9 8 Specifications Model: DCU012 Voltage: 220/240V, 13A Dimensions: Width 490mm x Height 430mm x Depth 190mm Space saving design The stepped design allows the removal of any item without disturbing the remainder of the load. This also facilitates the run off of water to the front of the unit where a small drain pipe prevents it collecting at the base. The air intake is recessed at the back of the unit to allow wall or bench mounting. The dryer is fitted with 60 rigid stain resistant nylon drying tubes with an adjustable timer which can be preset to switch off at your desired time (max 120 mins). Tel: +44 (0)20 8309 2031 Astell Autoclave and EDS Product Guide 29