GL FILTRATION Ltd. World Leaders In Solid-Liquid Separation

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1 GL FILTRATION Ltd World Leaders In Solid-Liquid Separation

2 GL Filtration Limited Unit 11 Oakleaf Industrial Estate Bankwood Lane Rossington Doncaster South Yorkshire DN11 0PS United Kingdom Tel: Fax:

About GL Filtration Limited GL Filtration Limited specialise in the design and manufacture of Filtration and Drying equipment for the pharmaceutical and related industries.

3 About GL Filtration Limited GL Filtration Limited specialise in the design and manufacture of Filtration and Drying equipment for the pharmaceutical and related industries. The primary focus of the companies products is in R & D, Kilo Lab and Pilot Scale. GLF s product range includes Nutsch Filters, Filter Dryers and Pan Dryers. All the equipment is capable of being supplied with integrated containment solutions for handling high potency products and for general cgmp.

Design Computer software including CAD and Solid Works ensure that all mechanical design is performed in-house.

Engineering which encompasses the effective implimentations systems and procedures required to produce high quality

Portobello-RMF Engineering successfully achieved registration to the British and European Quality Standards ISO

4 Design Computer software including CAD and Solid Works ensure that all mechanical design is performed in-house. Quality A fully documented Quality System has been developed by our joint venture partners Portobello-RMF Engineering which encompasses the effective implimentations systems and procedures required to produce high quality products. Portobello-RMF Engineering successfully achieved registration to the British and European Quality Standards ISO 9001, EN 29001:1987 in 1992 and have since been successful in retaining this registration under the revised standards of BS EN ISO 9001:1994. ASME U Stamp. In 2004 Portobello-RMF Engineering successfully achieved accreditation to

R & D Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD80 80

018 5 2 FilterLab80 The FilterLab80 has been specifically designed to enable simulation of fill scale filter dryers.

5 Litre Cake Capacity Chamber Electrically Driven Variable Speed Agitator with Auto Dry Feature Hydraulic Raise/Lower of

specifically designed to enable simulation of full scale filter dryers.

5 R & D Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD or FD FD FilterLab80 The FilterLab80 has been specifically designed to enable simulation of fill scale filter dryers. The filter dryer incorporates: 2 Litre Slurry Capacity Chamber 0.5 Litre Cake Capacity Chamber Electrically Driven Variable Speed Agitator with Auto Dry Feature Hydraulic Raise/Lower of Agitator Nitrogen Purged Agitator Seal Heated Agitator FilterLab80 With Extras The FilterLab80 with extras has been specifically designed to enable simulation of full scale filter dryers. The filter dryer incorporates:- 2 Litre Slurry Capacity Chamber 0.5 Litre Cake Capacity Chamber Electrically Driven Variable Speed Agitator with Auto Dry Feature Hydraulic Raise/Lower of Agitator Heated Agitator Weight Scale Glass Filtrate Receiver Mixing Timer for Automated Dryer Mode 8 Channel Data Logger Output Direct to Microsoft Excel

6 R & D FilterLab100 The FilterLab100 has been specifically designed to enable simulation of full scale filter dryers. The filter dryer package incorporates: 2 Litre Slurry Capacity Chamber 1 Litre Cake Capacity Chamber Electrically Driven Variable Speed Agitator Manual Raise/Lower of Agitator Glass Filtrate Receiver Glass Condenser Huber Ministat CC1 for Filter Jacket Heating Huber Ministat CC1 for Condenser Cooling Vacuum Pump Weight Scale 8 Channel DataLogger for all process critical parameters FilterLab150 The FilterLab150 has been specifically designed to enable simulation of full scale filter dryers. The filter dryer package incorporates: 5 Litre Slurry Capacity Chamber 2 Litre Cake Capacity Chamber Electrically Driven Variable Speed Agitator Manual Raise/Lower of Agitator Glass Filtrate Receiver Glass Condenser Huber Ministat CC1 for Filter Jacket Heating Huber Ministat CC1 for Condenser Cooling Vacuum Pump Weight Scale 8 Channel DataLogger for all process critical parameters

KILOLAB Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD200 200 0.

16 100 30 KiloLab200 The FD200 KiloLab Scale Filter has been specifically designed to enable fully contained processing of active

The KiloLab incorporates: 10 Litre Slurry Capacity 4 Litre Cake Capacity Electrically Driven Variable Speed Agitator Hydraulic Raise/Lower of

Scale Filter with Flexible Glovebag has been specifically designed to enable fully contained processing of active The KiloLab incorporates: 15

7 KILOLAB Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD FD or 25 6 FD FD FD FD KiloLab200 The FD200 KiloLab Scale Filter has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The KiloLab incorporates: 10 Litre Slurry Capacity 4 Litre Cake Capacity Electrically Driven Variable Speed Agitator Hydraulic Raise/Lower of Agitator Dry Running Mechanical Seal Heated Agitator Auto-Dry Feature Hazardous Area Electrics Available KiloLab200 - Glovebag The FD200 KiloLab Scale Filter with Flexible Glovebag has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The KiloLab incorporates: 15 Litre Slurry Capacity 6 Litre Cake Capacity Variable Speed Agitator Hydraulic Raise/Lower of Agitator Dry Running Mechanical Seal Heated Agitator (Optional) Fully Contained Flexible Glovebag Fully Contained Sampling Fully Contained Heel Recovery

FilterLab250 KiloLab KILOLAB The FD250 KiloLab Scale Filter has been specifically designed to enable fully contained

The filter dryer incorporates: 20 Litre Slurry Capacity 6 Litre Cake Capacity Pneumatically Driven Agitator Hydraulic

Contained Glovebox Discharge Fully Contained Sampling Fully Contained Heel Recovery FD350 High Potency The FD350 High

Capacity 20 Litre Cake Capacity Electrically Driven Agitator Hydraulic Contained Glovebox Discharge Fully Contained

Mobile FD450 The FD450 Filter Dryer has been specifically designed to enable fully contained The FD450 incorporates: 80

Glove Box Discharge Sampling and Heel Recovery 0.16m2 Filter Area

8 FilterLab250 KiloLab KILOLAB The FD250 KiloLab Scale Filter has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The filter dryer incorporates: 20 Litre Slurry Capacity 6 Litre Cake Capacity Pneumatically Driven Agitator Hydraulic Raise/Lower of Agitator Nitrogen Purged Double Mechanical Seal and Flexible Alloy C22 Bellows Heated Agitator Fully Contained Glovebox Discharge Fully Contained Sampling Fully Contained Heel Recovery FD350 High Potency The FD350 High Potency has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The FD350 High Potency incorporates: 50 Litre Slurry Capacity 20 Litre Cake Capacity Electrically Driven Agitator Hydraulic Raise/Lower of Agitator Nitrogen Purged Double Mechanical Seal and Flexible Alloy C22 Bellows Heated Agitator Fully Contained Glovebox Discharge Fully Contained Sampling Fully Contained Heel Recovery Strip Sight Glass on Side for Measuring Cake Depth Vessel Tilt Mechanism Fully Mobile FD450 The FD450 Filter Dryer has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The FD450 incorporates: 80 Litre Slurry Capacity 30 Litre Cake Capacity Electrically Driven Agitator Hydraulic Raise/Lower of Agitator Fully Contained Glove Box Discharge Sampling and Heel Recovery 0.16m2 Filter Area

PILOT SCALE Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD630 630 0.

Raise Lower Heated Agitator Solid Discharge System - Single Chamber Glovebox Contained Heel Recovery and Sampling Double Mechanical Seal and Bellows

9 PILOT SCALE Filter Dryer Models The Standard Range Model Dia mm Filter Area m2 Slurry Capacity Litres Cake Capacity Litres FD or or 90 FD or or 120 FD FD FD FD FD Filter Dryer FD720 The FD720 Filter Dryer has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yeild. The FD720 incorporates: 260 Litre Slurry Capacity 80 Litre Cake Capacity Electrically Driven Variable Speed Agitator Hydraulic Power Pack for Agitator Raise Lower Heated Agitator Solid Discharge System - Single Chamber Glovebox Contained Heel Recovery and Sampling Double Mechanical Seal and Bellows Filter Dryer FD875 The FD875 Filter Dryer has been specifically designed to enable fully contained processing of active pharmaceuticals, yet at the time maximises product yield. The FD875 incorporates: 400 Litre Slurry Capacity 120 Litre Cake Capacity Retractable Agitator Assembly Hydraulic Power Pack for Agitator Raise Lower Solid Discharge System - Single Chamber Glovebox Contained Heel Recovery and Sampling Double Mechanical Seal and Bellows

Customer Service Repair Work to Existing Units Complete Modification Service Part Exchange Purchase World Wide Customer Service Round The Clock Technical Assistance Installation & Commissioning

10 Customer Service Repair Work to Existing Units Complete Modification Service Part Exchange Purchase World Wide Customer Service Round The Clock Technical Assistance Installation & Commissioning Service Contracts Spares Philip Morris our Commissioning and Site Service Manager joined GL Filtration Limited as Commissioning and Site Services Manager. Philip has vast experience in the manufacture, testing, commissioning and after sales service of Nutsch Type Filters, Filter Dryers, Pan Dryers and similar equipment. For further information: How to find us South M18 Exit junction 1 off M18 south. Take 3rd exit off roundabout, follow signs for Bawtry/Tickhill for around 6 miles.(going straight ahead at the Queens Hotel crossroads, Maltby). Upon entering Tickhill, follow main road into Tickhill centre. At the monument take a right turn heading towards Bawtry. 2 miles down road take a left turn onto Stripe Road, (Rossington). Follow road for around 3 miles, coming to a small roundabout. Take first exit off roundabout, following the road for approximately 1 mile. Coming to the end off the road, take a right turn onto Bankwood Lane. Approximately 100 yards, take the first right onto Bankwood Lane Industrial Estate. Follow the road to the bottom where the road turns to the right. GL Filtration are the corner unit. WELCOME! North M18 Exit junction 1 off M18 south. Take 1st exit off roundabout, follow signs for Bawtry/Tickhill for around 6 miles. (Going straight ahead at the Queens Hotel crossroads, Maltby). Upon entering Tickhill, follow main road into Tickhill centre. At the monument take a right turn heading towards Bawtry. 2 miles down road take a left turn on to Stripe Road, (Rossington). Follow road for around 3 miles, coming to a small roundabout. Take first exit off roundabout, following the road for approximately 1 mile. Coming to the end off road, take a right turn onto Bankwood Lane. Approximately 100 yards, take the first right onto Bankwood Lane Industrial Estate. Follow road down to the bottom where the road turns to the right. GL Filtration are the corner unit. WELCOME!

11 GL Filtration Limited Unit 11 Oakleaf Industrial Estate Bankwood Lane Rossington Doncaster South Yorkshire DN11 0PS United Kingdom Tel: Fax:

Michal Jaworski Agent Czech Republic and Poland Mobile: +48 660 664 868 E-mail: michal.jaworski@sylkat.com Phillipe Verbert Agent Benelux Mobile: +32 475 79 51 28 E-mail: philippe@verbert.

12 Michal Jaworski Agent Czech Republic and Poland Mobile: Phillipe Verbert Agent Benelux Mobile: Alain Guillot Agent France et Suisse Mobile: +33 (0) c-alain.guillot@wanadoo.fr Sebastian Sancho Agent Spain Office Phone: Mobile: sebastian.sancho@aiqs.es Shraga Hasid Ltd Agent Isreal Tel: shraga@shragahasid.com Sentinel Process Systems Inc Agent USA Tel: sales@sentinelprocess.com Sepratech International Agent Ireland Tel: + 44 (0) Mobile: +44 (0) PDe6@aol.com GL FILTRATION Ltd World Leaders In Solid-Liquid Separation

FILTER DRYERS FROM PSL

Filter Dryers FILTER DRYERS FROM PSL HIGH CONTAINMENT DIRECT HEEL RECOVERY REFLUX CLEANING cgmp CIP EFFICIENT DRYING PSL's filter dryers provide optimum levels of safety and quality and are designed to