Corporate Profile 2017

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1 Corporate Profile 2017

2 Top Message Corporate Overview Aiming to realize a Healthcare Consortium that supports a fresh life for all. Denroku Ishiguro Representative Director & Chairman Hiroyuki Kanome Representative Director & Deputy Chairman (As of June 27, 2017) Corporate Name: Address: Alfresa Holdings Corporation 1-1-3, Otemachi, Chiyoda-ku, Tokyo , Japan Established: September 29, 2003 Business Domain: Capital: Management of subsidiaries that deal with wholesaling, manufacturing, marketing and import/export of pharmaceuticals, diagnostic reagents, medical devices/equipment,, and operating dispensing pharmacies and conducting related businesses 18,454 million With Our Philosophy to create and deliver a fresh life for all, the Alfresa Group engages in reliable, safe, and sincere business practices. Net Sales: 2,551,801 million (Fiscal year ended March 31, 2017) Directors and Members: We consider our social mission is to contribute to society where we are operating business by supporting various aspects of medical care in Japan, including distribution. In addition to the stable distribution of pharmaceuticals, we strive to realize a Healthcare Consortium that provides products and services in every health-related field, through expanding our areas of related businesses and fostering strategic collaborations with other companies. Denroku Ishiguro Hiroyuki Kanome Representative Director & Chairman Representative Director & Deputy Chairman Kimiko Terai Director (Outside Director) Yoichiro Yatsurugi Director (Outside Director) Shiho Konno Director (Outside Director) As the Japanese medical care system undergoes major reform, the Alfresa Group announced the Mid-term Management Plan Break Through to Tomorrow in May We are currently moving forward with the plan, aiming to reform ourselves to stay ahead of the changes. To continue being a corporate group indispensable to society, the Alfresa Group will strive to further enhance its corporate value through business activities that meet the needs of the times. Taizo Kubo Representative Director & President Taizo Kubo Shunichi Miyake Koichi Masunaga Yasuki Izumi Ryuji Arakawa Hisashi Katsuki Representative Director & President Director, Deputy President Director, Deputy President Director, Senior Vice President & Executive Officer Director, Vice President & Executive Officer Director Kenji Kuwayama Yuji Noguchi Seisui Kamigaki Yoshitaka Kato Member (Standing) Member (Outside) Member (Outside) Member (Outside) 1 Corporate Profile 2017 Corporate Profile

3 Principles Responding to all healthcare needs by exerting the Group s comprehensive strengths Realization of a Healthcare Consortium The realization of a Healthcare Consortium means the establishment of a system that can contribute to people s lives and health by forming alliances not only with Group companies but also with other firms in the healthcare business to offer comprehensive medical care and healthcare information, products and services. Self-medication Cure Diagnosis,Treatment With the realization of a Healthcare Consortium that provides products and services in every health-related field as Our Vision under its principles, the Alfresa Group works as one to drive efforts toward its materialization while generating synergy. We will strive to respond to all the healthcare needs of patients as well as other people by enhancing our ethical pharmaceutical supply chain and further expanding our business fields and areas. The Alfresa Group s Principles Our Philosophy Manufacture Wholesale Retail Selfmedication Selfmedication pharmaceuticals pharmaceuticals Dispensing pharmacies, Medical services, Medical devices Medical devices Diagnostic reagents Diagnostic reagents We create and deliver a fresh life for all. Our Vision We aim to become a Healthcare Consortium that provides products and services in every health-related field. Our Promises Reliability Safety Sincerity We always maintain the stable supply of reliable products and services that satisfy our customers. We strive to maintain and improve a safe and comfortable working environment, respect individual characteristics and personalities and create a healthy corporate culture. We raise corporate value as a corporate group operating in the healthcare sector to meet shareholders expectations. We conduct proper trade under fair, transparent and free competition. We strive to protect personal information entrusted by our customers and business partners and important company information, work to widely and proactively communicate with society, and implement appropriate and timely information disclosure. We contribute to society through our business operations, proactively carry out social contribution activities in local communities, and actively and voluntarily address global environmental issues. 3 Corporate Profile 2017 Corporate Profile

4 Business Domain Contributing to people s lives and health in a wide range of business areas The Alfresa Group s main businesses are the Pharmaceuticals Wholesaling Business, the Self-Medication Products Wholesaling Business, the, and the. We are striving for the realization of a Healthcare Consortium through the development of various businesses relating to health and medical care to contribute to people s health. Self-Medication Products Wholesaling Business Focusing on over-the-counter drugs, we deliver health foods, supplements and other products to drug stores and pharmacies. We meet customer needs with a full product lineup, a reliable supply system and value-added marketing activities, including proposals on how to create optimal storefronts. Pharmaceuticals Wholesaling Business Alfresa Group's net sales From a comprehensive perspective encompassing prevention, diagnosis, and treatment, we and market high-quality active pharmaceutical ingredients, pharmaceuticals, diagnostic reagents, and medical devices, that meet GMP* and QMS* requirements. We research, develop,, and market unique and distinctive products, and undertake consigned manufacturing of pharmaceuticals. Focusing on ethical pharmaceuticals, we deliver a wide range of products, including diagnostic reagents and medical devices/equipment, from our high-capacity distribution centers nationwide to hospitals, clinics, and dispensing pharmacies. In addition, our sales force with an extensive knowledge provides support to our customers. We contribute to the health of local residents by meeting the diverse needs of customers. 2, * GMP: Good Manufacturing Practice, standards for manufacturing control and quality control of pharmaceuticals and quasi-drugs * QMS: Quality Management System, standards for manufacturing control and quality control of medical devices and external diagnostic reagents Pharmaceutical r Customer support Medical institutions, Hospitals and clinics Pharmaceutical companies pharmaceuticals, Distribution pharmaceuticals, Dispensing pharmacies Drug stores All people 30.2 The Alfresa Group is actively expanding its business areas toward the realization of a Healthcare Consortium. We are meeting a variety of medical needs through our dispensing pharmacy business and other medical-related businesses. As community-based pharmacies, our dispensing pharmacy business strives to further deliver added value. 5 Corporate Profile 2017 Corporate Profile

5 Group Network Pharmaceuticals Wholesaling Business QINGDAO NESCO MEDICAL CO., LTD. (Qingdao, Shandong, China) Alfresa Corporation TS Alfresa Corporation Odashima Limited Kinichiro Odashima, President 2-18, Kuko-minami, Hanamaki, Iwate Prefecture Kowa Pharmaceuticals Co., Ltd. Koichi Masunaga, President 7, Kanda-Mitoshirocho, Chiyoda-ku, Tokyo Kenzo Edahiro, President , Shoko Center, Nishi-ku, Hiroshima, Hiroshima Prefecture Yasuo Takita, President , Kikutamachi Oroshi, Koriyama, Fukushima Prefecture Shikoku Alfresa Corporation Meisho Co., Ltd. RYUYAKU CO., LTD. Keiji Kawashima, President , Fuke Kou, Kokubunjicho, Takamatsu, Kagawa Prefecture Kenji Orimoto, President Ha 1, Muryoji-machi, Kanazawa, Ishikawa Prefecture Tadashi Inamine, President 5-6-5, Makiminato, Urasoe-shi, Okinawa Prefecture Alfresa Medical Service Corporation Seiji Nakamura, President , Uchikanda, Chiyoda-ku, Tokyo SPD business (contract distribution service in hospitals) and wholesaling of medical materials Alfresa Fine Chemical Corporation (Akita Prefecture) Odashima Limited (Iwate Prefecture) Self-Medication Products Wholesaling Business Meisho Co., Ltd. (Ishikawa Prefecture) Alfresa Pharma Corporation (Osaka Prefecture) Kowa Pharmaceuticals Co., Ltd. (Fukushima Prefecture) Alfresa Healthcare Corporation Hisashi Katsuki, President , Nihonbashi-Honcho, Chuo-ku, Tokyo Self-medication products wholesaling business Mogi Pharmaceutical Co., Ltd. Yusuke Mogi, President 3-9-7, Nihonbashi-Honcho, Chuo-ku, Tokyo Self-medication products wholesaling business TS Alfresa Corporation (Hiroshima Prefecture) Sannova Co., Ltd. (Gunma Prefecture) Nihon Apoch CO., LTD (Saitama Prefecture) Alfresa Pharma Corporation QINGDAO NESCO MEDICAL CO., LTD. Shikoku Alfresa Corporation (Kagawa Prefecture) Alfresa Corporation (Tokyo) Alfresa Medical Service Corporation (Tokyo) Alfresa Healthcare Corporation (Tokyo) Mogi Pharmaceutical Co., Ltd. (Tokyo) Alfresa Fine Chemical Corporation Koichi Shimada, President and CEO 2-2-9, Koku-machi, Chuo-ku, Osaka, Osaka Prefecture Manufacturing, import/export and marketing of pharmaceuticals, diagnostic reagents, medical devices, and materials for pharmaceuticals, Akihiko Miyadera, President and CEO , Mukaihama, Akita, Akita Prefecture Manufacturing of active pharmaceutical ingredients Sannova Co., Ltd. Takahiro Sakamoto, General Manager and CEO No.11 Xinghai Rd., Chengyang, Qingdao, Shandong, China Manufacturing, export and sale of surgical sutures Toru Takekawa, President , Serada-cho, Ota, Gunma Prefecture Research, development, manufacturing and sales of pharmaceuticals and quasi-drugs, Apollo Medical Holdings Inc. (Tokyo) Alfresa System Corporation (Tokyo) Apollo Medical Holdings Inc. Nihon Apoch CO., LTD Teruo Azuma, Chief Executive Officer F, Minamiotsuka, Toshima-ku, Tokyo Dispensing pharmacy business Toshiyuki Tachi, President 6-20, Wakitahoncho, Kawagoe, Saitama Prefecture Dispensing pharmacy business RYUYAKU CO., LTD. (Okinawa Prefecture) Pharmaceuticals Wholesaling Business Self-Medication Products Wholesaling Business Information System Business for the Alfresa Group Information System Business for the Alfresa Group Alfresa System Corporation Masashi Imanari, President 1-1-3, Otemachi, Chiyoda-ku, Tokyo Operation, maintenance and development of information system for the Alfresa Group 7 Corporate Profile 2017 Corporate Profile

6 History of the Alfresa Group Alfresa Corporation partially transfers stocks of Specialty Medical Distribution Corporation to TOMITA Pharmaceutical Co., Ltd. (Kumamoto Prefecture) and Moroo Co., Ltd. (Hokkaido) The pharmaceutical manufacturing and sales business of Sannova Co., Ltd. (Gunma Prefecture), which was a consolidated subsidiary of Eisai Co., Ltd., is taken over and begins its operations as a wholly owned subsidiary of the Company Odashima Limited (Iwate Prefecture) becomes a subsidiary of Fukujin Co., Ltd. Fukujin Co., Ltd., AZWELL Inc., and Taishodo Co., Ltd. (Saitama Prefecture) are reorganized by business field into the company Alfresa Corporation (Tokyo) and the manufacturing company Alfresa Pharma Corporation (Osaka Prefecture) through corporate separation. The Company establishes Alfresa Pip-Tokyo Corporation (Tokyo), which is engaged in the SPD business, jointly with PIP-Tokyo Co., Ltd. (Tokyo) Meisho Co., Ltd. (Ishikawa Prefecture) becomes a wholly owned subsidiary through a stock exchange. Odashima Limited Alfresa Pip-Tokyo Corporation changes its corporate name to Alfresa Medical Service Corporation. Sannova Co., Ltd Nihon Apoch CO., LTD. (Saitama Prefecture) becomes a subsidiary. SEIWA SANGYO CO., LTD. and Tokiwa Yakuhin Co., Ltd. (Yamaguchi Prefecture) are merged into TS Alfresa Corporation. (Hiroshima Prefecture) Alfresa Pharma Corporation takes over the Akita Plant of Daiichi Sankyo Propharma Co., Ltd., and begins operation as Alfresa Fine Chemical Corporation. (Akita Prefecture) 2003 SEIWA SANGYO CO., LTD. (Hiroshima Prefecture) becomes a wholly owned subsidiary through a stock exchange. OKAUCHI KANKODO, Ltd. (Kagawa Prefecture), Kowa Yakuhin Co., Ltd. (Tokushima Prefecture) and DAIWA Pharmaceutical Wholesalers Co., Ltd. (Ehime Prefecture) merge to form Shikoku Alfresa Corporation. (Kagawa Prefecture) On September 29, AZWELL Inc. (Osaka Prefecture) and Fukujin Co., Ltd. (Tokyo) establish Alfresa Holdings Corporation (Tokyo) through stock transfer. Meisho Co., Ltd Alfresa Holdings Corporation Apollo Medical Holdings Inc. (Tokyo) becomes a subsidiary. RYUYAKU CO., LTD. (Okinawa Prefecture) becomes a wholly owned subsidiary through a stock exchange. The Company establishes Alfresa System Corporation (Tokyo), which is engaged in the operation, maintenance and development of information system for the Alfresa Group, jointly with Hitachi, Ltd. (Tokyo) Kowa Pharmaceuticals Co., Ltd. (Fukushima Prefecture) becomes a wholly owned subsidiary through a stock exchange. The Company concludes a basic agreement regarding comprehensive business cooperation with Liaoning Chengda Co., Ltd. (Dalian, Liaoning, China) and ITOCHU Corporation. (Osaka Prefecture) The self-medication products wholesaling business of CS YAKUHIN CO., LTD. (Aichi Prefecture) is integrated with TAMPEI NAKATA CO., LTD., and TAMPEI NAKATA CO., LTD. changes its corporate name to Alfresa Healthcare Corporation. (Tokyo) The Company enters into a business cooperation agreement with ARATA CORPORATION (Chiba Prefecture), NIPPON ACCESS, INC. (Tokyo), CS YAKUHIN CO., LTD. and TAMPEI NAKATA CO., LTD. (Osaka Prefecture) with regard to operations in areas such as marketing, distribution, and business development related to the wholesaling of foods, daily necessities, over-the-counter drugs and other products. TAMPEI NAKATA CO., LTD. (Tokyo) becomes a wholly owned subsidiary through a stock exchange. Alfresa Corporation establishes Specialty Medical Distribution Corporation, which is engaged in the distribution of specialty drugs, The Company establishes Alfresa Codupha Healthcare Vietnam Co., Ltd. (Ho Chi Minh City, Vietnam), which is engaged in import and sale of healthcare-related products, focusing on medical devices and materials, jointly with Codupha. (Ho Chi Minh City, Vietnam) Alfresa Fine Chemical Corporation Shinohara Chemicals Co., Ltd. (Kochi Prefecture) becomes a wholly owned subsidiary through a stock exchange. Shinohara Chemicals Co., Ltd. changes its corporate name to Alfresa Shinohara Chemicals Corporation. Mogi Pharmaceutical Co., Ltd. (Tokyo) becomes a wholly owned subsidiary. Business Segments Pharmaceuticals Wholesaling Business Self-Medication Products Wholesaling Business * Wholesaling Business (former segment) *Company names and locations of head offices are stated as they were at that time. 9 Corporate Profile 2017 Corporate Profile

7 1-1-3, Otemachi, Chiyoda-ku, Tokyo, , Japan Tel: For environmental reasons, this Corporate Profile is printed on FSC -certified paper using UV inks.

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