SHUR/Cut. Microtomes. Innovations for Science 012.0

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1 012.0 SHUR/Cut Microtomes Innovations for Science

2 SHUR/Cut.... At the forefront of m SHUR/Cut SC2500 Non-Retracting & SC3500 Semi-Automa to automate specimen-arm advance / return & instantaneous switching between operator to focus on hand sectioning. Solid construction and precision engineer Recessed staging area for convenient placement of blades, brushes and other ancillary tools. Motorized Specimen arm has a 70 mm vertical stroke and a 20 mm motorized horizontal extension. Powerful over-dimensional cross roller-bearing guideways provide exceptional stability Instrument Display Panel SC2500 All models come standard with our most popular blade holder that accepts both high and low profile blades. Lateral displacement feature facilities the use of the entire disposable blade without moving the actual blade in the holder. The SC2500 has the same motorized trimming & sectioning thickness setting features as the SC3500 including one-speed specimen-arm advance & return; but, for the cost conscious budget without the added benefits of the specimen-arm position memory feature and the ergonometric hand-pad controller included with the SC3500. The control panel is positioned on the left front of the instrument for fingertip switching between sectioning & trimming functions. To increase or decrease the thicknesses, simply press the + and - signs accordingly. The specimen arm is easily advanced & returned by pressing the appropriate direction arrows. All models also display the number of revolutions and the total amount advanced since the last reset. When switching from TRIM to SECT, the counter automatically resets. SHUR/Cut (SC3500) Microtome shown with (SC1000) x/y/z orientation mechanism, (SC2000A) Quick-Release Cassette Clamp and SC3000-HL interchangable High/Low Profile Blade Holder. Spacious debris collection tray is securely held into position by several magnets yet easy to remove for emptying and cleaning.

3 otorized & manual sectioning innovation tic Retracting Microtomes incorporate the latest electronic technology operator selectable trimming & sectioning mode thicknesses while allowing the ing make SHUR/Cut a true work-horse in high production laboratory settings. Kydex plastic housing is xylene, dent & scratch resistant for long-term care and appearance Conveniently positioned handwheel locking mechanism for efficient thumb control locking of the specimen arm in the uppermost position. Hand-Pad Controller SC3500 Instrument Display Panel Secondary handwheel locking mechanism secures the specimen arm in any position The user-friendly hand-pad of the SC3500 also allows the operator to store separate trimming and sectioning thicknesses. To switch from one mode to the other, simply press the appropriate embossed switch. 2-Speed motorized specimen forward / reverse feed-function rapidly advances a tissue block for cutting or returning to the rear for inserting a new block. Inclined hand-pad, adjustable feet and a long cord allow the hand-pad controller to be comfortably positioned on either side of the microtome for maximized personal comfort. Retraction can be turned On / Off by the push of a button. Automatic specimen positioning memory function facilitates removing a block for rehydration or cooling, and, with a push of a button after re-inserting the block into the specimen clamp, the electronic memory will reposition the specimen back to the original location.

4 SHUR/Cut... Ergonomically Designed To The SC4500 Electronic Microtome is built with the user and specimen in mind. M operator comfort and protection, or, can be operated manually for the specimen that requires a technological advances in electrical, mechanical & software engineering. SC4500 Instrument Display Panel Push-button switching between manual, continuous & single stroke cutting modes is managed by the intuitive hand-pad with the active mode indicated on the instrument display panel. A readily accessible emergency stop button quickly halts the motor drive when pushed. Motorized operation can also be actuated by the included foot pedal to further reduce repetitive hand motions. SHUR/Cut (SC4500) Microtome shown with (SC1000) x/y/z orientation mechanism, (SC2000A) Quick-Release Cassette Clamp and SC3000-HPLP interchangable High/Low Profile Blade Holder. SAFETY/QUALIT SHUR/Cut Microtomes have been designed standards and have been tested by an indepen instruments are in compliance with IEC

5 Reduce Work-Related Musculoskeltal Issues icroprocessor management of specimen advance, return, trim and sectioning is motorized for special touch. The SC4500 fully automatic retracting microtome features the most modern SC4500 Hand-Pad Controller The SC4500 has an adjustable-speed motorized cutting stroke that can be customized to simulate a manual motion, leaving the operator s hands free to manipulate and guide ribbons. Engineered to provide the utmost in accuracy, efficiency and precise sectioning, the motorized functions are operated by an intuitive hand-pad that provides fingertip control of start/stop, speed control from 30 to 120 rpm and easy switchover between pre-set trimming and sectioning modes. Y STANDARDS to meet international safety and quality dent testing agency to certify that the CE UL CSA C The extra long cable to the hand-pad,the inclined design & the adjustable rear feet allow the hand-pad to be conveniently positioned for user comfort to minimize repetitive motion stress. Automatic specimen positioning memory function facilitates removing a block for rehydration or cooling, and, with a push of a button after re-inserting the block into the specimen clamp, the electronic memory will reposition the specimen back to the original location.

6 TECHNICAL SPECIFICATIONS Section Counter: LCD read-out of # of revolutions & total amount advanced. Reset with a push of a button SC2500 SC3500 SC4500 X X X , in 0.5µm increments X X X , in 1.0µm increments X X X Sectioning/Trimming Settings: 10-20, in 2.0µm increments X X X 20 to 60, in 5.0µm increments X X X 100 to 600, in 50µm increments 20µm X X Horizontal Specimen Advance: 20mm ± 1mm, via stepper motor X X X Vertical Cutting Stroke: 70mm ± 1 X X X Automatic Retraction: Yes, can be turned off X X X X X Specimen Clamp: Quick-Release Type for standard & biopsy cassettes, forward/backward operating lever Quick-Release Type for standard & biopsy cassettes, left to right operating lever C Type Object Holder for larger blocks, Max. size (40x50) mm, screw type Optional Optional Optional Optional Optional Optional Specimen Orientation: X/Y Axes 8 o ; Z Axis 360 o X X X Specimen Arm Locking: Handwheel locking of specimen in uppermost position X X X Secondary 360 o locking mechanism X X X Motorized Specimen Feed: Single-speed forward & return: 730 µm/sec X Two-speed forward & return: 270 µm/sec or 1055 µm/sec X X Motorized Cutting Speed: Variable speed forward & return: 100 µm/sec to 400 µm/sec X PermissIble Storage Temp. Range: 5 o C to 55 o C X X X Depth mm (in) 550 (22) 550 (22) 550 (22) Dimensions: mm (inches) Width mm (in) 420 (17) 420 (17) 420 (17) Height mm (in) 320 (13) 320 (13) 320 (13) Weight: kg(lbs) Microtome, kg (lb) 36 (79) 36 (79) 38 (99) Microtome, crated kg (lb) 45 (99) 46 (101) 46 (101) Manual Operation: X X X Push-Button Switching: Membrane switching between Trimming & Sectioning X X X Motorized Operation: X Foot Pedal Control: Hand-pad control of hand-wheel speed between rpm, with Continuous & Single stroke operating modes For single stroke and continuous operation, Stop Action (Single tap) Electrical Requirements: VAC, 50/60Hz, 77W; VAC, 50/60Hz, 77W X X X X X X Accessories Included: Specimen Orientation Mechanism (SC1000); Quick- Release Clamp (SC2000A); Disposable Blade Holder (SC3000HPLP) that accepts both high & low profile blades; 1-PK of low profile blades (DMB-LP+); Section Waste Tray (SC5000), Dust Cover, Tool Kit, Lubrication Kit, Operator Manual and a sample bottle of PARA/Gard Foot Pedal X X

7 COMPLETE VERSATILITY Specimen Accessories Routine Knife & Blade Holders SC3000K SC1001 SC1000 SC3000-LP, -HP or HPLP DMBH- LP, HP or HPLP SC2000C SC2000B SC2000A CUT3001 DMB-(series) Microtomes SC2500 SC3500 SC4500 SHUR/Cut 2500, Semi-automatic microtome. Instrument mounted membrane touch pad featuring motorized specimen advance/return and push-button setting of and switching between trimming/ sectioning thicknesses. Digital display of # of revolutions and total amount advanced. Includes x/y/z specimen orientation, quick-release clamp, low/high profile combo blade holder, sample packs of high & low profile blades, a bottle of PARA/Gard TM and a debris tray. Voltage: VAC, 50/60Hz, 77W SHUR/Cut 3500, Semi-automatic retracting microtome. Instrument mounted membrane touch pad displays # of revolutions / thickness setting / total amount specimen advanced and whether in trimming or sectioning mode. Repetitive motion hand functions housed in operator positionable handpad for technician comfort and to reduce work-related Neuro-musculoskeletal disorders. Pushbutton setting of cutting thickness, switching between trimming/sectioning modes, 2-speed specimen advance/return and retraction O/O feature. Unique specimen-position memory feature invaluable for remembering a specimen s extended position for removing to chill and then return automatically to the original position with just a push of a button. Includes x/y/z specimen orientation, quick-release clamp, low/high profile combo blade holder, sample packs of high & low profile blades, a bottle of PARA/Gard TM and a debris tray. Voltage: VAC, 50/60Hz, 77W SHUR/Cut 4500, Automatic retracting microtome w/ adjustable-speed motorized cutting stroke. Continuous and single-stroke motorized cutting modes or operate manually for specimens requiring a special touch. Repetitive motion hand functions housed in operator positionable handpad for technician comfort and to reduce work-related Neuro-musculoskeletal disorders. Push-button setting of cutting thickness, switching between trimming/sectioning modes, 2-speed specimen advance/return, O/O retraction feature. Unique specimen position-memory feature invaluable for remembering a specimen s extended position for removing a block to chill and then return automatically to the original position with just a push of a button. Includes x/y/z specimen orientation, quick-release clamp, low/ high profile combo blade holder, foot pedal, sample packs of high & low profile blades, a bottle of PARA/Gard TM and a debris tray. Voltage: VAC, 50/60Hz, 77W Specimen Orientation SC1000 Specimen x/y/z orientation mechanism, 8 SC1001 Fixed Adapter Piece, for applications not requiring x/y specimen orientation Specimen Holders SC2000-A Quick release cassette clamp for most regular and biopsy cassettes, forward/backward operating lever SC2000-B Quick release cassette clamp for most regular and biopsy cassettes, left to right operating lever SC2000-C C Type Object Holder, Screw type cassette clamp for square or rectangular blocks; maximum specimen size (40 x 50)mm (1.5 x 2)in Disposable Blade Holders SC3000K Knife Holder Clamp f/resharpen Knives & Disposable Blade Holders, accepts SC3000A, B & C reusable knives and DMBH, DMBH-HPLP disposable blade holders SC3000-LP Disposable Blade Holder, for low-profile blades SC3000-HP Disposable Blade Holder, for high-profile blades SC3000-HPLP Disposable Blade Holder, for both low and high profile blades DMBH-HPLP SHUR/Sharp Blade Holder for interchangeable use of low and high profile blades (Requires SC3000K Knife Holder & DMB-LP+ or DMB-HP+ Disposable Blades) DMBH SHUR/Sharp Disposable Microtome Blade Holder for TBS SHUR/Sharp heavy duty (DMB-HD) disposable blades DMBH-LP SHUR/Sharp Disposable Microtome Blade Holder, for any low profile disposable blade DMBH-HP SHUR/Sharp Disposable Microtome Blade Holder, for any high profile disposable blade Disposable Blades DMB-LP SHUR/Sharp Disposable Microtome Blades, Low Profile, coated, use TBS SC3000LP & all low profile blade holders, 60/pk, 10pk/cs DMB-LP+ SHUR/Sharp PLUS Disposable Microtome Blades, Premium Quality, Low Profile, coated, use TBS SC3000LP, DMBH-LP, DMBH-HPLP & all competitive low profile blade holders, 60/pk, 10pk/cs DMB-HP SHUR/Sharp Disposable Microtome Blades, High Profile, coated, use TBS SC3000HP, SC3000HL & all competitive high profile blade holders, 60/pk, 10pk/cs DMB-HP+ SHUR/Sharp PLUS Disposable Microtome Blades, Premium Quality High Profile, coated, use TBS SC3000HP, SC3000HL & DMBH-HP, DMBH-HPLP & all high profile blade holders, 60/pk, 10pk/cs Reusable Knives SC3000-A Conventional Steel Knife, 16cm, C profile, w/storage case SC3000-B Conventional Steel Knife, 16cm, D profile, w/storage case SC3000-C Tungsten-Carbide Edged Knife, 16cm, D profile, w/storage case Accessories & Consumables SC5000 Waste tray, for convenient collection and cleaning of paraffin cutting scraps SC4000-FP Foot Pedal, to reduce hand/instrument interaction

8 Microtome and Cryostat Consumables & Supplies TBS manufactures a comprehensive line of microtomes, cryostats, related accessories & supplies to enhance your cutting experience. Visit for more information on our innovative products or contact TBS at to arrange for a demostration. TFM Tissue Freezing Medium SHUR/Track Processing & Embedding Cassettes TMD Tissue Marking Dye SHUR/Lube Microtome Lubricating Oil SHUR/Mark Marking Pens POLY/Fin Paraffin Wax SHUR/Freeze Freon SHUR/Sharp Blades Brushes PARA/Gard Ordering Information: Cat # Description TFM-5 TFM Tissue Freezing Medium, Embedding matrix for frozen sections; CLEAR, RED, YELLOW, GREEN, & BLUE colors; Includes: 4 oz. of each color/ea, 4 ea/cs TFM-C TFM-(color) TMD-7 TMD-(color) H-LUB FRZ PF PF-15KG BR-ST SM-PPC-(color) BC-(color) MP-(color) PG DMB-(size) TFM Tissue Freezing Medium, Embedding matrix for frozen sections; CLEAR (C); 4 oz/ea, 12 ea/cs TFM Tissue Freezing Medium, available in individual colors of: CLEAR, RED, YELLOW, GREEN, & BLUE; Includes: 4 oz. of each color/ea, 4 ea/cs TMD Tissue Marking Dyes for marking margins & multiple biopsies, ORANGE, BLACK, BLUE, YELLOW, RED, PURPLE & GREEN dyes; Includes: 2oz. of each dye/ea; 4ea/cs TMD Tissue Marking Dyes, available in individual colors of: ORANGE, BLACK, BLUE, YELLOW, RED, PURPLE & GREEN; Includes: 2oz. of each dye/ea; 4ea/cs SHUR/Lube Microtome Lubricating Oil, cleans, lubricates and protects in extreme temperature environments; 3/4oz/ea, 6ea/cs SHUR/Freeze Cryogen spray with nozzle, 12 oz. can w/10 oz. fill, does not contain dichlorodifluoromethane; 12 ea/cs. See MSDS for HAZ-MAT handling requirements on Air Shipments POLY/Fin Paraffin; 8x1 kg/cs (17.6 lbs) POLY/Fin Paraffin; 15 kg drum (33lbs) Brush Set, w/fine flexible bristles, 1/8,1/4 & 3/8 (width); 1ea/pk SHUR/Track Processing & Embedding cassettes w/channel track hinge. Specifically designed and quality controlled for use w/both automated labeling instruments and hand marking devices. Detachable lids are removed and packaged separately; Colors Available: White (W), Blue (B), Green (G), Grey (GY), Pink (P), Peach (PE), Yellow (Y), Tan (T), Aqua (A), & Lilac (L); 1000/cs SHUR/Track Biopsy Cassettes w/channel track hinge. Specifically designed and quality controlled for use with both automated labeling instruments and hand marking devices. Detachable lids are removed and packaged separately. Perforations (0.75 x 0.75mm) occupy over 69% of surface area. Colors Available: White (W), Blue (B), Green (G), Grey (GY), Pink (P), Peach (PE), Yellow (Y), Tan (T), Aqua (A), & Lilac (L); 500/cs SHUR/Mark Marking pen, specify -B for BLACK or -R for RED, for labeling slides or cassettes; 12/pk, 5pk/cs PARA/Gard, liquid paraffin repellent for countertops and equipment; 4 oz. pump bottle/ea, 6 ea/cs. See MSDS for HAZ-MAT handling requirements on Air Shipments SHUR/Sharp Disposable Microtome Blades; specify size DMB-LP, DMB-LP+, DMB-HP and DMB-HP+ Please visit our website for additional product information, technical bulletins, career opportunities, MSDS files, etc. Distributed By: Specifications are current at time of publication; however, they are subject to change without notification. Please contact our North Carolina office or one of our distributors for current prices and availability. Innovations for Science, SC2500, SC3500, SC4500, SHUR/Cut, SHUR/Sharp, SHUR/Freeze, SHUR/Track, PARA/Gard, TFM, TMD are trademarks and TBS is a registered trademark of Triangle Biomedical Sciences, Inc., Durham, North Carolina, USA. Printed in U.S.A. June 21, 2011 Version 1.42

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