High resolution mass spectrometry (HRMS*) in Graz

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1 High resolution mass spectrometry (HRMS*) in Graz as of January 24 th, 2018 * Instruments with high resolution where exact mass measurements can be performed 1

2 HRMS in Graz s and Ionisation Techniques b 4 5a 1b ESI APCI MALDI LDI EI/CI/DCI FD/FI TU Graz - TCVB/EGAM Uni Graz - IMB 1a Meduni Graz - ZMF Meduni Graz - IFM Uni Graz - Chemistry JR - Health 2

3 TU Graz Mass Spectrometry of the Faculty of Technical Chemistry, Chemical and Process Engineering, Biotechnology (MS TCVB) Graz University of Technology MS TCVB, Kopernikusgasse 24/1, 8010 Graz Contact Ao.Univ.-Prof.Dr. Robert Saf Institute of Chemistry and Technology of Materials Stremayrgasse 9, 8010 Graz Phone: , Pure and complex samples from synthetic chemistry, materials science, biomaterials, pharmaceuticals, samples from industrial partners Fast screening and detailed investigations including HRMS measurements, scientific as well as technological investigations Low molecular weight compounds and metall-organics, from gaseous small molecules to complex structures, synthetic oligomers and polymers, composites, bio-molecules and -materials, carbohydrates, Waters GCT Premier HR orthogonal acceleration time-of-flight (oa-tof) MS Electron impact ionisation (EI) Chemical ionisation (CI) Direct chemical ionisation (DCI) Field desorption (FD) Field ionisation (FI) GC (Agilent 7890A) with autosampler Direct insertion probe Micromass TofSpec 2E Linear and HR reflectron time-of-flight (TOF) MS Matrix assisted laser desorption / ionisation (MALDI) Laser desorption / ionisation (LDI) Waters MicroMX Linear and HR reflectron time-of-flight (TOF) MS Matrix assisted laser desorption / ionisation (MALDI) 3

4 TU Graz NAWI Central Laboratory for Water, Minerals and Rocks, Institute of Applied Geosciences (EGAM) Graz University of Technology Institute of Applied Geosciences Rechbauerstraße 12, 8010 Graz Contacts Ass. Prof. Dr. Dorothee Hippler Phone: Ao.Univ. Prof. Dr. Christoph Hauzenberger Phone: Nu Plasma II HR MC-ICP-MS Inlet system DSN-100 for dry plasma mode Agilent 7500cx ICP-MS ESI NWR193 Laser ablation (LA) unit Geo- and environmental sciences, hydrogeochemistry Radiogenic and heavy stable isotopes, environmental proxies and geotracers, U-Pb dating, main and trace element analysis, in-situ analysis via LA-ICP-MS Waters and geomaterials 4

5 KFU Graz Institute of Molecular Biosciences (IMB) Karl Franzens University Graz Institute for Molecular Biosciences (IMB) Humboldtstr. 50/2, 8010 Graz Contact Dr. Gerald Rechberger Institute of Molecular Biosciences Humboldtstr. 50/2, 8010 Graz Phone: Lipid analysis Fast screening and detailed investigations including HRMS measurements, scientific as well as technological investigations All kind of lipid samples and extracts Waters Synapt HDMS HR QTof MS with ion mobility Atmospheric pressure chemical ionisation (APCI) UPLC (Waters Aquity) with autosampler Direct infusion Agilent G6560 IM-Q-TOF (to be installed) HR QTof MS with ion mobility Nano-electrospray ionisation (nano-esi) Agilent 1290 Infinity UHPLC, Agilent 1260 Infinity II SFC 5

6 MUG Institute of Forensic Medicine (IFM) Medical University Graz Institute of Forensic Medicine Universitätsplatz 4/II, 8010 Graz Contact Ao.Univ.-Prof.Dr. Manfred Kollroser Phone: Thermo Scientific Exactive HR Orbitrap MS UHPLC with autosampler, direct infusion Proteomics as well as various forensic applications Fast screening and detailed investigations including HRMS measurements, scientific as well as technological investigations All kind of bio-, medical- and pharmaceutical samples 6

7 MUG Center for Medical Research (ZMF) Medical University Graz Center for Medical Research Stiftingtalstraße 24/1, 8010 Graz Contacts Dr. Harald C. Köfeler Phone: Lipid analysis, Proteomics, biomarker discovery and quantitation, tissue molecular imaging and protein top-down sequencing, Metabolomics Fast screening and detailed investigations including HRMS measurements, scientific as well as technological investigations All kind of bio- and biomedical samples Bruker UltrafleXtreme HR TOF-TOF MS Matrix assisted laser desorption / ionisation (MALDI) Thermo Scientific LTQ Orbitrap HR Orbitrap MS Bruker Maxis HD HR Q-TOF MS Atmospheric pressure chemical ionisation (APCI) Inlet systems UHPLC (Thermo Ultimate 3000), Nano HPLC (Thermo Ultimate 3000) Thermo Q-Exactive Focus HR Orbitrap MS Atmospheric pressure chemical ionisation (APCI) Inlet systems UHPLC (Thermo Vanquish), Nano ESI-Chip (Advion Nanomate) 7

8 KFU Institute of Chemistry - Analytical Chemistry University of Graz Institute of Chemistry - Analytical Chemistry Universitätsplatz 1, 8010 Graz Contacts Assoc. Prof. Mag. Dr. Georg Raber Phone: georg.raber@uni-graz.at Agilent 7500ce ICPMS Inductively coupled argon mass spectrometer Agilent 7900ce ICPMS Inductively coupled argon mass spectrometer Environmental analysis, food analysis, metabolism studies ICPMS (total metal determinations) HPLC-ICPMS (speciation analysis) HPLC-ESMS/MS (speciation analysis) GC-MS and GC-ICPMS Environmental and food samples Agilent 8800ce ICPMS/MS Inductively coupled argon mass spectrometer Agilent 6460a ESMS/MS Agilent 6890/5975c GCMS with autosampler for liquid/headspace/spme injection Electron ionisation (EI) HPLC System Agilent 1100 HPLC with UV and fluorescence detector Agilent 1200 HPLC with UV and fluorescence detector 8

9 KFU Institute of Chemistry-Org. & Bioorg. Chemistry University of Graz Institute of Chemistry - Organic & Bioorganic Chemistry Heinrichstrasse 28, 8010 Graz Contacts Mag. Dr. Sigurd Schober Phone: si.schober@uni-graz.at Agilent 6230 TOF/MS APCI/ESI HPLC System Agilent 1260 HPLC with DAD detector synthetic organic chemistry, renewable resources Oleochemistry, natural products and compounds, biomass derivatives, biofuels Hi-Resolution TOF/MS Natural and synthetic organic compounds with mass ranges up to m/z 9

10 JR - HEALTH Joanneum Research - Health Neue Stiftingtalstraße 2, 8010 Graz Contact Mag. Dr. Christoph Magnes JR HEALTH Bioanalytik und Metabolomics Phone: christoph.magnes@joanneum.at Metabolomics, medical research Fast screening and detailed investigations including HRMS measurements, scientific as well as technological investigations All kind of bio- and biomedical samples Thermo Scientific LTQ Orbitrap HR Orbitrap MS Atmospheric pressure chemical ionisation (APCI) HPLC Thermo Scientific Exactive HR Orbitrap MS HPLC 10