Class II Biological Safety Cabinets The World's Leading Energy Efficient, Quiet, and Compact Biosafety Cabinet.

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1 Airstream Class II, Biosafety Cabinet, Model AC2-4K8 Class II Biological Safety Cabinets The World's Leading Energy Efficient, Quiet, and Compact Biosafety Cabinet.

Voltage Free Relay Contact Airflow Sensor

High-end Accusense sensor made by Degree

wipe Raised Arm Rest Helps prevent grille

2 Voltage Free Relay Contact Airflow Sensor Zero volt exhaust and alarm contact Monitors real-time airflow for safety Alert the user if airflow is insufficient High-end Accusense sensor made by Degree C Esco AC2 Airflow: OK I: 0.65 m/s Socket: ON 15:34 Sash: OK D: 0.41 m/s SentinelTM Gold Microprocessor Controller Displays all safety information on one screen Centered and angled down for easy reach & viewing Selectable Quickstart mode for fast operation Counter-balance Sash Window Aerosol tight window seal Manual window with counter-balance system Unique Stainless Steel Side Walls Large corner radius for easy cleaning Easy to reach service fixture and outlets 2 Single Piece Work Tray Recessed to contain spillage Sloped perimeter that s easy to wipe Raised Arm Rest Helps prevent grille blocking Comfortable working posture Available in 1.2, 1.5 and 1.8 meter width (4 5 and 6') Removable Paper Catch Easy to clean Optional pre-filter can be fitted Class II Biological Safety Cabinets

RS 232 Serial Interface Port DUAL Energy Efficient DC ECM Motor Send

energy efficient Class II Biosafety Cabinet in the world 0% Energy

fluctuations & filter loading Standby mode to further reduce power

999% Creates ISO Class 3 work zone instead of industry-standard ISO

growth to improve safety 3 Optional Hydrogen Peroxide Injection Port

for easy decontamination Angled Drain Pan Easy to clean Does not harbor

Filtration Electrical Safety AS180.22, Australia ISO 14644.

3 RS 232 Serial Interface Port DUAL Energy Efficient DC ECM Motor Send operational information to Building Management System (BMS) The most energy efficient Class II Biosafety Cabinet in the world 0% Energy savings compared to AC motor Stable airflow, despite building voltage fluctuations & filter loading Standby mode to further reduce power consumption by 60% H14 Filter H14 Filter with efficiency of % Creates ISO Class 3 work zone instead of industry-standard ISO Class 5 Powder Coat Silver-ion impregnated powder coat Inhibit microbial growth to improve safety 3 Optional Hydrogen Peroxide Injection Port Easily connect to VHP/HPV Generator Combined with sealed front window for easy decontamination Angled Drain Pan Easy to clean Does not harbor contaminants Standards Compliance Biosafety Cabinet Air Quality Filtration Electrical Safety AS180.22, Australia ISO Class 3, Worldwide EN-1822 (H14), Europe IEC , Worldwide IEST-RP-CC001.3, USA EN , Europe JIS B9920 Class 3, Japan JIS IEST-RP-CC00, USA UL , USA BS5295, Class 3, Japan IEST-RP-CC034.1, USA CAN / CSA-22.2, No DIN EN 12469, Europe SANS 12469, South Africa

Cabinet Filtration System Performance Envelope Test of AC2-K Approximately ⅓ of the air in the common plenum is exhausted through the ULPA filter to the room.

Near the work surface, the downflow splits. About half goes to the front grille, and half goes to the rear grille.

The design was optimized to give large performance envelope, that provides operator and product protection at wide Inflow and Downflow variation from the Nominal point.

Multi Language: English, French, German, Spanish, Italian. Esco AC2 Airflow: OK I: 0.65 m/s Socket: ON Diagnostics button, to easily check the cabinet operating parameters and assist servicing.

60 m/s Downflow Velocity Nominal Airflow Personnel / Product Protection Area of Personnel and Product Protection Color coded LED: green for fan; blue for lights and outlets; and orange for UV lamp.

4 Cabinet Filtration System Performance Envelope Test of AC2-K Approximately ⅓ of the air in the common plenum is exhausted through the ULPA filter to the room. The remaining ⅔ of the air is passed through the downflow ULPA filter and into the work area as a vertical laminar flow air to create ISO Class 3 work surface and prevents cross contamination. Near the work surface, the downflow splits. About half goes to the front grille, and half goes to the rear grille. A small portion enters the the side capture zones to prevent dead air corners (small blue arrows). The design was optimized to give large performance envelope, that provides operator and product protection at wide Inflow and Downflow variation from the Nominal point. H14-filtered air Unfiltered / potentially contaminated air Room air / Inflow air LCD simultaneously displays time, airflow & sash status,inflow and downflow velocities, and status remarks. Multi Language: English, French, German, Spanish, Italian. Esco AC2 Airflow: OK I: 0.65 m/s Socket: ON Diagnostics button, to easily check the cabinet operating parameters and assist servicing. Large touchpad control buttons provide good tactile feedback fpm m/s Downflow Velocity Nominal Airflow Personnel / Product Protection Area of Personnel and Product Protection Color coded LED: green for fan; blue for lights and outlets; and orange for UV lamp. No Personnel / Product Protection Area of no Personnel and Product Protection Programmable UV light timer extends UV lamp life. AC2-4K8 with DC ECM blower Typical BSC with AC Blower Savings Units Watt 2000 Hours Energy kwh Energy cost in USA at $ 0.10 / kwh USD Energy cost in Australia at $ 0.04 / kwh AUD CO2 released in USA at 1 lbs / kwh lbs CO2 emission in Australia at 0.35 Kg / kwh Kg Class II Biological Safety Cabinets :34 Sash: OK D: 0.41 m/s Hours of Operation in a year 120 Nominal 0.41, 0.65 m/s (81, 128 fpm) AC2-K Cabinets Save Money and Environment Instantaneous Power Description 120 fpm m/s Inflow Velocity Ambient air is pulled through front grille to create inflow, without going into the work surface. Inflow is joined by half of the downflow, to create front air curtain that is fine-tuned to create a large performance envelope. The combined air stream travels through the back air column towards the blower.

Model AC2-K Biological Safety Cabinet Engineering Drawing 4 feet = 553 mm (21.8 ) 310 mm (12.2 ) 21 23 22 24 250 mm (9.8 ) 150 mm (5.9 ) 12 13 5 14 1 15 1400 mm (55.

Laminated Counter-balance Sash Window 4. Stainless Steel Single-piece Work Tray 5. Electrical Panel 6. Energy Efficient Fluorescent Lamps. Stainless Steel Side Walls 8.

5 Model AC2-K Biological Safety Cabinet Engineering Drawing 4 feet = 553 mm (21.8 ) 310 mm (12.2 ) mm (9.8 ) 150 mm (5.9 ) mm (55.1 ) mm (25. ) 1220 mm (48.0") 1340 mm (52.8") mm (22.5 ) 6 mm (30.2 ) 823 mm (32.4 ) Key Lock 2. Esco Sentinel TM Gold Microprocessor Control System 3. Laminated Counter-balance Sash Window 4. Stainless Steel Single-piece Work Tray 5. Electrical Panel 6. Energy Efficient Fluorescent Lamps. Stainless Steel Side Walls 8. IV Bar Retrofit Kit Provision 9. Service Fixture Retrofit Kit Provision 10. Standard Electrical Outlet Retrofit Kit Provision 11. Stainless Steel Arm Rest 12. Exhaust Collar (Optional) 13. Exhaust H14 Filter 14. DC ECM Downflow Blower 15. DC ECM Exhaust Blower 16. Downflow H14 Filter 1. Downflow Sensor 18. UV Lamp Provision 19. Optional Solenoid Valve 20. Optional Steris VHP / Bioquell HPV Port 21. Exhaust Sensor 22. Voltage Free Relay Contact 23. RS 232 Serial Interface Port 24. Power Inlet Comprehensive Performance Testing at Esco Every Airstream AC2-K model manufactured by Esco is individually tested, documented by serial number and validated with the following test methods: Inflow and downflow velocity PAO aerosol challenge for filter integrity Airflow pattern visualization Electrical safety to IEC Additional KI-Discus containment and microbiological testing are performed on statistical sampling basis.

6 AC2-K TECHNICAL SPECIFICATIONS Stainless Steel Side: VAC, 50/60 Hz AC2-4K Nominal Size 4 ft (1.2 m) Width 1340 mm (52.8") External Dimensions (W x D x H) Depth without arm rest 6 mm (30.2") Depth with arm rest 823 mm (32.4") Height 1400 mm (55.1") Gross Internal Dimensions (W x D x H) Usable Work Area Width 1220 mm (48.0") Depth 580 mm (22.8") Height 654 mm (25.") 0.56 m 2 (6.1 sq.ft.) Tested Opening 15 mm (6.9") Average Airflow Velocity Airflow Volume Inflow Downflow Inflow Downflow Exhaust Required Exhaust with Optional Thimble Exhaust Collar 0.65 m/s (128 fpm) 0.41 m/s (81 fpm) 500 cmh (294 cfm) 1026 cmh (604 cfm) 500 cmh (294 cfm) 554 cmh (326 cfm) 6 Static Pressure for Optional Thimble Exhaust Collar 38 Pa / 0.12 in H 2 O ULPA Filter Typical Efficiency Sound Emission per AS Fluorescent Lamp Intensity >99.999% at 0.1 to 0.3 micron, ULPA as per IEST-RP-CC001.3 USA >99.999% at MPPS, H14 as per EN 1822 EU 61 dba 866 lux (80 foot candles) Cabinet Construction Main body Work Zone Side Walls 1.2 mm (0.05") 18 gauge electro-galvanized steel with white oven-baked epoxy-polyester Isocide TM antimicrobial powder-coated finish 1.5 mm (0.06") 16 gauge stainless steel, type 304, with 4B finish 1.5 mm (0.06") 16 gauge stainless steel, type 304, with 4B finish Electrical Cabinet Full Load Amps (FLA) 10 Heat Load (BTU/Hr) 682 Nominal Power Consumption (W) 223 Net Weight ** Shipping Weight ** Shipping Dimensions, Maximum (W x D x H)** 236 Kg (520 lbs) 260 Kg (53 lbs) 1450 x 880 x 160 mm (5.1" x 34.6" x 69.3") Shipping Volume, Maximum ** 2.25 m 3 (9.5 ft 3 ) *Noise reading in open field condition / anechoic chamber. Noise reading in normal room varies by room size, layout, and background noise, but may reach roughly 3-4 dba above these values. **Cabinet only, excludes optional stand. Class II Biological Safety Cabinets

7 Accesories for AC2-K Biological Safety Cabinets Stainless Steel Side Wall Anti-blowback Valve 10" AC2-4K ABBV-10P ABBV-10P Exhaust Ducting Tri-safe Exhaust Collar with Alarm Thimble Exhaust Collar TEM ECO-AC24-TU Exhaust Damper B2-DAMPER TEM-4 Hydrogen Peroxide Decontamination Kit VHP In Port (Ø 1 ) VHP Out Top Box for Cabinet WITH Exhaust Collar Installed (Ø 1 ) VHP Out Top Box for Cabinet WITHOUT Exhaust Collar Installed (Ø 1 ) VHP-IN PORT VHP-ECO/OUT 4FT VHP OUT TOP BOX 4ft ECO-AC2-_-TU UV Lamp UV-30A-L Work Zone IV Bar IV Pre-filter on Paper Catch PF B2-DAMPER Electrical Outlet Direct Mounted EO-H_ EU SF-Gas-20 mm and Solenoid Valve SF-1G and SL-VALVE EU SF-Vacuum-20 mm SF-1V Service Fixtures EU SF-Air-20 mm SF-1A EU SF-Nitrogen-20 mm SF-1N VHP-IN PORT EU SF-Water-20 mm SF-1W EU SF-Universal-22 mm SF-2U Fixed Stand with Leveling Feet, 28 height SAL-4A0 Gen Fixed Stand with Leveling Feet, 34 height SAL-4B0 Gen VHP-ECO/OUT Fixed Stand with Caster Wheels, 28 height SPC-4A0 Gen Support Stands, Ships Flat Fixed Stand with Caster Wheels, 34 height SPC-4B0 Gen Telescopic Stand with Leveling Feet, 1 adjustment STL-4A VHP OUT TOP BOX Telescopic Stand with Caster Wheels, 1 adjustment STC-4A Motorized Height Stand with Caster Wheels SPM-4A_ Misc IQ OQ Protocol UV-_A-L SF-1_ SF-2U22 EO-H_ PF-_ IV-_ SPC-_A0 Gen2 SAL-_A0 Gen2 STC-_A0 SPM-_A_ IQ-OQ

ESCO GLOBAL NETWORK 8 ART Equipment Biological Safety Cabinets CO 2 Incubators Cold Storage Compounding Pharmacy Equipment Containment / Pharma Products Ductless Fume Hoods Lab Animal Research

of Companies is a global life sciences tools provider with sales in over 100 countries. The group is active in lab equipment, pharma equipment and medical devices.

Sales, service and marketing subsidiaries are located in 12 major markets including the US, UK, Singapore, Japan, China and India.

8 ESCO GLOBAL NETWORK 8 ART Equipment Biological Safety Cabinets CO 2 Incubators Cold Storage Compounding Pharmacy Equipment Containment / Pharma Products Ductless Fume Hoods Lab Animal Research Products Laboratory Fume Hoods Laboratory Incubators Laboratory Ovens Laminar Flow Cabinets Laboratory Freeze Dryers PCR Cabinets PCR Thermal Cyclers Powder Weighing Balance Enclosures The Esco Group of Companies is a global life sciences tools provider with sales in over 100 countries. The group is active in lab equipment, pharma equipment and medical devices. Manufacturing facilities are located in Asia and Europe. R&D is conducted worldwide spanning the US, Europe and Asia. Sales, service and marketing subsidiaries are located in 12 major markets including the US, UK, Singapore, Japan, China and India. Regional distribution centers are located in the US, UK, and Singapore. Life Science Chemical Research Assisted Reproductive Technology (ART) Pharmaceutical Equipment General Equipment Esco Technologies, Inc. 903 Sheehy Drive, Suite F, Horsham, PA 19044, USA Toll-Free USA and Canada Tel Fax eti.sales@escoglobal.com Esco Micro Pte. Ltd. 21 Changi South Street 1 Singapore 486 Tel Fax mail@escoglobal.com Esco Global Offices: Sydney, Australia Manama, Bahrain Beijing, China Chengdu, China Guangzhou, China Shanghai, China Biological Safety Cabinet_AC2-K_Brochure_vA_ Esco can accept no responsibility for possible errors in catalogues, brochures and other printed materials. Esco reserves the right to alter its products and specifications without notice. All trademarks and logotypes in this material are the property of Esco and the respective companies. Kowloon, Hong Kong Bangalore, India Delhi, India Mumbai, India Jakarta, Indonesia Rome, Italy Osaka, Japan Kuala Lumpur, Malaysia Melaka, Malaysia Manila, Philippines Moscow, Russia Singapore Midrand, South Africa escoglobal.com LIVE SUPPORT Seoul, South Korea Bangkok, Thailand Barnsley, United Kingdom South Yorkshire, United Kingdom Philadelphia, PA, USA Hanoi, Vietnam Esco Micro Pte Ltd Cert. No: PT Esco Bintan Indonesia Cert. No: /E PT Esco Bintan Indonesia Cert. No: Q2N

CelCulture. Cradle for Beautiful Cells. CelCulture Water-Jacketed CO 2 Incubator

CelCulture. Cradle for Beautiful Cells. CelCulture Water-Jacketed CO 2 Incubator 1 Cradle for Beautiful Cells Welcome to Esco Esco s Vision is to provide enabling technologies for scientific discoveries to make human lives healthier and safer. A leader in the development of controlled