CGCM Regional Report Korea Presented by Yeong Shik Kim (kims@snu.ac.kr) Aug. 27, 2014, Beijing 1
SEOUL The 1 st Meeting : Feb. 2014 Members - Prof. Ho Cheol Kim (Department of Herbalogy, College of Korean Medicine, Kyunghee U - Prof. Yoon Jeong Kim (Deparment of Oriental Pharmacy, Wonkwang U) - Prof. Sik Jong Jin (Department of Herbal Medicne Resource, Cheonbuk National U) - Prof. Jong Hyun Lee (Department of Pharmacy, Dongduk Women s U) - Dr. Seryang Oh (Natural Medicine Research Center, Korea Research Institute of Bioscience & Biotechnology) - Prof. Yeong Shik Kim (Natural Products Research Inst, College of Pharmacy, Seoul National University) 2
Contact point : Dr. Se Ryang Oh seiryang@kribb.re.kr 3
Chonbuk National University CBNU Jeonju Main Campus Chonbuk National University World Class Research Competitiveness 1 st in Korea, Increase Rate of Published SCI Papers (2009 MEST) 1 st among national universities, Research Grants (2010~2012 three consecutive years) 4
Chonbuk National University National University Rankings (Joongang Daily Press) Chonbuk National University City of Tradition, Art and Delicacies Only 3 hours from Seoul Tradition: Hanok Maeul (Korean Folk Village) Art: Hanji (Traditional Korean Paper) Delicacies: Bibimbab and Hanjeongsik Contact point : Prof. Jong Sik Jin mistbcomdew@hanmail.net 5
SEOUL NATIONAL UNIVERSITY (SNU) 6
SEOUL NATIONAL UNIVERSITY (SNU) 7
SNU CAMPUS MAP We are here Natural Products Research Institute Seoul National University -WHO Collaborating Center for Traditional Medicine Natural product chemistry -UNESCO Regional Reserch Center for Chemistry of Natural Products in Southeast Asia -National Center for Standardzation Herbal Medicine (KFDA) Natural product resources Lead compounds Preclinicical res. Clinical res. Natural product informatics Biological activity 8
History of Institution 1939 1945 1950 1970 1980 1992 2008~ 1970~1979 1939~1945 On Dec. 27, 1939, NPRI was founded About 15,000 indigenous plant specimens collections 1945~1949 Built our own elemental analyzer for the first time in Korea 1950~1969 NMR spectrometer was first introduced Determination of acetannin and polygallitol structure Supported by WHO Headquarters of "Regional Network for the Chemistry of Natural Products in Southeast Asia" by UNESCO 1980~1989 WHO designated the Institute as a "WHO Collaborating Center for Traditional Medicine 1992~ Korea-China Collaboration Center for Traditional Oriental Medicines Research (1992) Completion of the Basic Technology and Research Building (1997) National Center for Research and Development of Natural Products (2001) National Center for Standardization of Herbal Medicines 2008 MOVE to Main Campus Director College of Pharmacy Faculty Meeting Committee on Research Evaluation Graduate Program in Natural Products Science Natural Products chemistry Natural Products Resources Biological Activity Research Industrial Technology Cooperation General Affairs Radioistope Laboratory Instrumental Analysis Center Economic Plants Research Station Experimental Animals Laboratory Natural Products Information Library 9
Standard Extracts /Fractions Structure Determination Natural Products Chemistry Systematic Botanical Identification Collection Cultivation Natural Products Resources Lead Compounds Preclinical Studies Clinical Studies Natural Products Informatics Natural Products Screenings Biological Activity Assay Tradimed DB Napralert DB Pubmed, CHCD Natural Products Chemistry Isolation, purification and structure determination of bioactive compounds Quality control of herbal drugs Total synthesis Natural Products Bank Biological Activity Research Biological activities(in vitro, in vivo) Studies on pharmacodynamics and metabolism Studies on toxicity and safety Target Diseases Anti-cancer and Anti-virus Cardiovascular system Anti-inflammatory Anti-thrombotic Anti-obesity Neuropharmacology Mental diseases Proteomics, Glycomics Neutraceuticals and Cosmoceuticals 10
Center for Drug Development Opening at July 2014 11