Instrument Cleaning Chemistries Automated Washing Process

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1 Instrument Cleaning Chemistries Automated Washing Process Procedure Pre-cleaning Prolystica Enzymatic Presoak and Cleaner Klenzyme Enzymatic Presoak and Cleaner ZolvStat Multi-Enzymatic Detergent Pre-Klenz Instrument Transport Gel Instrument Reprocessing Questions to Consider 1a. Soaking - what solution and for how long do you typically soak your instruments? 1b. Manual Cleaning - what solution do you use? 1c. Automated Washing - What solution do you use and at what dilution? High Impingement Chemistries 2. What departments are you responsible for cleaning and processing surgical instrumentation? Are there departments which process instruments separately (i.e. ASC, physician offi ces, etc?) Enzyme Treatment Prolystica Ultra Enzyme Prolystica Enzymatic Presoak and Cleaner EnzyCARE 2 Klenzyme Prolystica Ultra Renu-Klenz NpH-Klenz Prolystica Ultra Criti-Klenz Instru-Klenz Liqui-Jet 2 3. What materials do you currently process (, brass,, plastics)? 4. What type of soils are you challenged to clean? (fatty, blood, etc) 5. Have you had any problems with spotting, staining or pitting of your instruments? If so, how did you resolve this situation? 6. If you could describe your ideal instrument process, what would it be? Low Impingement Chemistries High H-Klenz Acid Neutralizing Rinse CA-Klenz Prolystica Ultra e Criti-Klenz Instrument s Prolystica Ultra e Hinge-Free Packaging Sterilization Instrument s Prolystica Ultra te Hinge-Free

2 Product Attributes Prolystica Ultra Name Enzymatic Neutral Alkaline Premium Ultra Dual Protease Enzyme Instrument/Washer Protection System Automated Washer Application Superior Performance in High Impingement Washers Surgical Aluminum brass/ High Impingement Washer Premium Ultra Instrument/Washer Protection System Automated Washer Application Superior Performance in High Impingement Washers Surgical Aluminum brass/ High Impingement Washer Premium Ultra Instrument/Washer Protection System Automated Washer Application Superior Performance in High Impingement Washers on select soft metals Surgical brass/ High Impingement Washer Premium Ultra Instrument designed to keep surgical instruments operating freely and easily Instrument Protection System Surgical Aluminum brass/ Does not interfere with steam sterilization or ETO sterilization Non-cytotoxic at use dilution High Impingement Washer Color Light Straw-Amber Golden Yellow - Amber Golden Yellow - Dark Amber Clear - Slight Yellow ph Foaming Characteristics Low to Unstable Low to Unstable Low to Unstable Low to Unstable Product Number 1C03T4WR/1C03T6WR 1C07T4WR/1C07T6WR 1C12T4WR/1C12T6WR 1C05T4WR/1C05T6WR Sizes 2 x 5 L / 10 L 2 x 5 L / 10 L 2 x 5 L / 10 L 2 x 5 L / 10 L Dosage* 1/40-1/10 oz per gallon 1/40-1/10 oz per gallon 1/40-1/10 oz per gallon 1/40-1/10 oz per gallon s are: > Liquid formulas that are more soluble in water than powders > Compatible with a variety of instrument substrates, including soft metals > Designed to maximize the cleaning performance of your STERIS > Formulated with built-in protection against instrument damage > Effective at dilutions of 1/10-1/40 ounce per gallon > Made with biodegradable chemistries one gallon = ten gallons

3 Product Attributes Name Renu-Klenz High quality neutral ph detergent 2-8 times more concentrated than traditional liquid detergents surgical High impingement Neutral ph Detergents Renu-Klenz NpH-Klenz Criti-Klenz High quality neutral ph detergent surgical stainless High impingement Neutral ph detergent Moderate hard water tolerance surgical stainless High impingement High quality alkaline detergent 2-8 times more concentrated than traditional liquid detergents Superior performance in high impingement 13 Plastics - not compatible with acrylic surgical Not compatible with High or low impingement Presoak Color Colorless - Light straw Light straw Orange to red-orange Orange Orange STERIS Traditional Safe Alkaline Criti-Klenz High quality alkaline detergent Superior performance in high impingement 13 Plastics - not compatible with acrylic surgical Not compatible with High or low impingement Presoak ph Foaming Characteristics Low and short lived Low and unstable Medium and stable Low and short lived Low and unstable Product Number Sizes 15, 5, 2.5, 1 gallon 30, 15, 5, 1 gallon and 30, 15, 5, and 1 gallon 15, 5, 2.5 and 1 gallon 15, 5, and 1 gallon Bag-in-a-box Dosage* 1/8-2 oz/ gallon 1/4-4 oz/ gallon 1/8-2 oz/ gallon 1/4-1 oz/ gallon 1/4-2 oz/ gallon Product Attributes Enzymatic Chemistries Name EnzyCARE 2 Enzymatic Presoak and Cleaner Dual protease enzyme Optimized for use in automated May be used in manual applications surgical stainless Automated ZolvStat Multi-Enzymatic Detergent High quality multi-enzymatic - protease, lipase and amylase Effective against fats, adipose tissues (orthopedics) Appropriate for manual washing applications surgical Not compatible with Klenzyme Enzymatic Presoak and Cleaner High quality single protease enzyme Appropriate for manual washing applications surgical Not compatible with Not compatible with brass Automated Color Deep blue Blue Straw to light amber ph Foaming Characteristics Low and unstable Moderate and stable Moderate and stable Product Number Sizes* 15, 5, and 1 gallon 1 gallon 30, 15, 5, 1 gallon and Bag-in-a-box Dosage* Manual = 1 oz/gallon Automated = 1/4-2 oz/gallon Manual = 1-2 oz/gallon Manual = 1 oz/gallon

4 Chemistries Detergents High Acid Neutralizer Detergent Liqui-Jet 2 Instru-Klenz H-Klenz II C-A Klenz High quality Alkaline detergent Superior performance in high impingement Alkaline detergent Superior performance in high impingement High quality alkaline detergent Superior performance in low impingement High quality acid neutralizer Superior performance in low impingement surgical stainless Not compatible with 13 Plastics - not compatible with acrylic surgical Not compatible with 13 Plastics - not compatible with Buna-N and neoprene surgical Not compatible with brass surgical Not compatible with Not compatible with brass/ High or low impingement High or low impingement Low impingement Customers preferring an alkaline/acid combination Low impingement Customers preferring an alkaline/`acid combination Light yellow Light yellow Light straw Colorless Low and unstable Low and unstable Low and unstable None , 15, 5, and 1 gallon 30, 15, 5, and 1 gallon 15 and 5 gallon 15 and 5 gallon 1/4-2 oz/ gallon 1/8-2 oz/ gallon 1/4-1/2 oz/ gallon Used in a ratio of 0.7 CA Klenz to 1.0 of H-Klenz II Lubrication Chemistries Hinge-Free Instrument High quality instrument lubricant designed to keep surgical instruments operating freely and easily Non-silicone based formula surgical Not compatible with High and low impingement Milk white 7.8 Low and short lived , 5, 1 gallon and Bag-in-a-box Manual = 1 part Hinge Free to 6 parts water Automated = 1/2-2 oz/gallon *Size Designation 1 gal = gal = U9 5 gal = gal = P3 30 gal = 02 *Dosage recommendations are dependent on water quality, soil load and application.

5 Product Attributes Name Prolystica 2X s Enzymatic Presoak and Cleaner Premium 2 Times d Dual Protease Enzyme Instrument/Washer Protection System Manual or Automated Washer Application Superior Performance in High or Low Impingement Washers Surgical Aluminum High Impingement Washers / Ultrasonics / Manual Color Light Straw-Amber ph 7.5 Foaming Characteristics Low to Unstable Product Number 1C3308, 1C3310, 1C3305, 1C33P3 Sizes 4 x 1 Gallon, 2.5 Gallon, 5 Gallon, 15 Gallon Dosage* 1/8-1/2 oz per gallon *Dosage recommendations are dependent on water quality, soil load and application. one gallon = two gallons Prolystica Enzymatic Presoak and Cleaner is engineered to provide enhanced cleaning of fatty orthopedic and protein soils in multiple applications: > Manual cleaning > Endoscopy departments > Sterile processing departments > Automated

6 Instrument Cleaning Chemistries Materials Compatibility ALUMINUM Transportation Trays Enzymatic Prolystica Enzymatic Presoak and Cleaner EnzyCARE 2 Renu-Klenz NpH Klenz Liqui-Jet 2 H-Klenz II Hinge Free BRASS/COPPER Fittings/couplings for piping Enzymatic Prolystica Enzymatic Presoak and Cleaner Klenzyme () EnzyCARE 2 Adi-Zyme ZolvStat Renu-Klenz NpH Klenz Criti-Klenz Instru-Klenz H-Klenz II () PLASTICS Gaskets Peristaltic pump/hosing Tubing PVC Piping Surgical Instruments Enzymatic Prolystica Enzymatic Presoak and Cleaner Klenzyme EnzyCARE 2 ZolvStat Renu-Klenz NpH Klenz Criti-Klenz Instru-Klenz H-Klenz CA-Klenz Hinge Free Prolystica Ultra Cleaning System STERIS OFFICES WORLDWIDE Benelux Japan Canada Korea China Latin America France Malaysia Germany Singapore Greece Spain India Switzerland Italy United Kingdom STERIS Corporation 5960 Heisley Road Mentor, OH USA Document # M2803EN , Rev. D Printed 02/2009, STERIS Corporation. All rights reserved. Printed in USA. Technologies to Prevent Infection and Contamination

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