Department Name Address Tel / Fax Date of Issue Life Sciences Institute 28 Medical Drive EMERGENCY RESPONSE PLAN FOR Centre for Life Sciences Prepared By Name Zornosa Arnel Blastique Appointment Assistant Manager Last Date of Review September 2010
TABLE OF RECORDS EMERGENCY PLAN REVISION S/N PLAN VERSION DATE OF APPROVAL NAME OF APPROVING OFFICER SIGNATURE OF APPROVING OFFICER * Date of Exercise - Date where the newly drafted /revised emergency plan has been validated. Emergency plan should only be endorsed and approved after it has been exercised and validated by OSHE EMERGENCY EXERCISE CONDUCTED S/N DATE OF EXERCISE NAME OF CONDUCTING OFFICER SIGNATURE OF CONDUCTING OFFICER 1 06 September 2010 Fire Drill Arnel Zornosa 2 Table Top Exercise Sini Mathew
1 SITUATION 1.1 Introduction The Centre for Life Sciences (CeLS) is the first research facility in NUS to be fully dedicated to conducting research in Life Sciences. This Life Sciences complex houses 2 for Life Sciences Institute research programmes: Immunology and Neurobiology. Other independent research institutions are also housed in this facility; Cancer Science Institute of Singapore, Clinical Imaging Research Centre, Institutional Animal Care and Use Committee and SMART Infectious Diseases. This five-storey building has a floor area of 20,000 square meters and has about 450 scientists, researchers and graduate students. There are also Core and Animal Facilities in this Centre. Various local companies are supplying flammable chemicals to the Centre as follows: The Centre is under the jurisdiction of: Director: Prof Peter Little Life Sciences Institute National University of Singapore Tel: (65) 65168061 Fax (65) 68270830 E-mail peterlittle@nus.edu.sg 1.2 Area of Operations 1.2.1 Location of Installation and its main access road The Centre for Life Sciences building facility is located at 28 Medical Drive, Singapore 117456 as the building is located on a hilltop, there is only one vehicular access in and out of the facility premises. The only vehicular access is through Medical drive from Lower Kent Ridge Road or the emergency entrance of the National University Hospital.( Please refer to Annex A for CeLS Location) 1.2.2 General Description of Site It is bounded on the northeast by MD 2, a 4-storey University animal facility building. The building is not currently operational yet. On the east is the National University Hospital, south and west by Prince George Park. The south and west boundaries are vertical cut-off from the hillside where CeLS is built. There are no vehicular nor pedestrian access except for part of the south boundary where a link way is commonly utilized by students as access from nearby hostels. 1.2.3 Layout of Installation Please refer to attached floor plans for layout information of the facilities at CeLS. To provide a brief description of the internal building layout plan with the aid of a schematic diagram.
1.2.4 Location, storage and quantities of hazardous products, chemicals and gases (See Annex B for Inventory List of Hazardous Substances) Detailed description of the location, quantity stored and the storage conditions of hazardous material such as storage temperature, pressure etc. Location of the hazardous material must be indicated on the site plan clearly. (See Annex C for Location of the Hazardous Substances) 2 AIM The aim of this emergency response plan is to detail the various operational actions that need to be undertaken to respond in case of emergency situations such as fire, chemical leaks/spillages, biological emergencies etc within the facility to prevent and reduce injury to personnel and minimize property damage and loss.
3 EMERGENCY RESPONSE 3.1 FIRE Raise the alarm by activating the nearest fire alarm break glass call point. Attempt to extinguish any incipient fire without taking personal risk (refer to Appendix A) provided subject has been trained in the proper use of a fire extinguisher and is confident in his/her ability to cope with the hazards of fighting a fire. There are several different fire extinguishers available in every area of a building on campus. Occupants are expected to know the location of the fire equipment by referring to the evacuation floor plan found on every floor. The acronym PASS can be used to operate a fire extinguisher as follows: P A S S Pull the pin to allow user to squeeze the lever in order to discharge the extinguisher Aim the hose at the base of the fire. Stand a safe distance away from the fire. Squeeze the handle fully to discharge the fire extinguisher agent Sweep the hose from side to side Notify Campus Security (Tel No: 6874 1616) and Singapore Civil Defence Force (Tel No: 995) of the activation of fire alarm and state the following: i) Location of the fire ii) Nature of fire, if known iii) Injury to personnel, if known iv) Informant s particulars and contact number The caller shall not replace the telephone set until the address has been repeated by the operator at the SCDF Control Room. Stop all work, shut down electrical equipment / heating appliances/ machinery Alert people that there is a fire in the building Rescue any person in immediate danger to safety as long as it is safe to do so If clothing of person is on fire, adopt the stop, drop & roll method or drench with water using the water shower if available Close all doors to rooms, escape staircase and corridors to contain the smoke and/or fire. Proceed to nearest exit and evacuate safely Do not use lifts in case of fire Proceed to the designated Assembly Point Do not re-enter building until it is safe to do so
3.2 CHEMICAL SPILL Minor spills in the labs: Notify lab supervisor and report the location of the spill and type of chemical involved Follow lab procedures for eyewash rinse or shower Evacuate persons in the immediate area if necessary Clean the spill ONLY by those with suitable training and equipment (MSDS sheets and spill kits are available in each lab, use these documents for information and correct procedure) Wear personal protective equipment (goggles, gloves, respirators, shoe covers) When toxic chemicals come into contact with skin, remove any clothing and immediately flush the affected area with clear water for at least 15 minutes in the nearest Emergency Eyewash station location. (see Appendix C for location of Emergency Eyewash station) If a chemical splashes in the eye, immediately flush it with clear water for 15 minutes in the nearest eye wash fountain Use the appropriate kit to neutralize and absorb chemical spill Collect waste & seal in proper container and label it clearly Major spills in the labs: Notify Campus Security (Tel No: 6874 1616), Singapore Civil Defence Force (Tel No: 995) & lab supervisor of the chemical spill and state the following: i) Location of the incident ii) Nature of material spilled, if known iii) Injury to personnel, if known iv) Informant s particulars and contact number Assist any injured persons. Isolate contaminated persons Avoid contamination or chemical exposure Close doors or control access to spill site Communicate critical spill information to first responders Follow evacuation instructions External hazardous material release (Toxic Cloud): Listen for instructions on public address system if available Ensure windows and doors remain closed Inform occupants to stay indoors until hazard is declared over Ensure maintenance of the safety and comfort of occupants Prior to responding to any chemical spills, lab users should be familiar with the hazards involved. DO NOT attempt to handle a spill without understanding the risk involved. If lab users are unfamiliar with handling chemical spillage:
Leave the area and DO NOT attempt to clean up the spillage Warn others of the spill Notify lab supervisor & Campus Security Wait for further assistance.
3.3 BIOHAZARD MATERIAL SPILL Decontamination and Clean-up procedures Notify lab supervisor and report the location of the spill and material involved For spill outside biosafety cabinet, evacuate area and allow potential aerosols to settle for at least 10 minutes. Post signage indicating spill cleanup in progress, if necessary. For spill inside Biosafety cabinet, leave the cabinet TURNED ON Put on the proper Personal Protective Equipment (such as long-sleeved gowns, safety glasses or goggles, rubber gloves, and respirator, as necessary) Use the appropriate decontamination solution to treat the spill area. Pour it gently, directing its flow into the spill area, so that the area of spill in not increased. Cover the area with absorbent and allow sufficient contact time to absorb the spill (see decontamination solution recommendations for contact time) Transfer all materials from the spill area into an autoclavable pan and autoclave all the clean-up materials. Alternatively, place in an appropriate biohazard waste container for collection by a contract waste collector. Wash and mop the spill area with decontamination solution for a second time Remove gown, rubber gloves, safety glasses or goggles, and respirator (if necessary) and be sure to use appropriate decontamination solution prior to autoclaving for disposal or before disposal in the biohazard waste container Wash hands thoroughly after the clean-up procedures Prior to responding to any biohazard spillage, lab users must thoroughly understand the hazards involved. DO NOT handle any spillage without understanding the risk involved, without the appropriate personal protective equipment, or if you simply do not feel comfortable doing so. If lab users are unfamiliar with handling biohazard spillage: Leave the area and DO NOT attempt to clean up the spillage Warn others of the spill Notify lab supervisor & Campus Security Wait for further assistance.
3.4 GAS LEAKAGE Inert or non-hazardous gas leakage Open all windows and doors to ventilate the area Use a gas leak detector or soapy water or other suitable solution to detect location of leakage Secure leakage by tightening, reconditioning or replacing the valve, regulators or tubing connections to equipment If leak persists, move cylinder to a ventilated area, report to lab supervisor and consult supplier for more instructions Cryogenic gas leak Open all windows and doors to ventilate the area Shut off source of leakage if it s safe to do so If leak persists, evacuate everyone out of the laboratory to avoid asphyxiation Notify Campus Security (Tel: 68741616) & lab supervisor and report the location of the leakage and type of gas involved. Consult supplier for instructions Toxic Chemical / Flammable gas leak Open all windows and doors to ventilate area Shut off source of leakage if it s safe to do so If leak persists, evacuate everyone out of the laboratory and raise the building fire alarm by activating the nearest fire alarm break glass call point. Notify CeLS Security Officer (X64043) Campus Security (Tel: 68741616), Singapore Civil Defence Force (Tel No: 995) & lab supervisor and report the location of the leakage and type of gas involved. Do not light any heat or electrical sources If the leak resulted to a fire, please follow the fire emergency response in section 3.1.
3.5 RADIATION LEAK Immediately notify lab supervisor & Campus Security (Tel: 68741616) of the incident and report the location of the incident. Warn others within the vicinity of the incident. Regulate entry to the scene of the incident If evacuation is necessary, switch off apparatus producing ionizing radiation Protective apron should be donned when switching off apparatus Safety officers to identify and immediately isolate all persons who might have received high exposures from the radiation All necessary medical surveillance & personnel monitoring should be provided. Exposures of persons involved should be recorded All working areas exposed to the radiation should be thoroughly monitored before work is allowed to recommence. All affected equipment should be checked and cleared safe to be used Contact OSHE at 65161084 to coordinate waste pick-up 4 COORDINATING INSTRUCTIONS Key Personnel Emergency Contact Numbers The key personnel to be notified must be contactable during office hour and after office hour (Contact No. must include either home, mobile contact number) (See Annex D for Key Personnel Emergency Contact Numbers) 5 SAFETY & EMERGENCY RESPONSE EQUIPMENT All lab users should know the procedures for responding to emergencies in their respective work area. The emergency response plan should be periodically reviewed and always be familiar of the locations of the safety & emergency equipment in the labs such as: First aid kits Eyewash fountains and emergency showers Spill kits Fire extinguishers & hosereels Emergency exits and evacuation routes (See Annex C for Location of Safety & Emergency Equipment)
LOCATION PLAN Annex A
INVENTORY LIST OF HAZARDOUS SUBSTANCES Annex B
Annex C LOCATION OF THE HAZARDOUS SUBSTANCES Ethidium Bromide 200 ml Kanamyuin 50 mg Sodium Selenite 10 mg Zinc Chloride 100 g 5 th Storey Propanol 15.0 L Ethanol 20.0 L Methanol 30.0 L Acetone 30.0 L Acetonitrite 10.0 L Xylene 5.0 L Butanol 5.0 L Mercaptoethanol 200 ml Yeast Extract 2 kg Glucose 5 kg Magnesium Chloride 2 kg Fructose 1 kg Silver Nitrate 1 kg Histoclear 5 L DMSO 500 ml Aleopene 25 g
Annex C Aspatic Acid 100 g Atropine 100 g Silver nitrate 500 g Sodium Azide 100 g Kananyacin 1 g Boric Acid 1 kg Ethidium Bromide 100 ml Ethanol Methanol Acetone Propanol Isoanyl Alcohol Chloroform Toluene IsoOctane Xylene Mecapto Ethanol 100 ml Tryptone 1 kg Yeast Extract 500 g Agar 10 kg Calcium Chloride 2 kg Maltose 5 kg Manganese Chloride 2 kg 4 th Storey
Annex C Dodacyl Sulfate 2.0 kg Dichloromethane 5.0 L Pyridine 2.0 L Histoclear 5.0 L DPX Mount 5.0 L Agar 5.0 kg Maltose 2.0 kg Glucose 5.0 kg DPX Mount 5.0 L Agar 5.0 kg Maltose 2.0 kg Glucose 5.0 kg Eosin Solution 2.0 L May Greenwald Stain 1.0 kg Ethidium Bromide 100 ml 3 rd Storey
Annex C Ethanol 10 L Methanol 15 L Hydrogen Peroxide 1 L Acetone 10 L Chloroform 2 L 2 nd Storey Triton X 100 1.0 L Formalin 45 L HPLC Buffer 20 L Eosin 2.0 L Sodium Selenite 100 g Zinc Chloride 100 g Arsenic Oxide 100 g Ethidium Bromide 200 ml
Annex D Key Emergency Contact Numbers S/N NAME CONTACT NUMBER 1 Director s Office <Peter Little> <Life Sciences Institute / 5 th Storey> 2 Building Manager <Arnel Zornosa> <Life Sciences Institute / 5 th Storey> 3 Laboratory Manager <Rasvinder Kaur> <SMART, Infectious Diseases / 5 th Storey> 65167544 65167527 65161987 4 Laboratory Manager 65167626 <Chua Chian Ling Clement> <Neurobiology & Aging / 4 th Storey> 5 Laboratory Manager 65165019 <Man Wai Jin> <Immunology Programme / 3 rd Storey> 6 Laboratory Manager 65162461 <Lai Yih Shin> <CSI Singapore / 3 rd Storey> 7 Laboratory Manager 65167280 < Benjamin Lawrence George > < CSI Singapore/ 2 nd Storey> 8 Faculty Safety Officer 65166184 Dr. Sini Matthew 9 Office of Safety, Health & Environment 65161084 10 Campus Security 68741616 11 University Health Centre 6776 1631 / 6516 2880 12 National University Hospital 6779 5555 13 Fire/Ambulance 995 14 Police 999