PATHOLOGY, BLOOD AND TRANSPLANT SCIENCES

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PATHOLOG, BLOOD AND TRANSPLANT SCIENCES Model Ranges: MBR Blood Bank Refrigerators MPR Pharmaceutical Refrigerators Biomedical &Plasma Freezers VIP Series ULT Freezers Cryogenic Freezers MIR Cooled Incubators IncuSafe Cell Culture Incubators PHCbi products provide the ideal environments for the storage of blood and blood products, cells and tissues for transplant sciences and in the research and support of new generation therapies and treatments. www.phchd.com/eu/biomedical

PHCbi Solutions offer: Precise uniformity Temperature stability Microprocessor based controller Quiet, reliable compressors Sample safety Energy savings Alarms & Monitoring CFCFree Ergonomic design Service and support 2

Innovative solutions for Pathology, Blood and Transplant Sciences Table of Contents MBR Blood Bank Refrigerators Dedicated storage for biomedical samples 6 8 Find the right laboratory equipment for your needs 4 MBR Blood Bank Refrigerators 6 MPR Pharmaceutical Refrigerators 8 Biomedical & Plasma Freezers (ºC / 40ºC) TwinGuard & VIP ECO freezers (86ºC) 4 Cryogenic Freezers (50ºC) 8 CBS Isothermal Freezers (90ºC) 9 MIR Cooled Incubators 20 IncuSafe CO 2 Incubators 2 Validation 24 3

Find the right laboratory Blood Bank Refrigerators 4ºC Refrigerators Robust design for safest storage of whole blood Plasma & Biomedical Freezers ºC / 40ºC Freezers The ideal freezing environment for the preservation of fresh frozen plasma TwinGuard Freezers 86ºC Ultralow Freezers The safest ultralow temperature freezers for the storage of high value samples 4 Liquidloaded monitor bottles designed to mimic the shape and thermal properties of blood bags. Stable temperature control. Designed to minimise coldair loss, even with frequent door openings. Certified as a Class IIa Medical Device. Low running costs. More efficient cooling due to a high latent heat of evaporation. Direct cooling system for uniform temperature control. Fullheight storage containers on each shelf. Double outer doors. Low environmental impact. Dual Cooling refrigeration system for ultimate sample protection. Intelligent 'ECO mode' operation results in lower running costs. Vacuum release port for improved accessibility. VIP PLUS insulation: technology that maximises storage capacity. Quiet operation. Userfriendly filterless design.

equipment for your needs Cryogenic Freezers 50ºC Cryogenic Freezers Cooled Incubators Wide temperature range CO 2 Incubators Incubators from 49 litres to 85 litres The most uniform storage temperatures for cryopreservation solutions Allround performance Optimising cell culture outcomes and reproducibility No cross contamination. Safe and convenient usability. Specially designed cascade refrigeration system. Standard LN 2 backup. Low operational costs. Convenient control with LCD panel. Saves costs on LN 2. Prevention of media drying because of unique fan positioning. Prograable operation. Wide temperature range from 0ºC to +60ºC with excellent uniformity. Precise temperature control for accurate, repeatable conditions. Comprehensive alarm system. Glass door. Integrated shelfsupports. Fullcolour LCD touch screen. USB port. Excellent control of CO 2 and temperature. Dew stick prevents condensation. Removable, easytoclean, humidifying pan. Certified as a Class IIa Medical Device. 5

MBR Blood Bank Refrigerators MBR Blood Bank Refrigerators provide the ideal +4ºC environment for safe and reliable storage of whole blood. These are designed to create stable, reliable temperature control preset to 4ºC with precise toptobottom temperature uniformity. The refrigerators feature a highly efficient refrigeration system that provides superior temperature recovery, rapid cooling, and quiet performance. STABLE TEMPERATURE CONTROL Temperature is controlled by two sensors located in the liquidloaded monitor bottles, which are in the shape of a blood bag. Two thermistor sensors for constantly monitoring the temperature in both the upper and lower part of the chamber. Microprocessor control ensures the most accurate temperature control available. Multi airflow plenum system ensures excellent temperature uniformity in larger capacity models. (MBR704GR, MBR405GR). Temperaturemaintained defrost, designed with thermal sensors and heaters on the evaporator. MEDICAL DEVICE DIRECTIVE 6 Model: MBR5GRPE PHCbi's MBR5GRPE and MBR705GRPE Blood Bank Refrigerators are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes.

Models: MBR5GRPE I MBR705GRPE I MBR405GRPE TEMPERATURE VARIATIONS PREVENTED MBR series are designed to minimize cold air loss even with frequent door openings. Seperated transparant inner doors minimize the chamber air leakage during door openings. Foamedinplace insulation in the walls and magnetic sealed outer doors with doublepane glass window prevent chamber air leakage. Large air circulation fan enables rapid temperature recovery after door openings. USER FRIENDL DESIGN Selectable storage system to suit user needs. Fluorescent interior lamp with ON/OFF switch and a large view window in the outer door provide a clear view of stored items. Digital display is easy to see, and can be calibrated through the control panel. ALARM AND SAFET FUNCTIONS To ensure the safety of critical blood supplies MBR series provide the following safety functions. Audible and flashing LED visual alarms with remote alarm contacts, in the event of power failure, high or low temperature condition, or due to thermal sensor abnormality. Door alarm and key lock are standard features. Reactivating buzzer, lamp and remote alarm contact. (min. after buzzer stops). Builtin temperature recorder. Audible and flashing LED Visual alarms Audible and flashing LED visual alarms with remote alarm sounds, in case of power failure, high or low temperature condition, or during any thermal sensor abnormality. Stable Temperature Control Two thermistor sensors constantly monitor the temperature in both the upper and lower part of the chamber. The sensors are located in the liquid loaded monitor bottles, which are in the shape of a blood bag to accurately simulate product temperature. Insulated windows Insulated window prevents condensation and ensures temperature uniformity. Interior Lamps Fluorescent interior lamp with ON/OFF switch and a large view window in the outer door provide a clear view of stored items. Model: MBR405GRPE 7

MPR Pharmaceutical Refrigerators In the Biomedical field they provide effective storage of critical and high value supplies, samples, reagents and test kits. ADJUSTABLE SHELVES (MPR72/4) The shelves can be arranged to accoodate all types of samples. The R models are fitted with pullout drawers. With a profile of 00 and 5 front to back, these drawers are deep enough to hold large bottles or reagent kits. POWERFUL REFRIGERATION To cope with frequent door openings, Pharmaceutical refrigerators are equipped with powerful, hermetically sealed compressors. Model: MPR72PE STANDARD ALARM & SAFET FEATURES Pharmaceutical refrigerators are fitted with buzzers and flashing lights to warn of high and low temperature problems. In the event of an irregular rise in cabinet temperature, the heater automatically shuts off and forced air circulation brings the temperature down. TEMPERATURE STABILIT PHCbi s temperature control system with thermistor monitor and microprocessor control reliably maintains cabinet temperature at the set level and is unaffected by ambient temperature. Forced air circulation ensures that the cabinet temperature returns to the set point quickly after door openings. 8

Models: MPR72PE I MPR72RPE I MPR4PE I MPR4RPE Dedicated storage for biomedical samples HFC REFRIGERANT & CFC FREE INSULATION PHCbi biomedical equipment is designed for low environmental impact. The MPR72 and 4 series use HFC refrigerant, and the foamedinplace insulation is also CFC free. LARGE FANS The 20 diameter fan ensures an even temperature throughout the cabinet (MPR4/R models have a double flow system with two fans). Heat spots from powered test apparatus are minimized and pulldown characteristics after door openings are outstanding. Model: MPR4PE Adjustable shelves (MPR72/4) The height adjustable shelves can be arranged to accoodate a variety of sample types and specimen racks. 2 Drawer type (MPR72R/4R) The R models are fitted with pullout drawers. With a profile of 00 and 5 front to back, these drawers are deep enough to hold large bottles or reagent kits. They also allow Model: MPR4RPE convenient, spaceefficient storage and management of patient medications and other items. 2 2 9

Models: MPR54PE I MPR54RPE I MPR04PE I MPR04RPE MICROPROCESSOR CONTROLLED An electronic sensor accurately monitors chamber temperature and feeds the information to the microprocessor for precise control at preset temperature. Fans ensure gentle air circulation to provide uniform top to bottom temperature control after frequent door openings. PHCbi s easily calibrated, reliable and stable controls make validation easier. ERGONOMIC DESIGN The ergonomic design of the MPR series pharmaceutical refrigerators provides a clear view of stored items through the large framed windows. The slim profile allows for easyreach retrieval of your products. Users can choose from two types to suit their needs; one with all wire shelves or one with sliding racks on one side. Safe and reliable sample storage Visual LED Alarm Alerts Audible and flashing LED visual alarms alert you to the unlikely event of either a high or low temperature condition. An overshooting prevention circuit automatically switches off the fan motor or heater, if the inside temperature rises abnormally. Easy to read digital display Temperature readings are displayed in gradients of ºC for configurable temperatures ranging from 2º to 4ºC. Cabinet Construction: View window door design with protective film for safety. Key locked doors. Black out glass design is optional. Plenums Direct Airflow: PHCbi s plenum design features uniform cold air flow distribution throughout the chamber to ensure temperature uniformity essential for validated storage requirements. Model: MPR54RPE 0

Models: MDFU542HPE Biomedical ECO 40ºC Plasma Freezer The MDFU542HPE provides an ideal freezing environment for the preservation of blood plasma, vaccines, test samples, and other biological specimens. The Biomedical Eco Series freezers with natural refrigerants minimise energy consumption, reduce environmental impact and save money while providing superior stability and uniformity. A comprehensive alarm system and Class IIa Medical Device Certification ensure this freezer provides unsurpassed reliability and sample security. 023 The MDFU542HPE is certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of storing cells, DNA and/or frozen plasma (For EU countries only) LARGE STORAGE CAPACIT 0ml Fresh frozen plasma bag x 280 pieces. RELIABLE SAMPLE SECURIT A comprehensive visual and audible alarm system with remote alarm contacts ensures users are aware of any abnormalities and can take appropriate actions. Selfdiagnostic system. Standard door lock allows a padlock to be fitted for extra security. An access port allows external temperature monitoring with the use of a probe, or an optional temperature chart recorder can be added. STABLE & UNIFORM TEMPERATURE DESIGN Double outer doors. Fullheight storage containers on each shelf. Cooling tubes under every shelf. Direct cooling system for uniform temperature control. Manual defrost ensures a stable environment with no large temperature. NATURAL HDROCARBON (HC) REFRIGERANTS More efficient cooling due to a high latent heat of evaporation. Greater energy efficiency. Up to 28% reduction in power consumption and running costs. Exceptionally low global warming potential. Better for the environment. Model: MDFU542HPE USER FRIENDL DESIGN Builtin door latch for each door. Easy calibration through the control panel.

Biomedical ºC / 40ºC Freezers STABLE TEMPERATURE CONTROL The MDFU73M provides precise and uniform storage temperatures regardless of ambient conditions through microprocessor temperature control. ENERGSAVING OPERATION The specially designed compressor results in an energysaving medical freezer with superior cooling and quiet operation. Sample storage Microprocessor controls: Configure temperature setpoints, alarms, monitoring, and diagnostic functions through a digital display. 2 freezer bins: For all PHCbi ºC & 40ºC freezers a wide variety of storage solutions are available. From shelves to racks and / or bins. MANUAL DEFROST Manual defrost freezers provide stable temperature control and do not exhibit the transient temperature increases that can be associated with autodefrost type freezers. The MDFU73M is therefore ideal for storing your important, temperaturesensitive samples. STURD CABINET CONSTRUCTION WITH SUPERIOR INSULATION The integral foamed cabinet structure is extra strong and prevents cold air loss. RAPID TEMPERATURE RECOVER MAINTAINS UNIFORMIT The rapid pulldown speeds of PHCbi Biomedical freezers ensures that the effects of door openings are minimized. Uniform temperatures are maintained throughout the chamber through direct cooling with a full cold wall design. The inner chamber temperature offers outstanding uniformity and stability without temperature spikes. 2 Model: MDFU73MPE 2

Models: MDFU73MPE I MDFMU0HPE I MDFMU500HPE I MDFU542PE I MDFU443PE Inverter technology saves energy and enhances sample security With the introduction of inverter technology, PHCbi is offering exceptional performance and energy efficiency in our latest Biomedical freezers. While conventional freezers use single speed compressors which cycle on and off, PHCbi's latest Biomedical freezers contain inverter compressors that can run at different speeds to maximise cooling performance under different conditions. INVERTER TECHNOLOG LEADS TO COST EFFICIENC The start up of a compressor is the most energy consuming part of the cycle. The ability of the inverter compressor to run at lower speeds has the advantage that the compressor will not turn off and on as often thus saving energy and reducing wear. INVERTER TECHNOLOG LEADS TO SAMPLE SAFET The intelligent control of the inverter compressor optimizes running speed for the conditions. When the inverter compressor is running as normal it will stay on for longer than a conventional compressor but at a minimal speed. This reduces the power consumption and keeps freezer temperatures stable. When the door has been opened the compressor will run at maximum capacity to bring the temperature inside the freezer back down to set value quickly before resuming a normal cycle again. Compressor speed (rpm) Unit starting up Before door open Door open After door open Time compressor NATURAL REFRIGERANTS Natural hydrocarbon (HC) refrigerants provide more efficient cooling due to their high latent heat of evaporation. As a result the refrigeration system offers greater energy efficiency. With an exceptionally low global warming potential, natural refrigerants are also better for the environment. The freezers provide effective storage of lifesaving vaccines and samples for diagnosis in the medical field. Model: MDFMU500HPE Model: MDFMU0HPE 3

TwinGuard ULT Freezers TwinGuard Ultra Low Temperature Freezers with Dual Cooling Technology offer the highest level of security for highvalue samples. Alongside exceptional easeofuse and data monitoring, the Dual Cooling System provides the highest level of protection through the use of two independent refrigeration systems. If one system unexpectedly fails, the other can maintain the freezer s temperature uniformly in the 70 C range. Developed for use with conventional inventory racks and boxes, the TwinGuard Series is ideal for storage of sensitive, highvalue samples. SCIENTIFIC APPLICATIONS Temperature sensitive samples such as therapeutics and biospecimens. Samples needing to retain viability such as stem cells, engineered tissue, organs, vaccines, hybrodmas, cancer cells or fibroblasts. Longitudinal study samples. Important medical research samples. Valuable pharmaceutical products. Clinical trial samples. Pathogenic samples within high security laboratories. In the case of unexpected failure of one of the cooling circuits, the other circuit will maintain the freezer continuously in the 70ºC range. MEDICAL DEVICE DIRECTIVE MDFDU702VX, MDFDU502VX, MDFDC500VX and MDFDC700VX Freezers are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of storing human cells, organs, plasma and DNA. Model: MDFDC700VXPE Model: MDFDU702VXPE 4 Models: MDFDU702VX MDFDU502VX

Models: MDFDU502VXPE I MDFDU702VXPE I MDFDC500VXPE I MDFDC700VXPE PRESERVE SAMPLE INTEGRIT FOR BETTER END PRODUCTS (TwinGuard) Uneven interior temperatures can lead to a loss in sample integrity. Freezers with uniform, stable temperatures and quick recovery times provide the best protection for your samples, ensuring reliable preservation while guarding against degradation. TwinGuard FIGURE 2A MDFDU702VX; 9 POINT TEMPERATURE MAPPING DUAL COOLING SSTEM Within TwinGuard's independent systems, efficient ultralow cooling is achieved through two independent evaporator circuits surrounding the interior chamber. Two independent evaporator circuits FILTERLESS DESIGN The filterless construction of the freezers reduces routine maintenance time by eliminating the need for regular cleaning of filters. SUPERIOR FOOTPRINT PHCbi ultralow temperature freezers with spacesaving VIP insulation offer outstanding energy efficiency, whilst delivering exceptional cooling performance and durability for storing valuable research and clinical samples. 86ºC A B The Dual Cooling System offers the highest level of security through the use of two independent refrigeration systems. If one system unexpectedly fails the other can maintain the freezer at the 70ºC range. Dual Cooling System Upright freezers 5

Meeting your freezer storage needs ENHANCED USE & INTELLIGENT SECURIT LCD touch panel (MDFDU502VXPE and MDFDU702VXPE) The freezers are managed and monitored by an integrated microprocessor controller with a comprehensive alarm system and diagnostic functions. Status and control of parameters are accessible via an LCD information centre. The EZlatch, on the upright models, makes access to stored samples even easier. A colour LCD touch panel allows full user control, even with gloved hands, while the USB port makes transferring logged data to a PC convenient. INDUSTR FIRST INTELLIGENT ECO MODE OPERATION The TwinGuard series freezer can be set to Normal or ECO mode operation, depending on the requirements of the user. Although both refrigeration systems are completely independent, ECO mode establishes an overlapping cycle to significantly reduce energy consumption while maintaining optimum interior uniformity for protection of high value materials. Normal mode maintains the most repeatable, cycling wave form for the strictest of GMP applications. ECO MODE OPERATION IMAGE CHAMBER TEMP. COMPRESSOR A COMPRESSOR B Pulldown Pattern Pattern 2 NORMAL MODE OPERATION IMAGE CHAMBER TEMP. COMPRESSOR A COMPRESSOR B Pulldown Stable temperature Stable temperature Pattern 3 COMP A/B COMPLEMENTAR OPERATION COMP A/B SIMULTANEOUS ONOFF OPERATION 6

Models: MDFDU502VHPE I MDFDU702VHPE I MDFC8VPE VIP ECO ULT Freezers At PHCbi, we have designed freezers that are both efficient and reliable without compromising performance. A unique heat exchanger technology decreases energy usage and makes our freezers 40% more efficient than leading competitors. EFFICIENC The VIP ECO Series also uses vacuum insulation panel (VIP) technology reducing wall thickness by around 50%, achieving % more storage capacity, and reducing the average cost per box stored. Leveraging the power of natural hydrocarbon refrigerants also allows the VIP ECO ULT freezers to use smaller compressors, due to their greater efficiency. The natural hydrocarbon refrigerants combined with VIP insulation technology also help the environment by reducing the carbon footprint with up to 40% fewer emissions. VIP CHEST Freezer Model: MDFDU702VHPE PRODUCT FEATURES Model: MDFC8VPE Alarm lamp and buzzer offer secure warning of power failure or abnormal temperature increase. High and low temperature warning provides an audible and visual alarm when the temperature deviates more than ±5ºC to ±20ºC (adjustable) from the set point. Alarm ringback function ensures the buzzer will resume operation should alarm conditions continue after it is silenced. Microprocessorcontrolled filterclog check function protects the refrigeration circuit. The rugged, onehanded outer door latch allows a padlock to be used to securely protect valuable samples. Control panel with digital display for easy operation. PHCbi s patented VIP PLUS technology has resulted in a revolutionary vacuum insulation cabinet construction that reduces wall thickness by approximately one half and achieves up to % more storage capacity than conventionally insulated freezers of the same footprint. Single compressor system achieves an approximately 40% reduction in power consumption and enables lownoise operation. 7

Models: MDFC256VANPE Cryogenic Freezers Cryogenic freezers are wellknown for maintaining uniform temperatures at 50ºC for the reliable, longterm preservation of cells and tissue. With thin vacuum insulation panel (VIP) walls, the MDFC256VAN cryogenic freezer can achieve more storage capacity than a conventionally insulated freezer without increasing footprint, while also maintaining superior temperature uniformity. CROGENIC FREEZERS PROMOTE SAMPLE STABILIT A uniformity of +/5ºC in PHCbi mechanically refrigerated cryogenic freezers is far superior to the toptobottom temperature uniformity provided by liquid nitrogen vapour phase storage, without the concern of crosscontamination often associated with liquid nitrogen (liquid phase storage). Recrystallization mechanism 80ºC ºC Recrystallization Point 50ºC Hexagonal crystal Cubic crystal Amorphous ice crystal Model: MDFC256VANPE Liquid Nitrogen freezer (Traditional vapour phase) Cryogenic MDFC256VAN mechanically refrigerated cryogenic freezer Comparison of temperature distribution in a liquid nitrogen freezer (vapour phase) and the MDFC256VAN mechanically refrigerated cryogenic freezer. The graph shows temperatures at different locations within the chamber. This data demonstrates that 00% of the MDFC256VAN storage space maintains uniform storage temperatures safely below ºC, while temperature in the LN2 vapour system is dependent on storage location. 8

Models: CBS Isothermals CBS Isothermals The sample storage area is cooled by a liquid nitrogen jacket surrounding the stainless steel interior, and by nitrogen vapour entering the freezer from the jacket via directional vents. This patented technology provides exceptional temperature uniformity in the 90ºC range, allowing the full freezer capacity to be used with confidence. The circulation of vapour within the freezer also results in less cold air loss during lid opening and improved visibility. This allows fullwidth lids to be used providing quick, unrestricted access to sample racks. With no liquid nitrogen in the storage area, samples can be stored safely in the 90ºC range without the risk of crosscontamination through liquid nitrogen. Model: V00AB/C Standard square rack configuration V500AB Vacuum insulation Temperature controlled storage area Model: V5000EH AB/C Liquid nitrogen envelope KE ADVANTAGES ) Dry storage freezer. 2) Unique patented liquid nitrogen jacket allows for no liquid in sample storage space and improves user safety. 3) Reduced exposure to room temperatures. 4) Superior temperature uniformity. 5) No risk of crosscontamination through liquid nitrogen contact. 6) Carousel is rotated from outside of the freezer eliminating risk of injury or temperature fluctuations. 7) Manufactured to ISO 3485 standards. 9

Models: MIR54PE I MIR254PE I MIR554PE MIR Cooled Incubators These MIR incubators offer precise, repeatable control of prograable temperatures which are essential for the culturing of microbiological and environmental samples and they can also be used to provide temperature controlled storage environments. PROCESS EFFICIENC Model: MIR554PE Model: MIR54PE INTUITIVE OPERATION WITH LCD DISPLA Easy operability with LCD display and pop up menu. 24hour Clock mode and Timer mode are selectable. Combination of multiple programs in Join function. Prograable operation start date and hour. Operation data can be autorecorded and graphically displayed. Chamber light ONOFF control. METICULOUS DESIGN FOR COMFORTABLE OPERATION The cooled incubators are crafted with a comfortable rounded corner design and offer a reversible door for a choice of left or righthand door opening. Low vibration setting is also available depending on the sample to be cultured (reversible door is unavailable for MIR554). HIGHPRECISION TEMPERATURE ENVIRONMENT Wide temperature control range from 0ºC to +60ºC With a wide temperature range from 0ºC to +60ºC, MIR Cooled Incubators allow a full range of precise experiments, culturing and storage environments. Precise microprocessor temperature control MIR Cooled Incubators incorporate a high precision microprocessor temperature control combined with a heater PID and compressor on/off system. 20

Models: MCO70AICPE I MCO2AICPE I MCO80ICPE IncuSafe CO 2 Incubators IncuSafe CO 2 Incubators, with PHCbi s innovative technologies, offer outstanding quality in performance to maximise cell culture productivity and provide optimum results with reproducibility to meet the demands of todays varied cell culture applications. ACTIVE BACKGROUND DECONTAMINATION Proactive contamination control is achieved through a combination of a copperenriched stainless steel interior (incu safe ) and an optional ultraviolet light. The copperenriched stainless steel interior surface combines the germicidal properties of copper and the anticorrosive nature of stainless steel. CONSISTENT AND UNIFORM ENVIRONMENT FOR CELL GROWTH PHCbi combines Direct Heat and Air Jacket heating system that surrounds the inner walls with a natural convection airflow to achieve exceptional temperature uniformity within the chamber. Combined with a dual Model: MCO70AICPE infrared sensor for unprecedented control over CO 2 gas levels, the IncuSafe incubator provides a stable environment for cell growth even with multiple door openings daily. MCO80IC REACH IN CO 2 INCUBATOR Large capacity, 85 litre CO 2 incubator with adjustable shelving provides flexibility in use. Accoodates roller bottle apparatus, 5 bottles wide x 7 bottles high (requires optional Mounting Ramp Kit, MCO80RBS). Full view, double paned glass door allows clear observation of cultured samples. Large LED digital display and keypad for greater visibility and ease of setup. Model: MCO80ICPE 2

Models: MCO70AICPE I MCO2AICPE I MCO70MPE We have designed our incubators with ease of use and efficiency in mind. By delivering a user friendly cell culture incubator with rapid systems and processes PHCbi can help make your work as simple as possible. MORE SPACE FOR MORE CULTURES In a laboratory environment it is important to make the most of all the space available. With new integrated shelf supports the IncuSafe MCO70AIC CO 2 incubators provide space for up to 25% more culture vessels.* * Compared to previous PHCbi 70 litre CO 2 incubators. IncuSafe incubator design delivers exceptional ease of use, effortless maintainance, and outstanding performance with multilevel contamination control. USB PORT Optimise cell culture protocols and adhere to standard operating procedures by conveniently transferring data to a USB memory stick to pass on to a PC. Logged parameters include chamber temperature, CO 2 level, door open status and alarms. INTEGRATED SHELF SUPPORTS The MCO70AIC, MCO70M and MCO2AIC incubators have less removable parts than the traditional incubators. The new interior design with integrated shelf supports makes it easier to clean which saves valuable time and reduces risk of contamination. MEDICAL DEVICE DIRECTIVE MCO70AIC MCO2AIC MCO70M Series are certified as a Class IIa Medical Device (93/42/EEC and 2007/47/EC) for medical purposes of culturing cells, tissues, organs and embryos. MCO70M MULTIGAS INCUBATOR WITH PRECISION 0 2 CONTROL The latest IncuSafe MCO70M multi gas incubator offers the most precise regulation of oxygen and other gasses, while maintaining superior temperature uniformity, contamination control, and usability. The Dual Infra Red sensor achieves ultrafast CO 2 recovery without overshoot, even following multiple door openings whilst the unique solid Zirconia O 2 sensor delivers precise control of physiological oxygen levels to simulate in vivo conditions. 22

ULTRAVIOLET LIGHT AND COPPER ENRICHED STAINLESS STEEL INTERIOR REDUCE THE CHANCE OF CONTAMINATION To further prevent contamination in the incubator, PHCbi implemented a unique SafeCell ultraviolet (UV) system. SafeCell UV technology uses a prograable ultraviolet lamp that sterilises air and the humidity water pan without affecting cell cultures. It inhibits the growth of all contaminants including mycoplasma without costly HEPA filter air scrubbers which are ineffective on particles less than 0.3 microns. RAPID HDROGEN PEROXIDE DECONTAMINATION REDUCES EXPERIMENTAL DOWNTIME With PHCbi s hydrogen peroxide technology, achieve complete decontamination 8X faster than conventional high heat methods. The cycle completes in just 3 hours including the post ultraviolet conversion of H 2 O 2 into water and oxygen for easy cleanup. This allows researchers to get back to their cell culture work the same day and allows companies to achieve faster drug discoveries. ADVANCED TOUCH SCREEN HARMLESS H 2 O + O 2 SafeCell UV CONTAMINANT DAMAGE Remaining H2O2 and hydroxyl radicals CONTAMINANT CELL CONTAMINANT DEATH 2 OH OH initiates chain reaction of electron stealing Model: MCO2AICPE A color LCD Touch screen delivers full control over the incubator. Control can be performed with gloved hands. H 2 O 2 separates in two hydroxyl radicals OH + OH H 2 O 2 can obtain an electron from an organic source 23

Validation & qualification SOLUTIONS Keeping up with evolving regulations that are constantly becoming stricter can be a daunting task. When it comes to your laboratory equipment it is important to know that it will pass compliance checks and that the manufacturer has years of experience in validation training and services. PHCbi is a vertical component manufacturer that can provide turnkey solutions for validation and qualification in accordance with all current regulations and specific customer requirements and applications. Validation Solutions Turn key solutions available for: l l l l l l l l Ultralow freezers Cryogenic freezers Medical freezers Pharmaceutical refrigerators Incubators Ovens Autoclaves Environmental test chambers PHCbi VALIDATION SOLUTIONS Inhouse Third party Manufacturer Equipment experience Broad based Broad based Most PHCbi specific experience Up to date technical info General knowledge General knowledge Direct updates Unexpected service issues Time delay Time delay Iediate solutions Time consuming More prep. time More prep. time Most experience Knowledge of industry standards High level Broad based Best applicable knowledge 24

INSTALLATION AND OPERATIONAL QUALIFICATION (IOQ) PHCbi offers onsite validation of PHCbi manufactured equipment via Installation and Operational Protocol (IOQ). ) INSTALLATION QUALIFICATION (IQ) Verifies and documents the equipment installation to be compliant with the manufacturer s requirements and specifications. 2) OPERATIONAL QUALIFICATION (OQ) Verifies and documents the full functional operation of the installed equipment (as specified by PHCbi or other OEM supplied equipment). Temperature performance will be mapped over a continuous 24hr period. Data produced will be compared with manufacturer s published equipment specification. Product specific parameters such as the CO 2 /O 2, %RH, etc can be included within the relevant equipment IOQ protocol. 3) PROCESS QUALIFICATION (PQ) Usually conducted and performed by the enduser as the equipment will be in an environment where specific user conditions apply, i.e., the customer s actual production or product processing area. The PQ will make reference to customer specific Standard Operation Procedures documents (SOPs). 4) TEMPERATURE MAPPING Offered for customers wishing to verify actual equipment performance as installed. This is also available for nonphcbi equipment. 5) FACTOR ACCEPTANCE TESTING (FAT) Indepth factory acceptance testing covers alarms, temperature and CO 2 stability, and temperature recovery. This service can be customised to SOPs. Validation by Model MDF50ºC Freezers MDF86ºC Freezers MDFºC Freezers MBR Blood Bank Refrigerators MPR Pharmaceutical Refrigerators MIR Incubator Series MCO CO 2 &O 2 /CO 2 Incubators MLS Top Loading Autoclaves MLR Environmental Test Chamber CBS Standard LN 2 Freezers THERMAL VALIDATION PHCbi also provides a thermal validation solution specifically designed to conform with new FDA data protection guidelines (2 CFR Part ) and meet international and European cgmp requirements for inspection of pharmaceutical, biotechnology, and medical device (EN285, EN554), manufacturing. SERVICES PHCbi validation services by model Temp. CO 2 O 2 %RH Lighting Pressure (Lux/Par) 4 4 4 4 4 Measurement of temperature profiles, CO 2, O 2, %RH, lighting, and pressure Reduced Setup Time Automatic Sensor Calibration Data Analysis System Design 4 4 4 4 4 4 4 4 4 4 4 4 INSTALLATION, CALIBRATION & MAINTENANCE In order to trace and keep an accurate record of performance of your lab equipment, a regular schedule of calibration and preventive maintenance is required. PHCbi offers the following services: Coissioning/Setup/Installation Calibration Onsite Protocol Execution Warranty response Factory Acceptance Testing Custom Validation Protocols 25

SPECIFICATIONS MBR Blood Bank Refrigerators Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Net weight (approx) Capacity Performance Temperature setting range Control Controller Display Temperature recorder Temperature sensor Refrigeration Cooling method Defrost method Refrigerant Insulation Construction Exterior material Interior material Outer doors Outer door lock Inner door Shelves litres 450ml bags ºC MBR5GRPE 600 x 680 x 835 520 x 490 x 50 2 20 47 4 +/.5 Microprocessor LED MTRG04 (included) 2 bottles with thermistor sensor Forced air Fully automatic PUF HFC, Double layer glass window 2, Acrylic 5, Stainless steel MBR705GRPE 770 x 8 x 955 650 x 697 x 500 622 360 23 4 +/.5 Microprocessor LED MTRG04 (included) 2 bottles with thermistor sensor Forced air Fully automatic PUF HFC, Double layer glass window 3, Acrylic 6, Stainless steel MBR405GRPE 440 x 8 x 950 320 x 697 x 500 720 35 4 +/.5 Microprocessor LED MTRG04 (included) 2 bottles with thermistor sensor Forced air Fully automatic PUF HFC 2, Double layer glass windows 6, Acrylic 2, Stainless steel Drawers Max. load per shelf/drawer Max. load total Access port position diameter Casters Interior light Alarms Power failure High temperature Low temperature Door open Electrical and Noise Level Power Supply Noise Level 2 Options Temperature recorders Temperature chart recorder chart paper recorder housing Circular type chart paper Ink pen recorder housing External mounting power failure alarm Ø db(a) 20 00 Left 4 Fluorescent VBR VBR VBR VB 2V 50Hz single phase 4 Included RPG04PW PGRPW 40 240 3 Left / right / top 4 Fluorescent VBR VBR VBR VB 2V 50Hz single phase 45 Included RPG04PW PGRPW 40 480 2 Left / right 4 Fluorescent VBR VBR VBR VB 2V 50Hz single phase 48 Included RPG04PW PGRPW 26 Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Nominal value Bacround noise 20dB 3) Remote alarm comes with optional power failure alarm MPR48BPW 4) Double pane glass window with heat reflecting film

Models: MBR5GRPE I MBR705GRPE I MBR405GRPE I MPR72(R)PE I MPR4(R)PE MPR54(R)PE I MPR04(R)PE MPR Pharmaceutical Refrigerators MPR Sliding Door Pharmaceutical Refrigerators MPR72PE MPR72RPE MPR4PE MPR4RPE MPR54PE MPR54RPE MPR04PE MPR04RPE 684 74 770 x 8 x 955 650 x 70 x 500 67 93 440 x 8 x 950 320 x 70 x 500 364 359 248 287 489 4 900 x 600 x 790 800 x 465 x 0 486 47 800 x 600 x 790 700 x 465 x 0 033 029 246 258 2 ~ 23 2 ~ 23 2 ~ 4 2 ~ 4 Microprocessor LED Microprocessor LED Microprocessor LED Microprocessor LED Thermistor Thermistor Thermistor Thermistor Forced cool air circulation Forced type (cycle defrost), fully automatic HFC PUF Forced cool air circulation Forced type (cycle defrost), fully automatic HFC PUF Forced cool air circulation Forced type, fully automatic HFC PUF Forced cool air circulation Forced type, fully automatic HFC PUF door, double pane glass, self closing 2 doors, double pane glass, self closing Stainless steel 2 sliding doors 4) Stainless steel 2 sliding doors 4) 4 wire shelves, polyethylenecoated 50 200 5 coated steel drawers 40 200 8 wire shelves, polyethylenecoated 40 320 0 coated steel drawers 40 400 5 wire shelves, polyestercoated 50 250 5 wire shelves + 5 sliding racks 50 + 20 350 0 wire shelves, polyestercoated 50 500 5 wire shelves + 0 sliding racks 50 + 20 450 3 Left/right/top 4 Fluorescent 3 Left/right/top 4 Fluorescent Left 4 Fluorescent Left 4 Fluorescent VBR (Optional) VBR VBR VB VBR (Optional) VBR VBR VB VBR (Optional) VBR VBR VB VBR (Optional) VBR VBR VB 2V 50Hz single phase 4 2V 50Hz single phase 42 2V 50Hz single phase 42 2V 50Hz single phase 42 MTR062LHPE RP06PW MPRSPW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) MTR062LHPE RP06PW MPRSPW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) MTR062LHPE RP06PW MPRSPW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) MTR062LHPE RP06PW MPRSPW MTRG04CPE RPG04PW PGRPW MPRS7PW MPR48BPW (VB) 3) 27

SPECIFICATIONS Biomedical ECO 40ºC Plasma Freezer Biomedical 40ºC Freezers Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Capacity Net weight (approx) Performance Cooling performance 2) Temperature setting range Temperature control range 2) Control Controller Display Temperature sensor Refrigeration Cooling method Compressor Refrigerant Insulation material Insulation thickness Construction Exterior material Interior material Outer door Outer door lock Shelves Containers / baskets Max. load per shelf / container / basket Max. load total Access port position diameter Interior fluorecent lamp Casters Alarms Power failure High temperature Low temperature Filter Door open Electrical and Noise Level Power Supply Noise Level 5) Options Storage systems litres 2 boxes ºC ºC ºC W W Ø db(a) MDFU542HPE 804 x 772 x 802 658 x 607 x 272 482, 280 FFP packs (0ml) 224 34 40 2) 8 ~ 45 20 ~ 40 2) Microprocessor nonvolatile memory LED Thermistor Direct 400 HFC PUF 70 Stainless steel 2 4 (fixed) 4/6/0 00 Back 4 (2 levelling feet) VBR VBR VBR 2V 50Hz single phase 42 MDFU443PE 800 x 832 x 80 640 x 65 x 090 426, 0 FFP packs (0ml) 256 23 40 3) 5 ~ 44 5 ~ 4 3) Microprocessor nonvolatile memory LED Thermistor Cascade + forced air circulation H:400/L:750 HFC PUF 80 Stainless steel 5 50 200 Left 40 4 (2 levelling feet) VBR VBR VBR VB VB 2V 50Hz single phase 5 Temperature recorders Circular type Chart paper Ink pen Recorder housing Continuous strip type Chart paper Ink pen Recorder housing External mounting power failure alarm MTRG85CPE RPG85PW PGRPW MPRS7PW MTR405LHPE RP40PW MPRSPW MTR405LHPE (40 ~ +4ºC range) or MTR85H (00 ~ +50ºC range) RP40PW 8) or RPG85PW 9) DF38FPPW 9) MPRSPW 8) 28

Models: MDFU542HPE MDFU443PE MDFU73MPE MDFMU0HPE MDFMU500HPE MPR75FPE Biomedical ºC Freezers Biomedical ECO ºC Freezers MPR Pharmaceutical Refrigerators with Freezer MDF73MPE MDFMU0HPE MDFMU500HPE MPR75FPE 770 x 8 x 955 650 x 700 x 520 690 384 52 60 x 598 x 620 490 x 486 x 290 274 50 76 800 x 772 x 802 658 x 607 x 272 482 224 24 900 x 75 x 90 80 x 65 x 894 (Ref), 770 x 552 x 422 (Frz) 45/76 (Ref/Frz) 68 2) 8 ~ 35 20~ 2) 2) 8 ~ 35 20 ~ 2) +5 / +2 to +4/ 35 to 5 +2 to +4/ to 20 Microprocessor, nonvolatile memory LED Thermistor Microprocessor, nonvolatile memory LED Thermistor Microprocessor, nonvolatile memory LED Thermistor Direct 400 HFC PUF 60 60 Direct 250 (inverter control) HC 70 Fan forced air circulation (Ref) / Direct cooling (Frz) 7) HFC PUF 40 / 60 4 (fixed) Optional 50 200 Left 4 (2 levelling feet) ABS resin Styrol resin 2 4 (fixed) 4 (fixed) 4/0/ 4/6/0 U:/L:20 80 00 Left Back 4 (2 levelling feet) Painted Steel Painted Steel (Ref/Frz) 4, glass window (2), 2 3 (Ref) / 2 (Frz) 25 / 5 (Ref/Frz) 05 2 Back LED 4 VBR VBR VBR VB VBR 4) VBR 4) VBR 4) VBR VBR VBR VB 2V 50Hz single phase 42 2V 50Hz single phase 40 2V 50Hz single phase 43 MDFT07SCSW, Set of 2 containers MDFT07STSW, Set of 3 shelves MTRG85CSE RPG85SW PGRSW MPRS7SW MTR405LHPE MTRG85CPE RPG85PW PGRPW MPRS470TPW MPRS7PW MTR405LHPE MTRG3504CPE RPG3504PW PGRBPW MTR062LHPE (Ref) / MTR405LHPE (Frz) RP40SW MPRSSW RP40PW MPRSPW MPR48BPW 6) RP06PW (Ref) / RP40PW (Frz) MPRSPW Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Air temperature measured at freezer centre, ambient temperature +ºC, no load 3) Air temperature measured at freezer centre, ambient temperature +35ºC, no load 4) Remote alarm comes with optional power failure alarm MPR48BPW 5) Nominal value Bacround noise 20dB 6) Requires MPR48BPW 7) Defrost method: Cyclical defrost (Ref) / Manual (Frz) 8) For use with MTR405LHPE 9) For use with MTR85HPW 29

SPECIFICATIONS TwinGuard Upright Freezers TwinGuard Chest Freezers Model Number Dimensions External dimensions (WxDxH) ) Internal dimensions (WxDxH) Volume Capacity Net weight (approx) Performance Cooling performance 2) Temperature setting range Temperature control range 2) Control Controller Display Temperature sensor Refrigeration Refrigeration system Highstage compressor Highstage refrigerant Lowstage compressor Lowstage refrigerant Insulation material Insulation thickness Construction Exterior material Interior material Outer door lock Inner door/lid Shelves Max. load per shelf Max. load total 3) Vacuum release port Access port position diameter Casters Alarms Power failure High temperature Low temperature Filter Door open Electrical and Noise Level Power Supply Noise Level 4) Options Liquid CO 2 backup Liquid N 2 backup Temperature recorders Circular type Chart paper Ink pen Continuous strip type Chart paper Ink pen Recorder housing Drawers Small inner door kit Small inner door kit Small inner door kit litres 2 boxes ºC ºC ºC W W Ø db(a) set of 2 set of 5 set of 4 MDFDU502VXPE 790 x 882 x 993 6 x 600 x 400 528 384 276 45 MDF5ID5PW MDF5ID4PW 6) 86 50 ~ 90 50 ~ 86 MDFDU702VXPE 0 x 882 x 993 870 x 600 x 400 729 576 320 Microprocessor nonvolatile memory LCD Pt000 Independent DualCooling 2 x 00 HFC mixed PUF / VIP PLUS 80 2 (insulated) 3 50 3 Back x, bottom x 2 7 4 (2 levelling feet) VBR VBR VBR Filterless design VB 2V 50Hz single phase 52 MDFUB7PW MTRG85CPE RPG85PW 8) PGRPW MTR85HPW RP85PW 8) DF38FPPW MDFS85PW 55 MDF7ID5PW MDF7ID4PW 7) MDFDC500VXPE 200 x 845 x 070 90 x 640 x 756 575 46 328 MDFDC700VXPE 20 x 845 x 070 480 x 640 x 756 75 520 358 86 50 ~ 90 50 ~ 86 Microprocessor nonvolatile memory LCD Touch Screen Pt000 Independent DualCooling 2 x 00 HFC mixed PUF / VIP PLUS 70 / 35 Stainless Steel 3 (Styrofoam) Back 7 6 (3 levelling feet) VBR VBR VBR Filterless design VB 2V 50Hz single phase 52 MDFUB5PW MTRG85CPE RPG85PW PGRPW MTR85HPW RP85PW DF38FPPW MDFS85PW Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) Air temperature measured at freezer centre, ambient temperature +ºC, no load 3) Max. load is the total of the load distributed over all shelves (3) and chamber bottom surface.the weight is the maximum load for chamber inside and excludes load on casters equipped with product. 4) Nominal value. Bacround noise 20dB

Models: MDFDU502VXPE MDFDU702VXPE MDFDC500VXPE MDFDC700VXPE MDFDU502VHPE MDFDU700VHPE MDFC8VPE MDFC256VANPE VIP ECO Upright Freezers VIP Chest Freezers Cryogenic Freezer MDFDU502VHPE MDFDU702VHPE MDFC8VPE MDFC256VANPE 790 x 870 x 990 6 x 600 x 400 528 384 246 0 x 882 x 993 870 x 600 x 400 729 576 278 550 x 685 x 945 405 x 490 x 425 84 42 67 7 x 765 x 00 760 x 495 x 65 23 50 38 86 50 ~ 90 50 ~ 86 80 55~90 60 ~ 80 50 25 ~ 52 25 ~ 50 Microprocessor nonvolatile memory LCD Touch Screen Pt000 Microprocessor nonvolatile memory LED Pt000 Microprocessor nonvolatile memory LCD Pt000 Cascade 750 HC 750 HC PUF / VIP PLUS 80 Autocascade 400 HFC mixed PUF / VIP PLUS 70 Cascade with autocascade lowstage 00 HFC 00 HFC mixed PUF / VIP PLUS 35 45 2 (insulated) 3 50 55 00 Aluminium 2 207 2 ( automatic, manual) 3 Back x / bottom x 2 7 4 (2 levelling feet) 2 Back/bottom 7 4 (2 levelling feet) Right 40 6 (3 levelling feet) VBR VBR VBR VB VB VBR VBR VBR Filterless design VBR VBR VBR VB VB 2V 50Hz single phase 52 2V 50Hz single phase 47 2V 50Hz single phase 5 MDFUB7PW CVKUB4PW CVKUBN2PW Supplied as standard MDF5ID5PW MDF5ID4PW 6) MTRG85CPE RPG85PW 8) PGRPW MTR85HPW RP85PW 8) DF38FPPW MDFS85PW MDF7ID5PW MDF7ID4PW 7 ) MTRG85CPE RPG85PW PGRPW MTR85HPW RP85PW DF38FPPW MDFS85PW MTR55HPW RP55PW DF38FPPW MDFS50PW 5) Installation of small inner door kit may affect usable storage capacity. 6) Usable storage capacity will be 320 x 2 boxes with installation of MDF5ID5PW and additional shelf 7) Usable storage capacity will be 480 x 2 boxes with installation of MDF7ID5PW and additional shelf. 8) Requires sensor cover MTRDU700SFPW. 3

SPECIFICATIONS Models: CBS Isothermals Isothermal 90ºC Dry Storage Freezers Model Number Liquid nitrogen capacity Dimensions External dimensions (WxDxH) Usable interior height Usable interior diameter Weight empty Weight full Maximum capacity Max. vial capacity (2ml)** Max. blood bag capacity (50ml)** litres V500AB 660 x 939 x 43 736 534 48 74 900 434 V00AB 70 939 x 29 x 206 736 787 272 327 2200 20 V00ABEH 89 939 x 29 x 473 940 787 295 367 25500 280 V5000AB 93 29 x 37x 320 736 06 425 500 400 936 V5000ABEH 40 29 x 37 x 473 864 06 453 566 46500 2208 ** Capacity is subject to rack type Isothermal Carousel Model Number Liquid nitrogen capacity Dimensions External dimensions (WxDxH) Usable interior height Usable interior diameter Weight empty Weight full Maximum capacity Max. vial capacity (2ml)** Max. blood bag capacity (50ml)** litres V00AB/C 70 939 x 29 x 686 736 272 327 6800 852 V00ABEH/C 89 939 x 29 x 384 889 736 288 36 2000 36 V5000AB/C 93 94 x 372 x 257 737 978 425 499 36400 722 V5000ABEH/C 40 94 x 372 x 384 83 978 452 566 42000 968 ** Capacity is subject to rack type Medical Device Directive PHCbi has become one of the first companies in our industry to introduce Medical Device certification to underline our strong coitment to product design, quality and safety. In 200, PHCbi was awarded certification by TÜVSüd to manufacture blood bank refrigerators, freezers and incubators as Class IIa Medical Devices according to the directives 93/42/EEC and 2007/47/EC. At the same time our quality systems were updated to the latest ISO900 and ISO3485 standards. The use of refrigeration products and cell culture incubators for the preservation and cultivation of cells and tissues for human use in transfusion, regenerative medicine and cell therapy is set to expand. In anticipation of these developing technologies and possible changes in the regulatory landscape, PHCbi began to introduce Medical Device certified products in 20. The first models to be certified include the: MDFDU0H, MDFU55V, MDFDU502VH, MDFDU702VH, MDFDU702VX, MDFDC502VX, MDFDU900VPE MDFU542H, MDFU443 MBR5GR, MBR705GR, MBR405GR MCO70AIC, MCO2AIC, MCO70M PHC Corporation, Gunma Factory is certified for: Quality management system: ISO900 Medical devices quality management system: ISO3485 023 32

SPECIFICATIONS Models: MIR54PE I MIR254PE I MIR554PE MIR Cooled incubators Model Number External Dimensions (W x D x H ) Internal Dimensions (W x D x H) Volume liters Net Weight Performance Temp control range and fluctuation ºC Temperature uniformity ºC Performance ambient temperature ºC Control Temperature Sensor Refrigeration Insulation material Insulation thickness Compressor Refrigerant Cooling method Construction Exterior material Interior material Outer door Outer door lock Reversible door Inner door Shelves Max. load per shelf Max. total load Access port position diameter Ø Interior fluorescent lamp Alarms Power failure High temperature Low temperature Door open Electrical and noise level Power supply V Frequency Hz Noise level 3) db(a) Options Stacking kit Door padlock bracket Additional illumination kit Inner doors Door window blanking plate MIR54PE MIR254PE MIR554PE 700 x 580 x 08 620 x 368 x 555 23 78 700 x 580 x 68 620 x 368 x 088 238 08 800 x 832 x 80 640 x 550 x 60 406 95 0 ~ +60 (AT; +5 ~ +35, no load), ±0.2 with Heater PID control (SV 50), ±.5 with Compressor control (SV 5) 40 50 PID control: 7ºC above AT for MIR54/254; 0ºC above AT for MIR554 ±0.5 SV (35) 20, no load Thermistor PUF 40 250 80 250 R34a N R404A Forced air circulation SS SUS4 MIRLP option N R404A N 2 small inner doors (MIR55ID option) MIRLP option 3 20 6 left side 5 20 00 left side 40, 5, with MIRL5PE 2) option 5 50 250 2 left and right side 4 MIRS54SBPW MIRLPPW MIRL5PE MIR54BPPW (R = Remote Alarm, V = Visual Alarm, B = Buzzer Alarm) VBR VBR VB 2 50 44 MIRLPPW MIRL5PE MIR254BPPW R 45 MIRL5PE MIR55IDPW Notes: ) Exterior dimensions of main cabinet only, excluding handle and other external projections See dimensions drawings on website for full details 2) MIRL5PE operates between +2 C and +50 C 3) Nominal value. Bacround noise 20dB 33