Using Technology to Address the Security Challenges of Today and Tomorrow

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CNS Partnership Conference Pauline E. Leary, Ph.D, Jennifer Banks Hermann, Espy Martinez, Chris Steinmann May 6-8, 2018 Palm Springs, California Using Technology to Address the Security Challenges of Today and Tomorrow

Smiths Group Smiths Detection is one of five operating divisions of Smiths Group, a global technology company listed on the London Stock Exchange. Employing over 23,000 people in more than 50 countries, Smiths Group is a world leader in the practical application of advanced technologies, delivering products and services for the threat and contraband detection, medical devices, energy and communications markets worldwide. 2

Smiths Detection Smiths Detection is a global leader in threat detection and screening technologies for aviation, ports and borders, urban security and the military. With more than 40 years of field-tested experience, we deliver the solutions needed to protect society from the threat and illegal passage of explosives, prohibited weapons, contraband, toxic chemicals and narcotics 3

Modern threats Explosives and explosive devices Chemical threats People passengers and employees Vulnerabilities at facilities and borders Evolving opportunities 4 Smiths Detection: an introduction

Addressing these threats Technologies that work Technologies that are deployable Meet the immediate security requirements Adaptable Range of detection and detection-limit capabilities Complementary rather than redundant capabilities 5

Exceptional capability through technology Explosives and explosive devices White-powder threats Chemical threats, including drugs, opioids and fentanyls Chemical warfare agents Concealed contraband 6

Exceptional capability through technology Technologies X ray imaging Computed Tomography (CT) Millimetre-wave imaging Automated Threat Recognition algorithms (ATRs ) Ion Mobility Spectrometry (IMS) Gas Chromatography/Mass Spectrometry (GC/MS) Fourier- Transform Infrared (FTiR) Raman spectroscopy Gamma ray spectroscopy Detection and Identification Imaging: Conventional X-ray Systems Explosive Detection Systems Cargo Inspection Systems Integrated systems Sensing: Toxic chemicals Explosives, radiation, chemical warfare agents and narcotics We have more technologies in more sectors, in more countries, than any other detection company 7

X-ray imaging Multiple Options to Improve Detection Generator Geometry Single view Double view Algorithm development Software interfaces Ease of use 8

X-ray imaging 9

Co Computed tomography High-speed explosives detection 10

Computed tomography High-speed explosives detection 11

Computed tomography Checkpoint of the future High-speed explosives detection 12

Spectroscopic analysis for conclusive ID 13

Spectroscopic analysis for conclusive ID 14

Mass spectrometry for conclusive ID 15

Mass spectrometry for sample sourcing C4 with 0.1% DMNB 16

Ion mobility for detection of residues Ceramic drift tube & reaction region High temp capabilities, with low self contamination at higher temps Switching-polarity capability Lowers costs significantly Hot drift tube Can get more chemicals into the vapor phase Use of on demand vapor generators (OVG) Singe use swab with tacky coating Very effective pickup of residues Hygienic 17

Adaptation (to fentanyls) 18

Value of fentanyl First synthesized by Paul Janssen in 1960, and marketed initially by IV Solved problems with morphine-oxygen anesthesia, including incomplete amnesia, occasional histaminerelated reactions, and marked increases in intra- and postoperative respiratory depression Fentanyl citrate lollipops for cancer patients and soldiers on the battlefield Patches and other forms for chronic pain Fentanyl is 100-times more potent than morphine Carfentanyl, 10,000-times the potency of morphine, used by veterinarians to immobilize some large animals 19

Scourge of fentanyl from the headlines 20

Safety concern Fentanyl may be absorbed through the skin (no smoking, snorting, injecting, etc., required) Inadvertently inhaled when particle samples become airborne LD 50 (lethal dose) for pure fentanyl, is estimated at 2 milligrams (mgs) for a typical adult Different forms (analogues) of fentanyl that are even more deadly than pure fentanyl Acetylfentanyl 3 x H Butyrylfentanyl 3 X H Furanylfentanyl 4 x H Fentanyl 20 x H Methylfentanyl 100 x H Carfentanyl 2000 x H W-18 2000 x H 21

Lethal dose of fentanyl https://www.fentanylsafety.com/ https://www.statnews.com/2016/09/29/fentanyl-heroin-photo-fatal-doses/ 22

Identification with conclusive identification and interpretation support 365/24/7 23

Keeping passengers and infrastructure safe Checkpoint integrated solution Hold baggage integrated solution Smiths Detection s technology solutions for hold baggage screening and checkpoints meet the most stringent regulatory standards and highest requested detection rates. 24

Summary Scientifically sound instruments that perform well Technology that s deployable Meet the security requirements of the end user Technology and methods that are adaptable Range of detection and detection-limit capabilities Complementary capabilities 25

Pauline Leary Pauline.Leary@smiths-detection.com Jen Banks Hermann Jennifer.Banks.Herrmann@smiths-detection.com Espy Martinez espy.martinez@smiths-detection.com Chris Steinmann chris.steinmann@smiths-detection.com 26