PHARMACEUTICAL LIFE SCIENCE SOLUTIONS

PHARMACEUTICAL LIFE SCIENCE SOLUTIONS Model Ranges: Cryogenic Freezers TwinGuard ULT Freezers VIP ECO ULT Freezers Biomedical Freezers MPR Pharmaceutical Refrigerators IncuSafe CO 2 & Multigas Incubators MIR Heated and Cooled Incubators PHCbi Biomedical products are designed to meet the demands of the pharmaceutical & biotechnology industries providing reliability, accuracy, and sample security to facilitate cuttingedge research and drug discovery. www.phchd.com/eu/biomedical

PHCbi Pharmaceutical Solutions offer: Precise uniformity Temperature stability Quiet, reliable compressors Sample safety Energy savings Alarms & monitoring Ergonomic design Service and support 2

Innovative solutions for the Pharmaceutical Industry Table of contents Best storage temperature uniformity Step into the world of validation 8 3 Find the right laboratory equipment for your needs 4 Cryogenic Freezers (50ºC) 6 Isothermal Freezers (90ºC) 7 TwinGuard and VIP ECO ULT Freezers (86ºC) 8 Biomedical Freezers 2 MPR Pharmaceutical Refrigerators 3 MPR Pharmaceutical Refrigerators with Freezer 3 IncuSafe CO 2 & Multigas incubators 4 MIR Heated and Cooled Incubators 7 Validation 24 3

Find the right laboratory Cryogenic Freezers 50ºC / 52ºC Ultralow Temperature Freezers TwinGuard ULT Freezers 86ºC ULT Freezers Biomedical Freezers 30ºC / 40ºC Freezers The most uniform storage temperatures for cryopreservation solutions The safest ultralow temperature freezers for the storage of high value samples Stable environment with extensive storage possibilities No cross contamination. Safe and convenient usability. Specially designed cascade refrigeration system. Low operational costs. VIP PLUS vacuum insulation maximises storage capacity. Dual Cooling refrigeration system for ultimate sample protection. Intelligent 'ECO mode' operation results in lower running costs. Vacuum release port for improved accessibility. VIP PLUS vacuum insulation maximises storage capacity. Low running costs. HC Refrigerants provide more efficient cooling due to a high latent heat of evaporation. Direct cooling system for uniform temperature control. Fullheight storage containers on each shelf. Low environmental impact. 4

equipment for your needs MPR Pharmaceutical Refrigerators Uniform storage temperature for the most demanding applications IncuSafe CO 2 & Multigas incubators Incubators from 49 litres to 230 litres Optimising cell culture outcomes and reproducibility IncuSafe CO 2 Reachin Incubator 85 litres Largescale cell culture CO 2 Incubator Available in a range of sizes and with swing or sliding door options. Excellent temperature stability and uniformity. Wide temperature range. Powerful and responsive refrigeration system. Integrated shelfsupports. Fullcolour LCD touch screen. USB port. Excellent control of O 2, CO 2 and temperature. Dew stick prevents condensation. Removable, easytoclean, humidifying pan. Certified as a Class IIa Medical Device. Superior temperature and CO 2 control. Rapid recovery times. Exceptionally low CO 2 consumption rates. Reachin design with large, 85litre capacity. 5

Models: MDFC256VANPE I MDF56PE Cryogenic Freezers Cryogenic Freezers are wellknown for maintaining uniform temperatures at 50ºC for the reliable, longterm preservation of cells and tissues. With thin vacuum insulation panel (VIP) walls, the MDFC256VAN Cryogenic Freezer can achieve more storage capacity than a conventionally insulated freezer without increasing footprint, while also maintaining superior temperature uniformity. CROgENIC FREEzERS PROMOTE SAMPLE STABILITy A uniformity of +/5ºC in our mechanically refrigerated Cryogenic Freezers is far superior to the toptobottom temperature uniformity provided by liquid nitrogen vapour phase storage, without the concern of crosscontamination often associated with liquid nitrogen (liquid phase storage). Recrystallization mechanism 80ºC 30ºC Recrystallization Point 50ºC Hexagonal crystal Cubic crystal Amorphous ice crystal Model: MDFC256VANPE Liquid Nitrogen freezer (Traditional vapour phase) MDFC256VAN mechanically refrigerated Cryogenic Freezer Comparison of temperature distribution in a liquid nitrogen freezer (vapour phase) and PHCbi s MDFC256VAN mechanically refrigerated Cryogenic Freezer. The graph shows temperatures at different locations within the chamber. This data demonstrates that 00% of the MDFC256VAN storage space maintains uniform storage temperatures safely below 30ºC, while temperature in the LN 2 vapour system is dependent on storage location. 6

Models: CBS Isothermals CBS Isothermals PHCbi also offers Isothermal Carousel Liquid Nitrogen Vapor Storage system which combines the innovative 90ºC isothermal design with a small opening and an interior rotating carousel. The system has a small opening which helps to reduce liquid nitrogen consumption, ensures the lid is both lightweight and userfriendly and keeps temperatures in the freezer consistently low. With improved operation and design, the system provides superior temperature uniformity for maximum sample preservation. In addition, a unique patented liquid nitrogen jacket allows samples to stay cool without coming into contact with liquid nitrogen. Model: V3000AB/C Standard square rack configuration V500AB Vacuum insulation Temperature controlled storage area Model: V5000EH AB/C Liquid nitrogen envelope KE ADVANTAGES ) Dry storage freezer. 2) Unique patented liquid nitrogen jacket allows for no liquid in sample storage space and improves user safety. 3) Reduced exposure to room temperatures. 4) Superior temperature uniformity. 5) No risk of crosscontamination through liquid nitrogen contact. 6) Carousel is rotated from outside of the freezer eliminating risk of injury or temperature fluctuations. 7) Manufactured to ISO 3485 standards. 7

TwinGuard ULT Freezers TwinGuard Ultra Low Temperature Freezers with Dual Cooling Technology offer the highest level of security for highvalue samples. Alongside exceptional easeofuse and data monitoring, the Dual Cooling System provides the highest level of protection through the use of two independent refrigeration systems. If one system unexpectedly fails, the other can maintain the freezer s temperature uniformly in the 70 C range. Developed for use with conventional inventory racks and boxes, the TwinGuard Series is ideal for storage of sensitive, highvalue samples. SCIENTIFIC APPLICATIONS Temperature sensitive samples such as therapeutics and biospecimens. Samples needing to retain viability such as stem cells, engineered tissue, organs, vaccines, hybrodmas, cancer cells or fibroblasts. Longitudinal study samples. Important medical research samples. Valuable pharmaceutical products. Clinical trial samples. Pathogenic samples within high security laboratories. MDFDU502VX, MDFDU702VX, MDFDC500VX and MDFDC700VX Freezers are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of storing cells, tissues, organs and embryos. Model: MDFDC700VXPE Model: MDFDU702VXPE 8 Models: MDFDU702VX MDFDU502VX

Models: MDFDU502VXPE I MDFDU702VXPE I MDFDC500VXPE I MDFDC700VXPE PRESERVE SAMPLE INTEGRIT FOR BETTER END PRODUCTS (TwinGuard) Uneven interior temperatures can lead to a loss in sample integrity. Freezers with uniform, stable temperatures and quick recovery times provide the best protection for your samples, ensuring reliable preservation while guarding against degradation. FIGURE 2A MDFDU702VX; 9 POINT TEMPERATURE MAPPING TwinGuard DUAL COOLING SSTEM Within TwinGuard's refrigeration system, efficient ultralow cooling is achieved through two independent evaporator circuits surrounding the interior chamber. Two independent evaporator circuits 86ºC ENHANCED USE & INTELLIGENT SECURIT The freezers are managed and monitored by an integrated microprocessor controller with a comprehensive alarm system and diagnostic functions. Status and control of parameters are accessible via an LCD information centre. The EZlatch, on the upright models, makes access to stored samples even easier. A colour LCD touch panel allows full user control, even with gloved hands, while the USB port makes transferring logged data to a PC convenient. A B FILTERLESS DESIGN The filterless construction of the freezers reduces routine maintenance time by eliminating the need for regular cleaning of filters. Dual Cooling System Upright freezers The Dual Cooling System offers the highest level of security through the use of two independent refrigeration systems. If one system unexpectedly fails the other can maintain the freezer at the 70 C range. SUPERIOR FOOTPRINT TwinGuard UltraLow Temperature Freezers with spacesaving VIP insulation deliver exceptional cooling performance and durability for storing valuable research and clinical samples. 9

Models: MDFDU502VHPE I MDFDU702VHPE VIP ECO ULT Freezers VIP ECO Ultra Low Temperature Freezers with natural refrigerants minimise energy consumption, reduce environmental impact and save money. Innovative technology and Class IIa Medical Device Certification provide secure storage of valuable research and clinical samples. The VIP vacuum insulation ensures an optimal footprint to storage capacity ratio. The VIP ECO ULT Freezers use vacuum insulation panel (VIP) technology reducing wall thickness by around 50%, achieving 30% more storage capacity, and reducing the average cost per box stored. Leveraging the power of natural hydrocarbon refrigerants also allows the VIP ECO ULT Freezers to use smaller compressors, and reduce energy consumption. The natural hydrocarbon refrigerants combined with VIP insulation technology also help the environment by reducing the carbon footprint with up to 40% fewer emissions. MDFDU502VH and MDFDU702VH Freezers are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of storing cells, tissues, organs and embryos. Model: MDFDU702VHPE REDUCED RUNNING COSTS VIP ECO Ultra Low Temperature Freezers, with reduced power consumption, have the benefit of much lower running costs. They also dissipate less heat, reducing air conditioning requirements for further cost savings. ) Model MDFDU702VHPE (728 litres) compared to MDFU73V at set value 80ºC, 23ºC ambient, no load, 230V 50Hz, 0.2/kWh. Actual energy use and savings will depend on operating conditions and price of electricity paid. 2) Model MDFDU502VHPE (526 litres) compared to MDFU53V at set value 80ºC, 23ºC ambient, no load, 230V 50Hz, 0.2/kWh. Actual energy use and savings will depend on operating conditions and price of electricity paid. Consumed Power (kwh/day) MDFDU502VH up to 55% more efficient MDFDU702VH up to 46% more efficient MDFDU502VH Up to 5.000 savings on energy costs over 0 years ) MDFDU702VH Up to 4.400 savings on energy costs over 0 years 2) *MDFDU702VH compared to existing PHCbi models of equivalent size. EXTREMEL LOW ENVIRONMENTAL IMPACT Naturally occurring hydrocarbon (HC) refrigerants used within the VIP ECO ULT Freezers are non ozone depleting, have short atmospheric lifetimes and have extremely low global warming potentials (gwp's). This makes the freezers very environmentally friendly so they are an ideal solution for complying with objectives for reduced carbon footprints. 0

Models: MDFDU900VPE VIP ULT Freezers VIP ULT Freezers represent an industry leading combination of refrigeration, control, alarm, monitoring and accessibility for reliable sample preservation. WHICH FREEZER WILL OU CHOOSE? EFFICIENC HIGHEST BOX CAPACIT The use of highly efficient VIP PLUS insulation optimizes interior volume in the smallest footprint possible. This ensures the most efficient use of space for up to 40%* more 2 box storage capacity within the same footprint. 668 litres capacity up to 480 x 2 boxes 845 litres capacity up to 672 x 2 boxes *MDFDU900VPE compared with PHCbi model with an equivalent footprint Conventional Freezer VIP ULT Freezer With VIP Insulation EZlatch The EZLatch door handle on the MDFDU900V makes access to stored samples even easier. Designed to open with minimal effort and repeatedly stress tested to ensure endurance. Model: MDFDU900VPE

Models: MDFU73MPE I MDFMU300HPE I MDFMU500HPE Biomedical 30º / 40ºC Freezers HIGH PERFORMANCE FREEZERS WITH OPTIMAL TEMPERATURE UNIFORMIT The Biomedical Freezers are designed for long or intermediateterm storage at temperatures as low as 40ºC. Constructed with timetested laboratory and clinicalgrade refrigeration systems, these freezers are ideal for the storage of a wide variety of samples including enzymes, biologics and medicines. RAPID TEMPERATURE RECOVER MAINTAINS UNIFORMIT The rapid pulldown speeds of our Biomedical Freezers ensures that the effects of door openings are minimized. Uniform temperatures are maintained throughout the chamber through direct cooling. The inner chamber temperature offers outstanding uniformity and stability without temperature spikes. Sample storage Microprocessor controls: Configure temperature setpoints, alarms, monitoring, and diagnostic functions through a digital display. 2 freezer bins: For all 30ºC & 40ºC freezers a wide variety of storage solutions are available. From shelves to racks and / or bins. 2 Model: MDFU73MPE 2

Models: MPR72PE I MPR72RPE I MPR4PE I MPR4RPE I MPR75FPE MPR Pharmaceutical Refrigerators MPR PHARMACEUTICAL REFRIGERATORS OFFER A COMPLETE SOLUTION FOR THE MOST DEMANDING REQUIREMENTS FOR STORAGE OF PHARMACEUTICALS, MEDICINES, VACCINES, AND OTHER TEMPERATURESENSITIVE APPLICATIONS. MPR Pharmaceutical Refrigerators are specially designed to comply with pharmaceutical regulations. Exceptional temperature uniformity is paired with easy calibration access to meet critical validated storage regulations. A thermistor sensor monitors temperature inside the chamber, while microprocessor controls ensure that an accurate set temperature is maintained. Even with frequent door openings, the circulation fan provides rapid temperature recovery for a stable preservation environment unaffected by ambient temperature. Adjustable shelves (MPR72/4) The height adjustable shelves can be arranged to accoodate a variety of sample types and specimen racks. 2 Drawer type (MPR72R/4R) The R models are fitted with pullout drawers. With a profile of 00 and 530 front to back, these drawers are deep enough to hold large bottles or reagent kits. They also allow convenient, spaceefficient storage and management of patient medications and other items. 2 Model: MPR75FPE Model: MPR4RPE A COMPLETE STORAGE SOLUTION: REFRIGERATOR AND FREEZER IN ONE UNIT. The MPR Pharmaceutical Refrigerators with Freezer combine high performance refrigeration with a 30ºC freezer environment in one unit. These models feature dual temperature zones that are provided by separate refrigeration systems for fridge and freezer section. The multidoor design reduces temperature fluctuation during door openings. 3

Models: MCO70AICPEseries I MCO230AICPEseries I MCO80ICPE I MCO70MPEseries IncuSafe CO 2 & Multigas Incubators IncuSafe CO 2 & Multigas Incubators, with innovative technologies, offer outstanding quality in performance to maximise cell culture productivity and provide optimum results with reproducibility to meet the demands of todays varied cell culture applications. ACTIVE BACKGROUND DECONTAMINATION During cell culture, incusafe and SafeCell UV actively prevent contamination The exclusive incusafe copperenriched stainless steel alloy interior offers the germicidal properties of copper and the durability of stainless steel. The optional, isolated, SafeCell UV lamp decontaminates circulating air and water in the humidifying pan, without harming cultured cells. Model: MCO70AICPE ULTRAVIOLET LIGHT AND COPPER ENRICHED STAINLESS STEEL INTERIOR REDUCE THE CHANCE OF CONTAMINATION To further prevent contamination in the incubator, PHCbi implemented a unique SafeCell ultraviolet (UV) system. SafeCell UV technology uses a prograable ultraviolet lamp that sterilises air and the humidity water pan without affecting cell cultures. It inhibits the growth of all contaminants including mycoplasma without costly HEPA filter air scrubbers which are ineffective on particles less than 0.3 microns. Airflow UV Light InCusaFe Interiors InCusaFe fights off surface contamination and does not corrode like solid copper surfaces Easier visibility with better looking interior Standard feature with IncuSafe Incubators at no additional cost Pure Copper Interiors Will corrode over time (humid environment turns it into green cupric oxide, which may prove to be lethal to cells) Contamination difficult to detect due to less visibility More expensive and difficult to maintain 4

CONSISTENT AND UNIFORM ENVIRONMENT FOR CELL GROWTH IncuSafe CO 2 & Multigas Incubators combines a Direct Heat System with an Air jacket heating system that surrounds the inner walls with a natural convection airflow to achieve exceptional temperature uniformity within the chamber. Combined with a dual infrared sensor for unprecedented control over CO 2 gas levels, the incubator provides a stable environment for cell growth even with multiple door openings daily. PRECISE CO 2 CONTROL & RECOVER The single beam, dual detector IR CO 2 sensor offers continuous calibration for excellent control, accuracy and stability. The sensor simultaneously measures sample and reference wavelengths for continuous autozero calibration. The ceramicbased sensor is unaffected by moderate changes in temperature and relative humidity and is linked to the P.I.D. controller for fast recovery times. ZIRCONIA O 2 SENSOR The more O 2 passes through the Zirconia sensor, the more electrical current is induced. This creates a signal to inject more N 2, for when samples require low oxygen levels or to inject more O 2 for when samples require elevated oxygen levels. CONDENSATION MANAGEMENT With a unique antibacterial coating the dew stick controlled by Peltier technology condenses water vapour on its surface, which then drips into the humidifying pan, preventing unwanted condensation in the chamber and possible contamination. Model: MCO230AICPE RAPID HDROGEN PEROXIDE DECONTAMINATION REDUCES EXPERIMENTAL DOWNTIME With our hydrogen peroxide technology, achieve complete decontamination 8X faster than conventional high heat methods. The cycle completes in just 3 hours including the final ultraviolet decomposition of H 2 O 2 into water and oxygen for easy cleanup. This allows researchers to get back to their cell culture work the same day and allows companies to achieve faster drug discoveries. HARMLESS H 2 O + O 2 SafeCell UV CONTAMINANT DAMAGE Remaining H2O2 and hydroxyl radicals CONTAMINANT CELL CONTAMINANT DEATH 2 OH OH initiates chain reaction of electron stealing H 2 O 2 separates in two hydroxyl radicals OH + OH H 2 O 2 can obtain an electron from an organic source 5

Models: MCO70AICPEseries I MCO230AICPEseries I MCO80ICPE I MCO70MPEseries IncuSafe Incubators are designed with ease of use and efficiency in mind. By delivering a user friendly cell culture incubator with responsive systems and processes we can help make your work as simple as possible. MORE SPACE FOR MORE CULTURES In a laboratory environment it is important to make the most of all the space available. With integrated shelf supports the IncuSafe MCO70AIC CO 2 incubators provide space for up to 25% more culture vessels.* * Compared to previous 70 litre CO 2 incubators. The IncuSafe Incubator design delivers exceptional ease of use, effortless maintainance, and outstanding performance with multilevel contamination control. USB PORT Optimise cell culture protocols and adhere to standard operating procedures by conveniently transferring data to a USB memory stick to pass on to a PC. Logged parameters include chamber temperature, CO 2 level, O 2 level, door open status and alarms. MEDICAL DEVICE DIRECTIVE MCO70AIC MCO230AIC MCO70M Series are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of culturing cells, tissues, organs and embryos. INTEGRATED SHELF SUPPORTS The MCO70AIC, MCO230AIC and MCO70M incubators have less removable parts than the traditional incubators. The interior design with integrated shelf supports makes it easier to clean which saves valuable time and reduces the risk of contamination. Model: MCO70AICPE 6

IncuSafe MCO80IC REACHIN INCUBATOR Sometimes your pharmaceutical research may call for large scale processing. With the IncuSafe MCO80IC large scale reachin incubator, take your cell culture needs to greater levels by growing more cell lines at once. Improved decontamination technologies (24/7 Active Bacround Decontamination control with optional UV light) and CO 2 and temperature sensors allow for faster turnaround and higher cell yield. Model: MCO80ICPE MIR Heated and Cooled Incubators Quality control and testing is an important aspect of pharmaceutical development. With our heated and cooled incubators, achieve optimal temperature configuration for a variety of protocols, including QA / QC, microbiology and stability conditioning. Models: MIR63HPE I MIR263HPE MIR54PE I MIR254PE I MIR554PE Model: MIRH63PE Model: MIR554PE 7

Validation & qualification SOLUTIONS Keeping up with evolving regulations that are constantly becoming stricter can be a daunting task. When it comes to your laboratory equipment it is important to know that it will pass compliance checks and that the manufacturer has years of experience in validation training and services. PHCbi is a vertical component manufacturer that can provide turnkey solutions for validation and qualification in accordance with all current regulations and specific customer requirements and applications. Validation Solutions Turn key solutions available for: l l l l l l l l UltraLow Freezers Cryogenic Freezers Medical Freezers Pharmaceutical refrigerators Incubators Ovens Autoclaves Environmental test chambers PHCbi VALIDATION SOLUTIONS Inhouse Third party Manufacturer Equipment experience Broad based Broad based Most PHCbi specific experience Up to date technical info General knowledge General knowledge Direct updates Unexpected service issues Time delay Time delay Iediate solutions Time consuming More prep. time More prep. time Most experience Knowledge of industry standards High level Broad based Best applicable knowledge 8

INSTALLATION AND OPERATIONAL QUALIFICATION (IOQ) PHCbi offers onsite validation of PHCbi manufactured equipment via Installation and Operational Protocol (IOQ). ) INSTALLATION QUALIFICATION (IQ) Verifies and documents the equipment installation to be compliant with the manufacturer s requirements and specifications. 2) OPERATIONAL QUALIFICATION (OQ) Verifies and documents the full functional operation of the installed equipment (as specified by PHCbi or other OEM supplied equipment). Temperature performance will be mapped over a continuous 24hr period. Data produced will be compared with manufacturer s published equipment specification. Product specific parameters such as the CO 2 /O 2, %RH, etc can be included within the relevant equipment IOQ protocol. 3) PROCESS QUALIFICATION (PQ) Usually conducted and performed by the enduser as the equipment will be in an environment where specific user conditions apply, i.e., the customer s actual production or product processing area. The PQ will make reference to customer specific Standard Operation Procedures documents (SOPs). 4) TEMPERATURE MAPPINg Offered for customers wishing to verify actual equipment performance as installed. This is also available for nonphcbi equipment. 5) FACTOR ACCEPTANCE TESTING (FAT) Indepth factory acceptance testing covers alarms, temperature and CO 2 stability, and temperature recovery. This service can be customised to SOPs. Validation by Model MDF50ºC Freezers MDF86ºC Freezers MDF30ºC Freezers MBR Blood Bank Refrigerators MPR Pharmaceutical Refrigerators MIR Incubator Series MCO CO 2 &O 2 /CO 2 Incubators MLS Top Loading Autoclaves MLR Environmental Test Chamber CBS Standard LN 2 Freezers 4 4 4 4 4 4 THERMAL VALIDATION PHCbi validation services by model We also provide a thermal validation solution specifically designed to conform with new FDA data security guidelines (2 CFR Part ) and meet international and European cgmp requirements for inspection of pharmaceutical, biotechnology, and medical device (EN285, EN554), manufacturing. INSTALLATION, CALIBRATION & MAINTENANCE In order to trace and keep an accurate record of performance of your lab equipment, a regular schedule of calibration and preventive maintenance is required. PHCbi offers the following services: Coissioning/Setup/Installation Calibration Onsite Protocol Execution Warranty response Factory Acceptance Testing Custom Validation Protocols Temp. CO 2 O 2 %RH Lighting Pressure (Lux/Par) 4 4 4 4 4 4 4 4 4 4 4 9

SPECIFICATIONS CROgENIC FREEZERS Cryogenic Freezers Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Capacity Net weight (approx) Performance Cooling performance 2) Temperature setting range Temperature control range 2) Control Controller Display Temperature sensor Refrigeration Refrigeration system Highstage compressor Highstage refrigerant Lowstage compressor Lowstage refrigerant Insulation material Insulation thickness Construction Exterior material Interior material Outer door lock Inner door/lid Max. load total Access port position diameter Casters Alarms Power failure High temperature Low temperature Filter Door open Electrical and Noise Level Power Supply Noise Level 3) Options Liquid CO 2 backup Liquid N 2 backup Temperature recorders Continuous strip type Chart paper Ink pen Recorder housing litres 2 boxes º C º C º C W W Ø db(a) MDF56PE 400 x 800 x 945 500 x 450 x 572 28 8 265 52 25 ~ 55 30 ~ 52 Microprocessor, nonvolatile memory LED Pt00 Cascade 00 HFC 00 HFC mixed PUF 75 Aluminium 300 Left 40 6 (2 levelling feet) (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR VBR VB 230V 50Hz single phase 6 CVKAT2PW 4,5) CVKATN2PW 4) MTR55HPW RP55PW DF38FPPW MDFC256VANPE 730 x 765 x 00 760 x 495 x 65 23 50 38 50 25 ~ 52 25 ~ 50 Microprocessor nonvolatile memory LCD Pt000 Cascade with autocascade lowstage 00 HFC 00 HFC mixed PUF / VIP PLUS 35 Aluminium 2 207 Right 40 6 (3 levelling feet) VBR VBR VBR VB VB 230V 50Hz single phase 5 Supplied as standard MTR55HPW RP55PW DF38FPPW MDFS3050PW ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Air temperature measured at freezer centre, ambient temperature +30ºC, no load 3) Nominal value. Bacround noise 20dB 4) Requires recorder MTR55HPW 5) CVKAPW may also be used 20

Models: MDF56PE MDFC256VANPE CBS Isothermals Isothermal 90ºC Dry Storage Freezers Model Number Liquid nitrogen capacity Dimensions External dimensions (W x D x H) Usable interior height Usable interior diameter Weight empty Weight full Maximum capacity Max. vial capacity (2ml)** Max. blood bag capacity (50ml)** litres V500AB 30 660 x 939 x 43 736 534 48 74 900 434 V3000AB 70 939 x 29 x 206 736 787 272 327 2200 20 V3000ABEH 89 939 x 29 x 473 940 787 295 367 25500 280 V5000AB 93 29 x 37x 320 736 06 425 500 40300 936 V5000ABEH 40 29 x 37 x 473 864 06 453 566 46500 2208 ** Capacity is subject to rack type Isothermal Carousel Model Number Liquid nitrogen capacity Dimensions External dimensions (WxDxH) Usable interior height Usable interior diameter Weight empty Weight full Maximum capacity Max. vial capacity (2ml)** Max. blood bag capacity (50ml)** litres V3000AB/C 70 939 x 29 x 30 686 736 272 327 6800 852 V3000ABEH/C 89 939 x 29 x 384 889 736 288 36 2000 36 V5000AB/C 93 94 x 372 x 257 737 978 425 499 36400 722 V5000ABEH/C 40 94 x 372 x 384 83 978 452 566 42000 968 ** Capacity is subject to rack type Medical Device Directive PHCbi has become one of the first companies in our industry to introduce Medical Device certification to underline our strong coitment to product design, quality and safety. In 200, PHCbi was awarded certification by TÜVSüd to manufacture blood bank refrigerators, freezers and incubators as Class IIa Medical Devices according to the directives 93/42/EEC and 2007/47/EC. At the same time our quality systems were updated to the latest ISO900 and ISO3485 standards. The use of refrigeration products and cell culture incubators for the preservation and cultivation of cells and tissues for human use in transfusion, regenerative medicine and cell therapy is set to expand. In anticipation of these developing technologies and possible changes in the regulatory landscape, PHCbi began to introduce Medical Device certified products in 20. The first models to be certified include the: MDFDU300H, MDFU55V, MDFDU502VH, MDFDU702VH, MDFU702VX, MDFDC502VX, MDFDC700VX, MDFDU900VPE MDFU542H, MDFU443 MBR305gR, MBR705gR, MBR405gR MCO70AIC, MCO230AIC, MCO70M PHC Corporation, gunma Factory is certified for: Quality management system: ISO900 Medical devices quality management system: ISO3485 023 2

SPECIFICATIONS ULT FREEZERS TwinGuard Upright Freezers TwinGuard Chest Freezers Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Capacity Net weight (approx) Performance Cooling performance 2) Temperature setting range Temperature control range 2) Control Controller Display Temperature sensor Refrigeration Refrigeration system Highstage compressor Highstage refrigerant Lowstage compressor Lowstage refrigerant Insulation material Insulation thickness Construction Exterior material Interior material Outer door lock Inner door/lid Shelves Max. load per shelf Max. load total 3) Vacuum release port Access port position diameter Casters Alarms Power failure High temperature Low temperature Filter Door open Electrical and Noise Level Power Supply Noise Level 4) Options Liquid CO 2 backup Liquid N 2 backup Temperature recorders Circular type Chart paper Ink pen Continuous strip type Chart paper Ink pen Recorder housing Drawers Small inner door kit Small inner door kit Small inner door kit litres 2 boxes º C º C º C W W Ø db(a) set of 2 set of 5 set of 4 MDFDU502VXPE 790 x 882 x 993 630 x 600 x 400 528 384 276 86 50 ~ 90 50 ~ 86 2 x 00 HFC mixed PUF / VIP PLUS 80 2 (insulated) 3 50 45 2 ( automatic, manual) 3 Back x / bottom x 2 7 4 (2 levelling feet) MDF5ID5PW MDF5ID4PW 6) MDFDU702VXPE 030 x 882 x 993 870 x 600 x 400 729 576 320 Microprocessor nonvolatile memory LCD Pt000 Independent DualCooling 55 (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR VBR VBR Filterless design VB 230V 50Hz single phase 52 MDFUB7PW MTRG85CPE RPG85PW 8) PGRPW MTR85HPW RP85PW 8) DF38FPPW MDFS3085PW MDF7ID5PW MDF7ID4PW 7) MDFDC500VXPE 200 x 845 x 070 90 x 640 x 756 575 46 328 MDFDC700VXPE 2300 x 845 x 070 480 x 640 x 756 75 520 358 86 50 ~ 90 50 ~ 86 Microprocessor nonvolatile memory LCD Touch Screen Pt000 Independent DualCooling 2 x 00 HFC mixed PUF / VIP PLUS 70 / 35 Stainless Steel 3 (Styrofoam) Back 7 6 (3 levelling feet) VBR VBR VBR Filterless design VB 230V 50Hz single phase 52 MDFUB5PW MTRG85CPE RPG85PW PGRPW MTR85HPW RP85PW DF38FPPW MDFS3085PW 22 Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Air temperature measured at freezer centre, ambient temperature +30ºC, no load 3) Max. load is the total of the load distributed over all shelves (3) and chamber bottom surface.the weight is the maximum load for chamber inside and excludes load on casters equipped with product. 4) Nominal value. Bacround noise 20dB

Models: MDFDU502VXPE MDFDU702VXPE MDFDC500VXPE MDFDC700VXPE MDFDU502VHPE MDFDU702VHPE MDFDU900VPE MDFC8VPE VIP ECO Upright Freezers VIP Upright Freezers VIP Chest Freezers MDFDU502VHPE MDFDU702VHPE MDFDU900VPE MDFC8VPE 790 x 870 x 990 630 x 600 x 400 528 384 246 030 x 882 x 993 870 x 600 x 400 729 576 278 50 x 870 x 990 00 x 600 x 400 845 672 372 550 x 685 x 945 405 x 490 x 425 84 42 67 86 50 ~ 90 50 ~ 86 86 50 ~ 90 50 ~ 86 80 55~90 60 ~ 80 Microprocessor nonvolatile memory LCD Touch Screen Pt000 Microprocessor nonvolatile memory LCD Touch Screen Pt000 Microprocessor nonvolatile memory LED Pt000 Cascade 750 HC 750 HC PUF / VIP PLUS 80 Cascade 00 HFC 00 HFC PUF / VIP PLUS Autocascade 400 HFC mixed PUF / VIP PLUS 70 45 2 (insulated) 3 50 2 ( automatic, manual) 3 Back x / bottom x 2 7 4 (2 levelling feet) 55 2 (insulated) 3 50 50 2 Back/bottom 7 4 (2 levelling feet) 00 2 Back/bottom 7 4 (2 levelling feet) VBR VBR VBR VB VB VBR VBR VBR VB VB VBR VBR VBR Filterless design 230V 50Hz single phase 52 230V 50Hz single phase 52 230V 50Hz single phase 47 MDFUB7PW MDFUB6PW CVKUB4PW CVKUBN2PW MDF5ID5PW MDF5ID4PW 6) MTRG85CPE RPG85PW 8) PGRPW MTR85HPW RP85PW 8) DF38FPPW MDFS3085PW MDF7ID5PW MDF7ID4PW 7 ) MTRG85CPE RPG85PW PGRPW MTR85HPW RP85PW DF38FPPW MDFS3085PW MDF9IDPW (max 2) 5) MTRG85CPE RPG85PW PGRPW MTR85HPW RP85PW DF38FPPW MDFS3085PW 5) Installation of small inner door kit may affect usable storage capacity. 6) Usable storage capacity will be 320 x 2 boxes with installation of MDF5ID5PW and additional shelf 7) Usable storage capacity will be 480 x 2 boxes with installation of MDF7ID5PW and additional shelf. 8) Requires sensor cover MTRDU700SFPW. 23

SPECIFICATIONS BIOMEDICAL FREEZERS Biomedical ECO 40ºC Plasma Freezer Biomedical 40ºC Plasma Freezer Model Number MDFU542HPE MDFU443PE Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Capacity litres 2 boxes 804 x 772 x 802 658 x 607 x 272 482, 280 FFP packs (300ml) 224 800 x 832 x 80 640 x 65 x 090 426, 300 FFP packs (300ml) 256 Net weight (approx) 34 23 Performance Cooling performance 2) º C 40 2) 40 3) Temperature setting range Temperature control range 2) º C º C 8 ~ 45 20 ~ 40 2) 5 ~ 44 5 ~ 4 3) Control Controller Microprocessor nonvolatile memory Microprocessor nonvolatile memory Display LED LED Temperature sensor Thermistor Thermistor Refrigeration Cooling method Compressor W Direct 400 Cascade + forced air circulation H:400/L:750 Refrigerant HFC HFC Insulation material W PUF PUF Insulation thickness 70 80 Construction Exterior material Interior material Stainless steel Stainless steel Outer door 2 Outer door lock Shelves 4 (fixed) 5 Containers / baskets 4/6/0 Max. load per shelf / container / basket 30 50 Max. load total 00 200 Access port position Back Left diameter Ø 30 40 Interior fluorecent lamp Casters 4 (2 levelling feet) 4 (2 levelling feet) Alarms Power failure VBR (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR High temperature VBR VBR Low temperature VBR VBR Filter VB Door open VB Electrical and Noise Level Power Supply 230V 50Hz single phase 230V 50Hz single phase Noise Level 5) db(a) 42 5 Options Storage systems Temperature recorders Circular type Chart paper Ink pen Recorder housing Continuous strip type Chart paper Ink pen Recorder housing External mounting power failure alarm MTRG85CPE RPG85PW PGRPW MPRS7PW MTR405LHPE RP40PW MPRS30PW MTR405LHPE (40 ~ +4ºC range) or MTR85H (00 ~ +50ºC range) RP40PW 8) or RPG85PW 9) DF38FPPW 9) MPRS30PW 8) Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Air temperature measured at freezer centre, ambient temperature +30ºC, no load 3) Air temperature measured at freezer centre, ambient temperature +35ºC, no load 4) Remote alarm comes with optional power failure alarm MPR48BPW 5) Nominal value Bacround noise 20dB 6) Requires MPR48BPW 7) Defrost method: Cyclical defrost (Ref) / Manual (Frz) 8) For use with MTR405LHPE 9) For use with MTR85HPW 24

Models: MDFU542HPE MDFU443PE MDFU73MPE MDFMU300HPE MDFMU500HPE MPR75FPE Biomedical ECO 30ºC Freezers MPR Pharmaceutical Refrigerators with Freezer MDF73MPE MDFMU300HPE MDFMU500HPE MPR75FPE 770 x 830 x 955 650 x 700 x 520 690 384 52 60 x 598 x 620 490 x 486 x 290 274 50 76 800 x 772 x 802 658 x 607 x 272 482 224 24 900 x 75 x 90 80 x 65 x 894 (Ref), 770 x 552 x 422 (Frz) 45/76 (Ref/Frz) 68 30 2) 8 ~ 35 20~ 30 2) 30 2) 8 ~ 35 20 ~ 30 2) +5 / 30 +2 to +4/ 35 to 5 +2 to +4/ 30 to 20 Microprocessor, nonvolatile memory LED Thermistor Microprocessor, nonvolatile memory LED Thermistor Microprocessor, nonvolatile memory LED Thermistor Direct 400 HFC PUF 60 60 Direct 250 (inverter control) HC 70 Fan forced air circulation (Ref) / Direct cooling (Frz) 7) HFC PUF 40 / 60 4 (fixed) Optional 50 200 Left 30 4 (2 levelling feet) ABS resin 4 (fixed) 4/0/ 30 80 Left 30 4 (2 levelling feet) Styrol resin 2 4 (fixed) 4/6/0 U:30/L:20 00 Back Painted Steel Painted Steel (Ref/Frz) 4, glass window (2), 2 3 (Ref) / 2 (Frz) 25 / 5 (Ref/Frz) 05 2 Back 30 LED 4 VBR VBR VBR VB VBR (Optional) VB(R4) VB(R4) VBR VBR VBR VB 230V 50Hz single phase 42 230V 50Hz single phase 40 230V 50Hz single phase 43 MDFT07SCSW, Set of 2 containers MDFT07STSW, Set of 3 shelves MTRG85CSE RPG85SW PGRSW MPRS7SW MTR405LHPE RP40SW MPRS30SW MPRS470TPW MTRG85CPE RPG85PW PGRPW MTR405LHPE RP40PW MPR48BPW 6) MPRS7PW MPRS30PW MTRG3504CPE RPG3504PW PGRBPW MTR062LHPE (Ref) / MTR405LHPE (Frz) RP06PW (Ref) / RP40PW (Frz) MPRS30PW 25

SPECIFICATIONS MPR PHARMACEUTICAL REFRIgERATORS Models: MPR72(R)PE I MPR4(R)PE MPR54(R)PE I MPR04(R)PE MPR Pharmaceutical Refrigerators Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Net weight (approx) Capacity Performance Temperature setting range Control Controller Display Temperature recorder Temperature sensor Refrigeration Cooling method Defrost method Refrigerant Insulation Construction Exterior material Interior material Outer doors Outer door lock Inner door Shelves Drawers Max. load per shelf/drawer Max. load total Access port position diameter Casters Interior light Alarms Power failure High temperature Low temperature Door open Electrical and Noise Level Power Supply Noise Level 2 Options Temperature recorders Temperature chart recorder chart paper recorder housing Circular type chart paper Ink pen recorder housing External mounting power failure alarm litres º C Ø db(a) MPR72PE MPR72RPE 770 x 830 x 955 650 x 70 x 500 684 67 74 93 2 ~ 23 Microprocessor LED Thermistor Forced cool air circulation Forced type (cycle defrost), fully automatic HFC PUF door, double pane glass, self closing 4 wire shelves, polyethylenecoated 5 coated steel drawers 50 40 200 200 3 Left/right/top 30 4 Fluorescent (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR (Optional) VBR VBR VB 230V 50Hz single phase 4 MTR062LHPE RP06PW MPRS30PW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) MPR4PE MPR4RPE 440 x 830 x 950 320 x 70 x 500 364 359 248 287 2 ~ 23 Microprocessor LED Thermistor Forced cool air circulation Forced type (cycle defrost), fully automatic HFC PUF 2 doors, double pane glass, self closing 8 wire shelves, polyethylenecoated 0 coated steel drawers 40 320 3 Left/right/top 30 4 Fluorescent VBR (Optional) VBR VBR VB 230V 50Hz single phase 42 MTR062LHPE RP06PW MPRS30PW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) 40 400 Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Nominal value Bacround noise 20dB 3) Remote alarm comes with optional power failure alarm MPR48BPW 26

SPECIFICATIONS INCUSAFE CO 2 & MULTIgAS INCUBATORS Models: MCO70MPE series Multigas incubators IncuSafe Multigas Incubators Model Number External Dimensions (W x D x H ) Internal Dimensions (W x D x H) Volume liters Net Weight Performance Temperature Control Range & Fluctuation ºC Temperature Uniformity 2 ) ºC CO 2 Control Range & Fluctuation 3 ) % O 2 control range & Fluctuation 4) % Humidity Level & Fluctuation %RH Control Temperature Sensor CO 2 Sensor O 2 Sensor Display Construction Exterior Material Interior Material Insulation Material Heating Method Outer Door Outer Door Lock Field Reversible Door Inner Doors Shelves Shelf Dimensions (W x D x H) Max. Load per Shelf Max. Shelf Capacity Access Port Access Port Position Access Port Diameter Ø Alarms Power Failure Out of Temperature Setting High Temperature Out of CO 2 Setting Out of O 2 setting Door open Electrical and Noise Level Power Supply V Frequency Hz Noise Level 5) db Options SafeCell UV System H 2 O 2 Decontamination Board Electric Door Lock with Password H 2 O 2 Vapour Generator H 2 O 2 Reagent, pack of 6 bottles Multiple Inner Doors CO 2 Gas Pressure Regulator N 2 Gas Pressure Regulator Automatic CO 2 Cylinder Changeover System Semiautomatic one point Gas Calibration Kit InCu safe Shelf InCu safe Half Tray System Double Stacking Bracket* Stacking Plate* Roller Base Optional counication systems 7) Analogue interface (420mA) MCO70MPE MCO70MUVPE MCO70MUVHPE 620 x 70 x 905 490 x 523 x 665 6 79 AT +5 ~ +50, ±0. ±0.25 0 ~ 20, ±0.5 8 and 22 80, ±0.2 95, ±5 Thermistor Dual IR Stabilized Zirconia Sensor LCD Touch Screen Painted Steel (rear cover not painted) Stainless Steel CopperEnriched Alloy Extruded polystyrene Direct Heat & Air Jacket System Optional Optional Standard Standard 4 gastight made of tempered glass 3 x Stainless Steel Copperenriched Alloy 470 x 450 x 2 7 0 Rear Upper Left 30 (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) R VBR VBR VBR VBR VB 230 50 25 MCO70UVSPE 6) Standard Standard MCO70HBPE 6) MCO70HBPE 6) Standard MCO70ELPW 6) MCO70ELPW 6) Standard MCOHPPW 6) MCOH2O2PE Standard MCO00LPW MCO00LPW MCO2GCPW MCOSGPW MCO70STPW MCO25STPW MCO70PSPW MCO70SBPW MCO70RBPW MCO420MAPW Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections 2,3 & 4) Ambient temperature 23ºC, setting 37ºC, CO 2 5%, O 2 5%, no load 5) Nominal value Bacround noise 20dB 6) Requires MCO70HBPE, MCO70ELPW, MCOHPPW and SafeCell UV option for H 2 O 2 decontamination 7) Can only be fitted with one counications interface. 27

SPECIFICATIONS INCUSAFE CO 2 & MULTIgAS INCUBATORS IncuSafe CO 2 Incubators Model Number External Dimensions (W x D x H ) Internal Dimensions (W x D x H) Volume liters Net Weight Performance Temperature Control Range & Fluctuation ºC Temperature Uniformity 2 ) ºC CO 2 Control Range & Fluctuation 3 ) % Humidity Level & Fluctuation %RH Control Temperature Sensor CO 2 Sensor Display Construction Exterior Material Interior Material Insulation Material Heating Method Outer Door Outer Door Lock Field Reversible Door Inner Doors Shelves Shelf Dimensions (W x D x H) Max. Load per Shelf Max. Shelf Capacity Access Port Access Port Position Access Port Diameter Ø Alarms Power Failure Out of Temperature Setting High Temperature Out of CO 2 Setting Water level Door open Electrical and Noise Level Power Supply V Frequency Hz Noise Level 5) db Options SafeCell UV System H 2 O 2 Decontamination Board Electric Door Lock with Password H 2 O 2 Vapour Generator H 2 O 2 Reagent, pack of 6 bottles Multiple Inner Doors CO 2 Gas Pressure Regulator N 2 Gas Pressure Regulator Automatic CO 2 Cylinder Changeover System Semiautomatic one point Gas Calibration Kit InCu safe Shelf InCu safe Half Tray System Double Stacking Bracket* Stacking Plate* Roller Base Roller bottle rack mounting kit Automatic water supply system kit Optional counication systems 7) Analogue interface (420mA) MCO70AICPE MCO70AICUVPE MCO70AICUVHPE 620 x 730 x 900 490 x 523 x 665 65 80 AT +5 ~ +50, ±0. ±0.25 0 ~ 20, ±0.5 95, ±5 Thermistor Dual IR LCD Touch Screen Painted Steel (rear cover not painted) Stainless Steel CopperEnriched Alloy Extruded polystyrene Direct Heat & Air Jacket System Optional Optional Standard Standard gastight made of tempered glass 4 x Stainless Steel Copperenriched Alloy 470 x 450 x 2 7 0 Rear Upper Left 30 (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) R VBR VBR VBR VB 230 50 29 MCO70UVSPE 6) Standard Standard MCO70HBPE 6) MCO70HBPE 6) Standard MCO70ELPW 6) MCO70ELPW 6) Standard MCOHPPW 6) MCOH2O2PE MCO70IDPW MCO00LPW MCO2GCPW MCOSGPW MCO70STPW MCO25STPW MCO70PSPW MCO70SBPW MCO70RBPW MCO420MAPW 28 * If stacking two incubators, make sure the doublestacking dedicated securing hardware and spacer are used. (see options)

Models: MCO70AICPE series MCO230AICPE series MCO80ICPE IncuSafe CO 2 Incubators MCO230AICPE MCO230AICUVPE MCO230AICUVHPE 770 x 730 x 905 643 x 523 x 700 230 90 IncuSafe Reach In CO 2 Incubator MCO80ICPE 986 x 853 x 2040 806 x 693 x 524 85 275 AT +5 ~ +50, ±0. ±0.25 0 ~ 20, ±0.5 95, ±5 AT +5 to 50 (AT; 20 to 35) ±0.5 0 ~ 20, ±0.5 Normal mode; >80% R.H., High mode; > 90% R.H. Thermistor Dual IR LCD touch screen Thermistor IR LED Painted Steel (rear cover not painted) Stainless Steel CopperEnriched Alloy Extruded polystyrene Direct Heat & Air Jacket System Optional Optional Standard Standard gastight made of tempered glass 4 x Stainless Steel Copperenriched Alloy 620 x 450 x 2 7 0 Rear Upper Left 30 SS copper alloyed PUF N (laminar airflow) double paned glass N Option 5 30 50 5 2 Left and right hand side 40 R VBR VBR VBR VB R VBR VBR VBR V V 230 50 25 230 50 33 MCO70UVSPE 6) Standard Standard MCO70HBPE 6) MCO70HBPE 6) Standard MCO70ELPW 6) MCO70ELPW 6) Standard MCOHPPW 6) MCOH2O2PE MCO00LPW MCO2GCPW MCOSGPW MCO230STPW MCO35STPW MCO70PSPW MCO230SBPW MCO230RBPW MCO80UVSPE MCO80IDPW (5 small doors) MCO00LPW MCO80GCPW MCO80STPW MCO80RBSPW MCO80ASPW MCO420MAPW MCO420MAPW ) Exterior dimensions of main cabinet only, excluding handle and other external projections 2,3 & 4) Ambient temperature 23ºC, setting 37ºC, CO 2 5%, O 2 5%, no load 5) Nominal value 6) Requires MCO70HBPE, MCO70ELPW, MCOHPPW and SafeCell UV option for H 2 O 2 decontamination 7) Can only be fitted with one counications interface. 29

SPECIFICATIONS MIR HEATED INCUBATORS Models: MIRH63PE I MIRH263PE Model Number External Dimensions (W x D x H ) Internal Dimensions (W x D x H) Volume Net Weight Performance Temperature control range Fluctuation Temperature uniformity Control Temperature sensor Display Construction Exterior material Interior material Insulation material Outer door Inner door Shelves Max. load per shelf Max. total load Alarms Out of temperature setting High temperature Electrical and Noise Level Power Supply Frequency liters V Hz MIR Heated Incubators MIRH63PE MIRH263PE 580 x 595 x 820 730 x 645 x 870 450 x 460 x 450 600 x 50 x 500 93 53 50 67 Ambient temp +5 ~ +80 ±0.2 (<60) ~ ± 0.5 (60 ~ 80) ± Thermistor LED SS SUS304 Glass fibre 2 3 5 5 30 30 (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VB VB 230 50 Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details Appearance and specifications are subject to change without notice. 30

SPECIFICATIONS MIR COOLED INCUBATORS Models: MIR54PE I MIR254PE I MIR554PE MIR Cooled Incubators Model Number External Dimensions (W x D x H ) Internal Dimensions (W x D x H) Volume liters Net Weight Performance Temp control range and fluctuation ºC Temperature uniformity ºC Performance ambient temperature ºC Control Temperature Sensor Refrigeration Insulation material Insulation thickness Compressor Refrigerant Cooling method Construction Exterior material Interior material Outer door Outer door lock Reversible door Inner door Shelves Max. load per shelf Max. total load Access port position diameter Ø Interior fluorescent lamp Alarms Power failure High temperature Low temperature Door open Electrical and noise level Power supply Frequency Noise level 3) Options Stacking kit Door padlock bracket Additional illumination kit Inner doors Door window blanking plate MIR54PE MIR254PE MIR554PE 700 x 580 x 08 620 x 368 x 555 23 78 700 x 580 x 68 620 x 368 x 088 238 08 800 x 832 x 80 640 x 550 x 60 406 95 0 ~ +60 (AT; +5 ~ +35, no load), ±0.2 with Heater PID control (SV 50), ±.5 with Compressor control (SV 5) PID control: 7ºC above AT for MIR54/254; 0ºC above AT for MIR554 ±0.5 SV (35) 20, no load Thermistor PUF 40 50 R34a N 40 250 R404A Forced air circulation SS SUS304 MIRLP option N 80 250 R404A N 2 small inner doors (MIR55ID option) MIRLP option 3 20 6 left side 5 20 00 left side 40, 5, with MIRL5PE 2) option 5 50 250 2 left and right side 4 MIRS54SBPW MIRLPPW MIRL5PE MIR54BPPW (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR VBR VB 230 50 44 MIRLPPW MIRL5PE MIR254BPPW R 45 MIRL5PE MIR55IDPW Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) MIRL5PE operates between +2 C and +50 C 3) Nominal value. Bacround noise 20dB Appearance and specifications are subject to change without notice. 3

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