CONTENTS FD SeriesLab Scale Freeze Dryer (Lyophilizer)... 3 LAB-Series Lab Freeze Dryer (Lyophilizer)... 9 FD Series Pilot scale automatic freeze dryer... 13 FD-P Series Process Freeze Dryer... 21 FD-FP series Vacuum Freeze Dryer (Lyophilizer)... 24
FDSERIESLab Freeze Dryer/Lyophilizer FD SeriesLab ScaleFreeze Dryer(Lyophilizer) DESCRIPTION Vacuum freezing dryer is widely used in the medical, pharmaceutical, biological, chemical and food and other fields, FD series is suitable for laboratory use or low-volume production to meet the requirements of most laboratories conventional lyophilization. FEATURES M icroprocessor control & LCD touch display which can display drying curve, vacuum, condenser temp., run time, ambient temperature. Pre-freezing function for samples. Large refrigerating capacity and slight noise of DANFOSS(SECOP) compressor with CFC-FREE refrigerant. 304 stainless steel of condenser, table-top, racks & shelves to ensure corrosion-resistant and easy to clean; shelves height adjustable. Transparent drying chamber is safe and easy to observe; Novel design, small size and easy operation; For water based samples, the -55 C condenser is the perfect choice with effective cost. For samples containing solvents or with low eutectic points, the - 80 C dual cascade refrigeration condenser provides maximum performance(optional). For labs that needs quick turn-around, electric heating defrost is optional. Nitrogen inflation valve is available. It includes the following types: Normal type, Top-press type, multi-manifold T type and multi-manifold Top-press type to meet the various requirements. Normal type suitable for bulk raw products like food, fruit, herbal medicine and other bio material, Toppress(stoppering) type suitable for vials comes with cap, to stoppering caps into the vials. CE/ISO 9001 13485 14001 certificated. FD-10 Bench-top type Model FD-10-R FD-10-MR FD-10-TP FD-10-MTP FD-10-MT Image Dry chamber size (D*H) Ф260 430mm Ф260 465mm Ф260 490mm Ф260 540mm / Total shelf area 0.12 m 2 0.12 m 2 0.08m 2 0.08m 2 / Shelf size(mm) Ф200*4pcs Ф200*4pcs Ф180 * 3pcs Ф180 * 3pcs / Shelf space height (mm) 70 70 70 70 / www.labfreez.com ~ 3 ~
FDSERIESLab Freeze Dryer/Lyophilizer Shelf number 4 pcs 4 pcs 3 pcs 3 pcs / Trays number 4 pcs 4 pcs 3 pcs 3 pcs / Ф12mm 920 Pcs 920 Pcs 560 Pcs 560 Pcs Vials load 24 ports Ф16mm 480 Pcs 480 Pcs 285 Pcs 285 Pcs capacity 430 480mm (H *L) Ф22mm 260 Pcs 260 Pcs 165 Pcs 165 Pcs Sample load capacity 1.2L 1.2L 0.8L 0.8L / Flask / 8 pcs / 8 pcs / Dry rack Included Included Included Included / Cold trap rack Included Included Included Included Included Condenser Temp. <-55 C (-80 C or even lower is optional) Cold trap size. Ф215 * 140 mm (Depth * Height) Ice remove capacity 3~4kg/24hours Cold type Air-cooled Defrost type Natural (Electric is optional) Ultimate Vacuum <5 Pa (empty ) Vacuum pump Included Pump rate 2L/S Install Power 970W Voltage 220v /50Hz or 110v /60Hz Dimensions 460*625* (370+430)(mm) Weight 100 kg 110kg 105kg 120kg 65kg FD-12 FLOOR TYPE Model FD-12-R FD-12-MR FD-12-TP FD-12-MTP FD-12-MT Image Dry chamber size (D*H) Ф260 430mm Ф260 465mm Ф260 490mm Ф260 540mm / Total shelf area 0.12 m2 0.12 m2 0.08 m2 0.08m2 / Shelf size (mm) Ф200*4pcs Ф200 * 4pcs Ф180 * 3pcs Ф180 * 3pcs / Shelf space height (mm) 70 70 70 70 / Ф12mm 920 Pcs 920 Pcs 560 Pcs 560 Pcs Vials load 24 ports Ф16mm 480 Pcs 480 Pcs 285 Pcs 285 Pcs quantity 430 480mm (H *L) Ф22mm 260 Pcs 260 Pcs 165 Pcs 165 Pcs Sample load capacity 1.2L 1.2L 0.8L 0.8L / Flask / 8 pcs / 8 pcs / Dry rack Included Included Included Included / Cold trap rack Included Included Included Included Included Condenser temp. <-55 C (-80 C or even lower is optional) Cold trap size Ф215 * 140 mm (Depth * Height) Ice remove capacity 4 Kg/24h Cold type Air-cooled www.labfreez.com ~ 4 ~
FDSERIESLab Freeze Dryer/Lyophilizer Defrost type Natural (Electric is optional) Ultimate Vacuum <5 Pa Vacuum pump Included Pump rate 2L/S Install Power 970 W Voltage 220v /50Hz or 110v /60Hz Dimensions 460 556 (720+465)(mm) Weight 120 kg 135kg 130kg 140kg 76 kg FD-18 FLOOR TYPE Model FD-18-R FD-18-MR FD-18-TP FD-18-MTP FD-18-MT Image Dry chamber size (D*H ) Ф300 445mm Ф300 465mm Ф300 540mm Ф300 570mm / Total shelf area 0.18 m 2 0.18 m 2 0.09 m 2 0.09 m 2 / 0.27 m 2 0.27 m 2 Shelf size (mm) Ф240 * 4pcs Ф240 * 4pcs / Ф200 * 3pcs Ф200 * 3pcs Ф240 * 6pcs Ф240 * 6pcs Shelf space height (mm) 70 70 / 70 70 50 50 1320 Pcs 1320 Pcs Ф12mm 990 Pcs 990 Pcs 24 ports 1980 pcs 1980 pcs T-manifold Vials load 740 Pcs 740 Pcs Ф16mm 555 Pcs 555 Pcs 430 480mm (H *L) capacity 1110 pcs 1110 pcs Flask rack: 360 Pcs 360 Pcs Ф22mm 270 Pcs 270 Pcs 610 600mm 540 pcs 540 pcs Sample load capacity 1.8L 1.8L 2.7L 2.7L 0.9L 0.9L Flask / 8 pcs / 8 pcs / Dry rack Included Included Included Included / Cold trap rack Included Included Included Included Included C ondenser Temp. <-60 C (-80 C or ev en low er is optional) Cold trap size Ф270 * 400 mm (Depth * H eight) Ice capture capability 6 Kg/24h Cold type Air-cooled Defrost type Natural (Electric is optional) Ultimate Vacuum <5 Pa Vacuum pump Included Pump rate 4L/S Pow er 1400W Voltage 220v /50Hz or 110v /60Hz Dimensions 540 610 (963+445)(mm) www.labfreez.com ~ 5 ~
FDSERIESLab Freeze Dryer/Lyophilizer Weight 170 kg 185kg 185kg 195kg 105 kg Standard Configuration Stainless steel condenser with opening, stainless steel operation tops, seamless welding with round cornerwhich is anti-corrosion and easy to clean Stainless steel shelf & rack, 4 or 6 pcs shelves optional, shelf removable and spacing height adjustable Stainless steel pre-cooling rack with metal cover Integrally molded glass dried barrel adopted special plastic will not break Used SECOP (DANFOSS) quality compressor, high performance condenser fan, LCD touch display, history data can be stored, searched and exported to computer. Model R TP MR MTP MT Image Description Normal type Stoppering Manifold Stoppering + Manifold Multi-ports manifold Freeze Dryer Transparent dry chamber Vacuum pump Stoppering device Manifold Ports 8 ports (28/ 32mm) 8 ports (28/ 32mm) 24 ports Freezing rack Drying rack Tray 4 pcs 3 pcs 4 pcs 3 pcs FD-10S, FD-12S, FD-18S Series Shelf heating & program controlling (optional) Electric heating element for each shelf, Auto + Manual operation; 36 Segment programs can be set used for kind of different raw material Temperature sensor ensure to monitor temperature of each shelf Data can be export to computer for analysis 7 LCD touch display, easy to operate on machine Real-time alarm display and historical alarm query function to facilitate fault diagnosis and equipment maintenance. Users can set the level and password, decentralized operation and management. Sensor calibration to ensure long-term accuracy of the measured value www.labfreez.com ~ 6 ~
FDSERIESLab Freeze Dryer/Lyophilizer Optional items Item No. Item Name Item No. Item Name FD1001-80 C Condenser FD10091000 1000ml flask Fd1002 Defrost device FD1010 Eutectic point test device FD1003 Refrigerant R404a, R502, R23 and etc FD1011 Vacuum regular device FD1004 Oil mist filter FD1012 Jar bottle FD1005 Shelv es heating & Program segment control Can stored 16 programs, each program can be set up FD1013 Change to SS316 condenser & shelv es 36segments, correct program data in computing, memorize the drying curve FD1006 6pcs shelves instead of 4 pcs FD1014 Capacitance type vacuum gauge FD1007 Leybold vacuum pump FD1015 Backfill filter FD1008 Anti-back oil device FD1016 Auto backfill / drainage system FD1009100 100ml flask FD1009250 250ml flask FD1009500 500ml flask Vacuum Pump for FD series freeze dryer Adapter Quick-release pipe Small-bore pipe Oil mist collector Specifications of vacuum pump Model 2XZ-0.5 2XZ-1 2XZ-2C 2XZ-4C 2XZ-6C 2XZ-8C 2XZ-15C Pumping Speed: L/S 0.5 1 2 4 6 8 15 U lt. Without gas ballast 6 10-2 Vacuum Pa With gas ballast 6.5 1.33 Speed: r/min(50h Z) 1400 Power Required: Kw 0.18 0.25 0.37 0.55 0.75 1.1 1.5 Diameter of inlet port: mm 16 16 25 25 40 40 40 Temp. rise of pump oil: C 40 45 45 65 70 Oil capacity : L 0.60 0.70 0.10 1.2 2.0 3.0 4.0 www.labfreez.com ~ 7 ~
FDSERIESLab Freeze Dryer/Lyophilizer Overall Dimensions: mm 447 168 260 469 168 260 514 168 282 514 168 282 565 200 342 650 240 430 770 240 430 Weight: kg 16 17 20 22 40 60 75 www.labfreez.com ~ 8 ~
LABSERIES Standard Freeze Dryer/Lyophilizer LAB-Series LabFreeze Dryer (Lyophilizer) Features Touch LCD display with microprocessor controller, easy to use. Dry chamber using aircraft grade acrylic materials, non-adhesive, high strength, and no leaks. C ondenser pre-cooling function. Used DANFOSS compressor. Vacuum pump in Japan or Korea brand, w ith oil-mist filter can trapping oil mist in the ex haus t gas, reduce environmental and health hazards. Can charge nitrogen or inert gas to save after drying. Programmable, freezing, drying and defrosting will be program controlled. Automatic control sy stem: Temperature heating control for each shelv es, heating circulation monitoring protect, fuzzy PID control algorithm. Defrost system: Auto Non-electric heating defrost, more safety and fast. Vacuum regular sy stem: v acuum degree regular in sublimation and dry ing process to av oid special material foaming or blowing, accelerate lyophilized efficiency (Optional) Pulse backfill sy stem: slow, medium, fast three kinds of backfilling mode selection, av oiding the granular material and flocculent material being blown out effective loss problem inflatable pro duce. (Optional) Automatic drainage sy stem: interlock w ith v acuum sy stem after draining to prev ent any failure in vacuum system. (Optional) C an be w ork in automatic or manual operation, manual mode is used to ex plore the proces s parameters, automatic mode for process maturity. Data recording sy stem: 1) data can be stored in machine in 3 months; 2) Ex ternal U-disk storage (Optional); 3) PC-database storage (Optional) Monitoring sy stem: real time sy stem temperature and v acuum degree monitored, acquisition frequency 50ms / time. Ly ophilization process recipe storage function: can store 500 set of fix ed or user-defined ly ophilized formulation process. PC remote monitor sy stem: remote monitor w orking status of machine, max 1.5km distance (Optional) Eutectic point test function (Optional) C alibration function: temperature and v acuum calibration ensures long-term accuracy of the measured v alues. Freeze-drying curve searchable. Freeze dryer with manifold & stoppering system Safety Protection Over-current protection Over-load protection Over-heating of temperature Vacuum defense in processing 36V safety voltage for heating system Vacuum pump protection Freeze dryer with -80 C condenser Configuration Instruction www.labfreez.com ~ 9 ~
LABSERIES Standard Freeze Dryer/Lyophilizer N ormal ty pe(r): suitable for bulk material Stoppering ty pe(s): suitable for sealing vials material Flask-mount ty pe(f): suitable for external flask material Stoppering w ith flask-mount ty pe(fs): suitable for bulk, ex ternal flask and v ials material T-manifold ty pe(t): Suitable for external vials or flasks material -80 C condenser type Specifications Model LAB-1R-50 LAB-1R-80 LAB-1S-50 LAB-1S-80 LAB-1F-50 LAB-1F-80 LAB-1FS-50 LAB-1FS-80 LAB-1T-50 LAB-1T-80 Type N ormal Stoppering Flask-manifold Stoppering & Flaskmanifold T-manifold Control Programmed Programmed Programmed Programmed Programmed Display LCD touch LCD touch LCD touch LCD touch LCD touch Condenser temperature -55 C -85 C -55 C -85 C -55 C -85 C -55 C -85 C -55 C -85 C Water/ice capture 3L 4L 3L 4L 3L 4L 3L 4L 3L 4L Compressor power 7/8H P 2/3H P * 2 7/8H P 2/3H P * 2 7/8H P 2/3H P * 2 7/8H P 2/3H P * 2 7/8H P 2/3H P * 2 Defrost Yes Yes Yes Yes Yes Dry area (m 2 ) 0.12 0.08 0.12 0.08 - Shelf 4 pcs 3 pcs 4 pcs 3 pcs - Vacuum < 8 Pa < 8 Pa < 8 Pa < 8 Pa < 8 Pa Power 900W 900W 900W 900W 900W 1400W 1400W 1400W 1400W 1400W Voltage 220/50 220/50 220/50 220/50 220/50 110/60 110/60 110/60 110/60 110/60 www.labfreez.com ~ 10 ~
LABSERIES Standard Freeze Dryer/Lyophilizer Dimensions 470*600*400 470*600*400 470*600*400 470*600*400 470*600*400 (W*D*H)mm 640*640*1000 640*640*1000 640*640*1000 640*640*1000 640*640*1000 Optional Item ref. Item name Item ref. Item name LAB10001 Vacuum regular system, Vacuum trimming needle LAB10024 Paperless recorder, with USB interface * 1 + v acuum solenoid valve +1 LAB10002 Eutectic point tester (economic ty pe), measuring LAB10025 Remote controlling & monitoring system, RS485 temperature & resistance v alue LAB10003 Eutectic point tester (standard), measuring LAB10026 Anti-back oil solenoid v alve, SEGV brand temperature & resistance v alue online & offline, w ith softw are LAB10004 T ty pe 16 port manifold LAB10027 6 shelv es with tray dry chamber LAB10005 T ty pe 24 port manifold LAB10028 8 shelv es with tray dry chamber LAB10006 T ty pe 52 port manifold LAB10029 4 shelv es with trays, 12 port manifold-flasks LAB10007 T ty pe 104 port manifold LAB10030 6 shelv es with trays, 12 port manifold-flasks LAB10008 Ampoules sealer, sealing torch with tank LAB10031 8 shelv es with trays, 12 port manifold-flasks LAB10009 Vial capper, suitable for 12~30mm LAB10032 3 shelv es with trays, 12 port manifold-flasks with stoppering dev ice LAB10010 Jars adapter (Wide neck) LAB10033 Auto w ater drain dev ice, include solenoid valve, drain pipe & interface LAB10011 Pulse backfill system, Backfill solenoid valve *1+ pipe and adapter LAB10034 Mini dot matrix printer LAB10012 Backfill filter, 0.2u filter LAB10035 Oil mist filter, SEGV LAB10013 Backfill interface, USA APG, 8mm LAB10036 Oil mist filter, BWVAC LAB10014 PC-database storing system LAB10037 Oil mist filter, ULVAC LAB10015 U-disk data recording system, for online/offline LAB10038 Oil mist filter, Ley bold analy sis LAB10016 BWVAC Vacuum pump 1.5L/S LAB10039 ULVAC Vacuum pump 1L/S LAB10017 BWVAC Vacuum pump 3L/S LAB10040 ULVAC Vacuum pump 2L/S LAB10018 BWVAC Vacuum pump 6L/S LAB10041 ULVAC Vacuum pump 4L/S LAB10019 BWVAC Vacuum pump 8L/S LAB10042 Sample temperature monitor, display range -50~100 C LAB10020 LAB10021 LAB10022 LAB10023 Ley bold Vacuum pump 2L/S Ley bold Vacuum pump 4L/S Ley bold Vacuum pump 6L/S Ley bold Vacuum pump 8L/S Built-in freezing container Ampoules sealer Oil-mist filter 6~8 shelves with dry chamber www.labfreez.com ~ 11 ~
LABSERIES Standard Freeze Dryer/Lyophilizer Ley bold 6~8 shelv es w ith dry chamber Eutectic point tester Vial capper vacuum pump and flaks mount T- 16/24/52/104 manifold Jars adapter Oil anti-back system Backfill filter www.labfreez.com ~ 12 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer FD Series Pilot scale automaticfreeze dryer Features: Chamber Rectangular type dry chamber, Pre-freezing, drying in same chamber without any manual operation. Drying chamber & shelves made by polished SS 304 or material contact parts SS316 is optional, adopted high strength, high transmittance plexiglass door, easy to observe, inside round corner, easy to clean. Oil circulation heating type with high temperature precision control, usually suitable for medical, bio field, electric heating type suitable for food field. GUNDFOS shielded circulating pump and PID control electric heating component; circulation liquid used Low-temperature lowviscosity silicone oil. Shelves heating system uses safe voltage, while heating rate controllable. (Electric heating type) Condenser (cold trap) M ade by SS304 drum-type cold trap, with high transmittance plexiglass door, Integrity or separately condenser and chamber can be chosen. Patented gas diversion technology, cold trapping ice even, ice-catching ability. Refrigeration Dual-stage cooling, famous hermetic compressor which is low noise, capillary throttling technology, air-cooled or water-cooled is available. Brazed plate heat exchanger. Environmental-friendly refrigerant. Control Flexible manual + automatic control, manual groping process, automatic batch production. PLC control with 7 LCD touch graphic display, can be operated in auto, semi-auto and manual mode. Shelf temperature adjustable, controllable, explore suitable for pilot and production processes. www.labfreez.com ~ 13 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer 32 programs, each program can be set as 36 segments, curve can be stored, processing parameters can be modified in real time. Built with recorder, with USB interface data can be exported to computer for analysis, FD-LYO software & computer is optional for controlling by remote way. sensor calibration function, to ensure long-term use of the accuracy of the measured value. Real-time alarm display and historical alarm inquiry function, convenient fault diagnosis and equipment maintenance. Users can set the level and password, decentralized operation and management. Vacuum Two-stage rotary vane vacuum pump, vacuum is automatic adjust and can be set (optional). Ultimate vacuum can reach 5 Pa, in order to reach highest vacuum, Leybold brand vacuum pump is optional. Others Normal type suitable for bulk raw products like food, fruit, herbal medicine and bio material. Stoppering type suitable for vials comes with cap, to stoppering caps into the vials. Inflatable (water) valve with a safety diaphragm valve can be connected to the inert gas source, dry and filled with inert gas, to extend the shelf life of the material. CE/ISO 9001 13485 14001 certificated. Can be conforms to GM P standard. Main characteristics: FD-10F Series FD-10F Series FD-10F-R (Silicon oil heating) FD-10F-TP (Silicon oil heating) M odel FD-10-RE (Electric heating) FD-10F-TPE (Electric heating) Specification Normal With stoppering Picture Shelf area 0.2 m Drying 2 0.1 m 2 Shelf quantity 2 pcs 1pc chamber Shelf temp. range -70 C ~ +65 C www.labfreez.com ~ 14 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer Condenser Vacuum Basic parameters -50 C ~ 70 C Shelf space height 70mm Shelf dimension 400 270mm Ф22mmvials(piece) 440 220 Ф16mm vials (piece) 868 434 Ф12mmvials (piece) 1554 777 Tray dimensions 395 265mm 395 265mm Tray quantity 2 1 Sample loaded capacity 2L 1L Stoppering device No Yes Material SS304 (chamber, shelves, trays) M ax temp. -80 C -60 C (-80 C is optional) Ice capture capacity 6Kg/24hs Defrost Natural (Electric heating is optional) M aterial SS304 Vacuum pump Included Vacuum rate 4L/S Vacuum degree 5 Pa Style of cooling Air-cooled Dimension(L*W*H) 655 640 1200mm 655 640 1200mm Weight 210kg 210kg Control method PLC auto + manual Installation power 2Kw Voltage 220V/50Hz (can be change to 110V/60Hz) FD-20F Series FD-20F Series M odel FD-20F-R FD-20F-TP Specification Regular Top-press Pictures Freeze-drying area 0.3 m 2 0.2 m 2 Heating method Circulation oil heating Circulation oil heating Shelves quantity 3 pcs 2+1 pcs Shelves temp. range -50 C ~70 C -50 C ~70 C Drying chamber Temp. difference 1 C 1 C Shelves space 70mm 70mm Dimensions of shelves 400*270 mm 400*270 mm Size of tray 395 265mm * 3 pcs 395 265mm * 2 pcs Ф22 Bottle (piece) 440 440 www.labfreez.com ~ 15 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer Cold trap Basic parameters Ф16Bottle (piece) 868 868 Ф12 Bottle (piece) 1554 1554 Sample loaded capacity 3L 3L Stoppering device No Yes Material SS304 (chamber, shelves, trays) SS304 (chamber, shelves, trays) Cold trap temperature -75 C -75 C Water-capture capability 6 Kg/24h 6 Kg/24h M aterial SS304 SS304 Ultimate Vacuum 5 Pa 5 Pa Pump rate 4L/s 4L/s Style of cooling Air Cooling room temperature 25 C Air Cooling room temperature 25 C Power supply 220V/50Hz or 110V/60Hz 220V/50Hz or 110V/60Hz Power 3000W 3000W Weight 300kg 310kg Dimension 770x750x1520 mm 770x750x1650 mm Control method PLC auto + manual PLC auto + manual FD-30F Series FD-30F Series M odel FD-30F-RE FD-30F-R FD-30F-TP Silicon oil circulation Silicon oil circulation Heating type Electric heating heating heating Drying chamber Vial load capacity (pcs) Cold trap Picture Freeze-drying area 0.4 m2 0.4 m2 0.306 m2 Shelf quantity 4+1 pcs 4+1 pcs 3+1 pcs Shelf temp. range -50 ~ 70 C -50 ~ 70 C -50~70 C Temp. Difference +/-1 C (balance) +/-1 C (balance) +/-1 C (balance) Shelf size 300 340mm 300 340mm 300 340mm Sample loaded capacity 4L 4L 3L Shelf spacing 50mm 50mm 70mm Tray size 295 335mm 295 335mm 295 335mm Tray quantity 4 pcs 4 pcs 3 pcs M aterial of chamber Polish SS304 Polish SS304 Polish SS304 M aterial of Shelves Polish SS304 Polish SS304 Polish SS304 M aterial of trays SS304 SS304 SS304 Ф22 vials 728 728 546 Ф16 vials 1440 1440 1080 Ф12vials 2600 2600 1950 Cold trap temperature -60 C -75 C -75 C Ice capture capability 8 Kg/24h 8 Kg/24h 8 Kg/24h Defrost Nature Nature Electric or hot gas www.labfreez.com ~ 16 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer Basic parameters Control method Cold type Air-cooled Air-cooled Air-cooled M aterial SS304 SS304 SS304 Style of top-press - - Hydraulic pressure Ultimate vacuum 5 Pa 5 Pa 5 Pa Vacuum rate 6L/S 6L/S 6L/S Dimension (mm) 890 660 1210 920 780 1350 1280*900*1630 Weight 280 kg 400 kg 450 kg Voltage Freeze dryer 220V/50Hz 220V/50Hz 220V/50Hz 110V/60HZ 110V/60HZ 110V/60HZ Power 2700W 4500W 5500W PLC auto + manual FD-50F Series FD-50F Series M odel FD-50F-RE FD-50F-R FD-50F-TP Heating type Electric heating Silicone oil circulation Silicone oil circulation Picture Drying chamber Freeze-drying area 0.6 m 2 0.7 m 2 0.5 m 2 Shelf quantity 6 pcs 4+1 pcs 3+1 pcs Shelf temp. range -50 C ~70 C -50 C ~70 C -50~70 C Temp. Difference +/-1 C (balance) +/-1 C (balance) +/-1 C (balance) Shelf size 300 340mm 480 360mm 410 410mm Shelf spacing 50mm 50mm 70mm Sample load capacity 6L 7L 5L Tray quantity 6 pcs 4 pcs 3 pcs Tray size 295 335mm 475 355mm 405 405mm M aterial of chamber Polish SS304 Polish SS304 Polish SS304 M aterial of Shelves Polish SS304 Polish SS304 Polish SS304 M aterial of trays SS304 SS304 SS304 Vial load capacity Ф22 vials (piece) 1408 1408 1050 Ф16 vials (piece) 2728 2728 2058 Ф12vials (piece) 4920 4920 3705 Cold trap Cold trap temperature -60 C -75 C -75 C Ice capture capability 10 Kg/24h 10 Kg/24h 10 Kg/24h Electric defrost Nature Nature Electric or hot gas Cool type Air cooled Air cooled Air cooled M aterial SS304 SS304 SS304 Basic parameters Style of top-press - - Hydraulic pressure Ultimate vacuum 5Pa 5Pa 5Pa Vacuum pump Included Included Included Pump rate 8L/S 8L/S 8L/S www.labfreez.com ~ 17 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer Dimension (mm) 890 670 1410 1000 785 1420 1490 850 1620+240 Weight 450kg 600kg 800 kg Voltage Freeze dryer 380V±10%50Hz/60Hz 380V±10%50Hz/60Hz 380V±10%50Hz/60Hz Power 4500W 5500W 6500W FD-100F Series FD-100F Series M odel FD-100F-R FD-100F-TP Heating type Silicone oil circulation Silicone oil circulation Picture Drying chamber Vials load capacity Cold trap Basic parameters Control method Drying area 1.0 m2 1.15 m2 Shelf quantity 6+1 layer 4+1 layer Shelf Temp range -50 C ~70 C -50~70 C Shelf temp. difference ±1 C (balance) ±1 C (balance) Shelves size 480*360mm 480 600mm Tray size 475 355mm 475 595mm Tray quantity 6 pcs 4 pcs Raw material loaded capacity 10L 11L Height space 70mm 70mm M aterial of chamber Polish SS304 Polish SS304 M aterial of Shelves Polish SS304 Polish SS304 M aterial of trays SS304 SS304 Ф22 vials (PCS) 2112 2460 Ф16 vials(pcs) 4092 4788 Ф12vials (PCS) 7920 8624 Condenser temp. -75 C -70 C Condenser capability 15 Kg/24h 15 Kg/24h Defrost Electric heating Electric heating M aterial SS304 SS304 Vacuum pump Included Included Ultimate Vacuum 5 Pa 5 Pa Pump rate 15L/S 15L/S Style of top-press - Hydraulic pressure Cooling type Air cooled Air cooled Dimension (mm) 1170 830 1665 1640 1100 1630+350 Voltage 3p-380~400V/50Hz 3p-380~400V/50Hz Install Power 6500W 7500W Weight 700kg 1000kg PLC auto + manual FD-200F Series www.labfreez.com ~ 18 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer FD-200F Series Model FD-200F-R FD-200F-TP Heating ty pe Silicone oil circulation Silicone oil circulation Picture Dry ing chamber Vials load capacity C ondenser Basic parameters Refrigeration unit Freeze-dry ing area 2.25 m 2 1.98 m 2 Shelves quantity 5+1pcs 4+1pcs Shelf Temperature -50 C ~70 C -50 C ~70 C Shelf Temp. Accuracy ± 1 C ± 1 C Shelf spacing 80~100mm 80~100mm Size of shelves 500*900*20 mm 610*810*20 mm Raw material load capacity (be better) 22L 20L Material of chamber Polish SS304 Polish SS304 Material of Shelves Polish SS304 Polish SS304 Material of trays SS304 SS304 Ф22 vials (PCS) 4100 3600 Ф16 vials (PCS) 7800 6800 Ф12 vials (PCS) 14400 12600 Max temperature -75 C -75 C Water-capture capability 40 Kg/24h 40 Kg/24h Defrost water soaking water soaking Material SS304 or SS316 SS304 or SS316 Vacuum degree 5 Pa 5 Pa (Range:1~300Pa) Dimension 1200*2100*1700 (mm) 1300*3300*2500 (mm) Max Power 13.5kw 15kw Weight 2300 kg 2600 kg Data Process RS232 Interface or USB Control method PLC auto + manual Compressor Bitzer or TECUMSEH, 2 set Pow er 7 Kw Refrigerant R507 & R23 Cooling type Air cooled Pressure controller DANFOSS Expansion valve DANFOSS Optional items for FD Pilot type Item No. Item Name FDF1001 FDF1002 FDF1003 FDF1004 Stainless steel shell (SS304 or SS316) Rotary Device Control software PC FDF1005 Eutectic point tester www.labfreez.com ~ 19 ~
FDSERIES Pilot Freeze Dryer/Lyophilizer FDF1006 FDF1007 Leybold vacuum pump Defrost device (for special model) FDF1008 FDF1009 FDF1010 FDF1011 FDF1012 Air compressor (for Pneumatic door opening) Vacuum pump solenoid valve External material change to SS304 Condenser, trays, shelves change to SS316 6 port manifold system (extra port customizable) FDF1013 FDF1014 FDF1015 FDF1016 Data logger Backfill filter Capacitance type vacuum gauge Vacuum regulation system www.labfreez.com ~ 20 ~
FD-P SERIESProcess Freeze Dryer/Lyophilizer FD-P Series Process Freeze Dryer For medicine use Main Functions Shelf pre-freezing function. Can be filled with nitrogen or inert protect machine after working. lyophilized automatic control system: procedural programming, both freezedried and defrost control procedures. Shelf: adopting international advanced welding technology without leak (threeyear warranty). Lyophilized end point test system: automatic lyophilized end testing parsed end of the drying stage, to ensure that the moisture content of the material to reach the standards. Vacuum regulator systems: sublimation and vacuum drying process analytical adjustment, avoid special material to foaming & blowing, accelerate lyophilization efficiency. 1~5 m 2 Pulse backfill system: slow, medium, fast three backfill mode selection, avoiding the issue for the end of the freeze-dried granular material and flocculent inflatable produce effective substances are blown away loss. Large industrial touch screen, human-computer interaction is good, easy to understand, no instructions are also available for easy operation. Monitoring system: real-time monitoring system temperature, vacuum, acquisition frequency 50ms / times. Lyophilization process recipe storage function: can store 2000 group fixed or user-defined lyophilized formulation process. PC remote monitoring system: remote monitoring equipment operating conditions, as far as monitoring distance 1.5KM. Eutectic point test function (optional). Process data recording system (optional). Calibration function: temperature and vacuum calibration ensures long-term accuracy of the measured values. Lyophilized curve inquiry function (available temperature and vacuum degree curve, convenient process optimization and lyophilized effect verification). Features Cabinet: Cabinet design according to GB150-2011 / PED ASME standards, in line with FDA and GMP standards. Internal cabinet with large rounded design, with mirror polished surface, bottom of the box with tilt design, also i n line with CIP and SIP drainage requirements. It can withstand: 0.15Mpa to 0.5Pa full range of positive and negative pressure. www.labfreez.com ~ 21 ~
FD-P SERIESProcess Freeze Dryer/Lyophilizer Shelf: adopts international advanced welding process. Internal welding, TIG welding and orbital welding technology Condenser: with polishing technology, surface bright and smooth. Water vapor channel optimized design to ensure small molecule surge resistance, more efficient water capture. Refrigeration system uses world famous refrigeration compressors, refrigeration system security and stability. Vacuum system: vacuum pipe with automatic orbital welding, ensure welding firm appearance. Using helium vacuum leak detector testing to ensure vacuum system to achieve high vacuum requirements. CIP system CIP system valves and pneumatic actua tors are imported original, to ensure stable operation, safe and reliable. CIP system piping with automatic orbital welding, ensure welding firm appearance. CIP vacuum system piping using helium leak detector testing to ensure vacuum system to achieve high vacuum requirements. water pump imported from Germany to remove residual moisture after cleaning, cleared completely. SIP system uses a pulsating pre-vacuum steam sterilization, with Fo value display and recording, with complete safety interlock and interlock functions, box comes with a cooling function. Triple overpressure protection, to ensure absolute safety. Case high pressure vessel design, manufacturing process, all components of industrial X-ray machine detected by testing, ensure that the overall firm, resistant to high pressure. Valves are used in place disinfection system temperature up to above 350 C of the original imports. Pneumatic actuators are imported original, ensure stable operation, safe and reliable. Reign disinfection system with automatic orbital pipe welding, welding to ensure strong and beautiful. SIP system piping using helium vacuum leak detector testing to ensure vacuum system to achieve high vacuum requirements. Remove residual moisture after sterilization imported from Germany, water ring pumps, pumping speed, completely clear. Maximum sterilization temperature up to 150 C. Process Control System, meet FDA 21 CFR PART 11 electronic records, electronic signatures cannot be modified requirements. Precisely controlled, repeatable, can be restored. Plate heat exchanger, using the world-class plate heat exchanger, heat transfer efficiency. SIP type suitable for the use of the pharmaceutical sector. CIP type suitable for use in the field of biological engineering. Common type suitable for industrial, food and other fields use Safety: Independent Overcurrent protection for various facilities Independent overload protection for various facilities Conditions allow individual facilities operating Heating overtemperature protection Product vacuum freeze-drying process protection www.labfreez.com ~ 22 ~
FD-P SERIESProcess Freeze Dryer/Lyophilizer Vacuum pump protection System logic interlock Meet the GMP standard Model Shelf area ( m2 ) Shelf qty Shelf size (mm) Temp. accuracy( C) Condenser Vials load water capacity ( 22) (L) Shelf Condenser temp. ( C) temp. ( C) Power (KW) FD-P1 1.08 4+1 450*600 ±1.0 20 2100-60-80 <-85 9 FD-P2 2.19 4+1 600*900 40 4200 12 FD-P3 3.24 6+1 600*900 60 6300 21 FD-P5 4.86 6+1 900*900 100 9450 24 FD-P7 7.56 7+1 900*1200 150 15750 44 FD-P10 9.72 9+1 900*1200 200 19950 58 FD-P13 12.96 9+1 1200*1200 260 26250 67 FD-P15 16.1 9+1 1200*1490 320 33600 75 FD-P20 19.67 11+1 1200*1490 400 42900 104 FD-P25 25.0 14+1 1200*1490 500 52500 125 FD-P30 31.5 14+1 1490*1490 600 60900 134 FD-P40 42 14+1 1490*1990 800 84000 174 FD-P50 51.0 17+1 1490*1990 1000 105000 210 15 m 2 20m 2 25m 2 40m 2 www.labfreez.com ~ 23 ~
FD-FP SERIES Process Freeze Dryer/Lyophilizer FD-FP Series Vacuum Freeze Dryer(Lyophilizer) For food processing Main application of food freeze dryer: Vacuum freezing and drying technology is currently the most advanced technology for food dehydration processing in the world. Compared with the common ly used drying method, the freeze-dried food produced with this technology features long period of quality assurance, good re-hydration nature, good-looking color, good flavor, taste and high content of nutritious components. The dried food basically remains unchanged in its volume and shape, looks like sponge and has no shrinking. This drying technology can be widely used in process of vegetables, fruits, condiments, aquatic products, biological products, medicine, beverage, exemplar etc. Main part of food freeze dryer: FD-FP series vacuum cryogenic drying equipment mainly includes food pre-freezing system, drying bin system, heating system, vacuum system, refrigerating system, material conveying system, medium system, pneumatic system, cleaning and sterilizing system. Main technical parameters of food freeze dryer: Model FD-FP1 FD-FP5 FD-FP10 FD-FP20 FD-FP30 FD-FP40 FD-FP60 FD-FP75 FD-FP90 FD-FP100 Shelf area (m 2 ) 1 5.5 11.4 22.4 35.6 45.6 59.28 74.88 89.8 100 Chamber size (mm) Diameter Φ600 Φ1200 Φ2300 Φ2300 Φ2300 Φ2400 Φ2500 Φ2500 Φ2500 Depth 700 1480 1300 2250 3300 4300 3170 4200 5200 Shelf quantity (pcs) 4+1 8+1 10+1 10+1 10+1 10+1 13+1 13+1 13+1 Shelf size (mm) W 400 360 600 600 600 600 600 600 600 D 625 1000 950 1900 2850 3800 3800 4800 5800 H 20 20 15 15 15 15 15 15 15 Shelf height space (mm) 60 60 80 80 80 80 80 80 80 Carts quantity (pcs) 0 1 1 2 3 4 4 5 6 Tray size (mm) W 395 330 460 460 460 460 460 460 460 D 625 350 640 640 640 640 640 640 640 H 30 20 40 40 40 40 40 40 40 Tray quantity 4 48 40 80 120 160 208 260 312 www.labfreez.com ~ 24 ~
FD-FP SERIES Process Freeze Dryer/Lyophilizer Heating medium Silicone oil Temp. range ( ) RT -120 Ice capture capacity (KG) 20 100 200 400 600 800 1000 1500 2000 Condenser temp. ( ) -50 or -70 Condenser cooling method Direct evaporation Def rost type Hot water spray Def rost water capacity (Kg) 230 1000 200 400 600 800 1000 1500 2000 Ultimate vacuum (Pa) 10Pa 10Pa 10Pa 10Pa 10Pa 10Pa 10Pa 10Pa 10Pa Install power (KW) 6.5 12 24 46 70 85 110 160 200 Cooling ty pe Air cooled Water cooled Cooling water (T/H) / 8 20 30 40 50 60 80 100 Cooling water pipe diameter (mm) / DN40 DN50 DN50 DN65 DN65 DN65 DN65 DN80 W 2010 2500 4000 6000 9000 9000 9000 1300 16000 Dimensions (mm) L 1300 1400 2100 2100 2100 2400 2900 2900 2900 H 1720 1600 2300 2300 2300 2600 3200 3200 3600 Weight (T) 1 4.8 8.6 17.5 26 32 40 40 80 www.labfreez.com ~ 25 ~