PROCEEDINGS OF SPIE. Event: SPIE BiOS, 2007, San Jose, California, United States

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PROCEEDINGS OF SPIE SPIEDigitalLibrary.org/conference-proceedings-of-spie Front Matter: Volume 6433 Proceedings of SPIE Proceedings of SPIE, "Front Matter: Volume 6433," Proc. SPIE 6433, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII, 643301 (13 March 2007); doi: 10.1117/12.727422 Event: SPIE BiOS, 2007, San Jose, California, United States

PROGRESS IN BIOMEDICAL OPTICS AND IMAGING Vol. 8, No. 10 Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII Israel Gannot Editor 20 21 January 2007 San Jose, California, USA Sponsored and Published by SPIE The International Society for Optical Engineering Volume 6433 The International Society for Optical Engineering Proceedings of SPIE The International Society for Optical Engineering, 9780819465467, v. 6433 SPIE is an international technical society dedicated to advancing engineering and scientific applications of optical, photonic, imaging, electronic, and optoelectronic technologies.

The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon. Please use the following format to cite material from this book: Author(s), "Title of Paper," in Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications VII, edited by Israel Gannot, Proceedings of SPIE Vol. 6433 (SPIE, Bellingham, WA, 2007) Article CID Number. ISSN 1605-7422 ISBN 9780819465467 Published by SPIE The International Society for Optical Engineering P.O. Box 10, Bellingham, Washington 98227-0010 USA Telephone 1 360/676-3290 (Pacific Time) Fax 1 360/647-1445 http://www.spie.org Copyright 2007, The Society of Photo-Optical Instrumentation Engineers Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at http://www.copyright.com. Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1605-7422/07/$18.00. Printed in the United States of America.

Contents vii Conference Committee SESSION 1 643303 A novel hyperspectral lifetime probe for autofluorescence [6433-01] P. A. A. De Beule, C. Dunsby, D. M. Owen, N. P. Galletly, U. Anand, Imperial College London (United Kingdom); C. D. Benham, A. Naylor, GlaxoSmithKline (United Kingdom); G. W. Stamp, P. Anand, P. M. W. French, Imperial College London (United Kingdom) 643304 Miniature optical fiber pressure microsensors for in vivo measurement of intramuscular pressure [6433-02] P. S. Cottler, D. Blevins, J. Averett, T. A. Wavering, Luna Innovations, Inc. (USA); D. A. Morrow, A. Y. Shin, K. R. Kaufman, Mayo Clinic (USA) 643305 Multispectral therapeutic endoscopy imaging and intervention [6433-03] J. L. Bala, Micro Invasive Technology, Inc. (USA); S. D. Schwaitzberg, Cambridge Health Alliance (USA) 643306 Modification of mid-infrared radiation spatial structure caused by COP/Ag hollow waveguide [6433-04] M. Nĕmec, H. Jelínková, M. Fibrich, P. Koranda, Czech Technical Univ. (Czech Republic); M. Miyagi, K. Iwai, Sendai National College of Technology (Japan); Y.-W. Shi, Fudan Univ. (China); Y. Matsuura, Tohoku Univ. (Japan) 643307 Hollow core photonic crystal fiber surface enhanced Raman probe [6433-05] H. Yan, Tsinghua Univ. (China); C. Gu, Univ. of California, Santa Cruz (USA); C. Yang, J. Liu, G. Jin, J. Zhang, Tsinghua Univ. (China); L. Hou, Yanshan Univ. (China); Y. Yao, Tsinghua Univ. (China) Pagination: Proceedings of SPIE follow an e-first publication model, with papers published first online and then in print and on CD-ROM. Papers are published as they are submitted and meet publication criteria. A unique, consistent, permanent citation identifier (CID) number is assigned to each article at the time of the first publication. Utilization of CIDs allows articles to be fully citable as soon they are published online, and connects the same identifier to all online, print, and electronic versions of the publication. SPIE uses a six-digit CID article numbering system in which: The first four digits correspond to the SPIE volume number. The last two digits indicate publication order within the volume using a Base 36 numbering system employing both numerals and letters. These two-number sets start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B 0Z, followed by 10-1Z, 20-2Z, etc. The CID number appears on each page of the manuscript. The complete citation is used on the first page, and an abbreviated version on subsequent pages. iii

SESSION 2 643308 The influence of fiber s photosensitivity by doping process [6433-07] F. Tu, Huazhong Univ. of Science and Technology (China); Q. Han, J. Luo, Yangtze Optical Fiber and Cable Co. Ltd. (China); D. Liu, Huazhong Univ. of Science and Technology (China) 643309 Study of optical fiber damage under tight bend with high optical power at 2140 nm [6433-08] X. Sun, J. Li, A. Hokansson, OFS (USA) 64330A 64330B Simultaneous delivery of Er:YAG and Ho:YAG lasers by using hollow optical fibers for endoscopic lithotripsy [6433-09] K. Iwai, Sendai National College of Technology (Japan); Y. Matsuura, Tohoku Univ. (Japan); M. Miyagi, Sendai National College of Technology (Japan) Experimental evaluation of angularly variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms [6433-10] A. Wang, V. Nammalvar, R. Drezek, Rice Univ. (USA) SESSION 3 64330D Fiber-optic detection device for GC-UV [6433-12] H. S. Eckhardt, Univ. of Applied Sciences Giessen Friedberg (Germany) and City Univ. London (United Kingdom); H. Dominick, Dominick (Germany); K. T. V. Grattan, City Univ. London (United Kingdom); K. Graubner, K.-F. Klein, Univ. of Applied Sciences Giessen Friedberg (Germany); B. Spangenberg, Univ. of Applied Sciences Offenburg (Germany); T. Sun, City Univ. London (United Kingdom) 64330E 64330F Polymer/metal sulfide coated hollow waveguides for delivery of Er:YAG laser radiation [6433-13] V. S. Johnson, B. Bowden, J. A. Harrington, Rutgers Univ. (USA) New components for fiber-optic thin-layer chromatography including fluorescence [6433-14] M. Bleichert, Univ. of Applied Sciences Offenburg (Germany); H. S. Eckhardt, K.-F. Klein, Univ. of Applied Sciences Giessen Friedberg (Germany); B. Spangenberg, Univ. of Applied Sciences Offenburg (Germany); G. Hillrichs, Univ. of Applied Sciences Merseburg (Germany); J. Mannhardt, J&M Analytische Mess- und Regeltechnik GmbH (Germany) SESSION 4 64330H UV LED fiber optic detection system for DNA and protein [6433-16] M. Belz, World Precision Instruments, Inc. (USA); F. A. Klein, Transmit GmbH (Germany); H. Habhegger, World Precision Instruments, Inc. (USA) 64330K Remote FTIR reflectometry for clinical diagnostic using hollow optical-fiber probe [6433-19] Y. Matsuura, S. Kino, Tohoku Univ. (Japan) iv

SESSION 5 64330L Hollow infrared fiber with an inorganic inner coating layer with high durability [6433-29] K. Iwai, Sendai National College of Technology (Japan); Y.-W. Shi, Fudan Univ. (China); M. Miyagi, Sendai National College of Technology (Japan); X.-S. Zhu, Fudan Univ. (China); Y. Matsuura, Tohoku Univ. (Japan) 64330M Laser induced fluorescence as a diagnostic tool integrated into a scanning fiber endoscope for mouse imaging [6433-20] C. M. Brown, L. Maggio-Price, E. J. Seibel, Univ. of Washington (USA) 64330N Applications of rigid and flexible GRIN-endoscopes [6433-21] S. Schenkl, A. Ehlers, Saarland Univ. (Germany) and Fraunhofer Institute of Biomedical Technology (Germany); I. Riemann, Fraunhofer Institute of Biomedical Technology (Germany); B. Messerschmidt, GrinTech GmbH (Germany); R. Bückle, Jenlab GmbH (Germany); K. König, Saarland Univ. (Germany) and Fraunhofer Institute of Biomedical Technology (Germany) 64330O Hollow fiber-optic Raman probes for small experimental animals [6433-22] T. Katagiri, Y. Hattori, T. Suzuki, RIKEN The Institute of Physical and Chemical Research (Japan); Y. Matsuura, Tohoku Univ. (Japan); H. Sato, RIKEN The Institute of Physical and Chemical Research (Japan) SESSION 6 64330U New tellurium based glasses for use in bio-sensing applications [6433-28] A. Wilhelm, Univ. of Arizona (USA); C. Boussard-Pledel, Lab. des Verre et Céramiques, CNRS, Univ. de Rennes I (France); P. Lucas, M. R. Riley, Univ. of Arizona (USA); B. Bureau, J. Lucas, Lab. des Verre et Céramiques, CNRS, Univ. de Rennes I (France) Author Index v

Conference Committee Symposium Chairs Program Track Chairs James G. Fujimoto, Massachusetts Institute of Technology (USA) R. Rox Anderson, Wellman Center for Photomedicine (USA), Massachusetts General Hospital (USA), and Harvard School of Medicine (USA) Tuan Vo-Dinh, Duke University (USA) Anita Mahadevan-Jansen, Vanderbilt University (USA) Conference Chair Israel Gannot, The George Washington University (USA) and Tel Aviv University (Israel) Program Committee Session Chairs Richard O. Claus, Virginia Polytechnic Institute and State University (USA) Ilko K. Ilev, U.S. Food and Drug Administration (USA) Karl-Friedrich Klein, Fachhochschule Giessen-Friedberg (Germany) Pierre Lucas, The University of Arizona (USA) Yuji Matsuura, Tohoku University (Japan) Session 1 Pierre Lucas, The University of Arizona (USA) Session 2 Israel Gannot, The George Washington University (USA) and Tel Aviv University (Israel) Session 3 Yuji Matsuura, Tohoku University (Japan) Session 4 James A. Harrington, Rutgers University (USA) Session 5 Ilko K. Ilev, U.S. Food and Drug Administration (USA) Session 6 Karl-Friedrich Klein, Fachhochschule Giessen-Friedberg (Germany) vii