A Novel Insecticidal Soap for the Control of Soft Bodied Insect Pests

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1 A Novel Insecticidal Soap for the Control of Soft Bodied Insect Pests Dr Owen Jones Business Development Director Naturiol Bangor Ltd 1

2 Naturiol LTD a new spinout company at Bangor University, North Wales High value platform chemicals from indigenous plants. Extracting plant saponins and unusual fatty acids. Research into new products with agricultural applications. Innovate UK biotech plant cell culture project. Another Innovate UK project on modified saponins for anthelmintic applications. 2

Naturiol LTD a new spinout company at Bangor University, North Wales Prof

organic synthesis and bioactive materials from plants.

years of industrial experience in the field of biopesticides.

3 Naturiol LTD a new spinout company at Bangor University, North Wales Prof Mark Baird Retired Professor in organic chemistry with experience in organic synthesis and bioactive materials from plants. Dr Owen Jones 10 Years of experience in academic research and nearly 30 years of industrial experience in the field of biopesticides. Dr Mark Long Recently completed a PhD in synthetic carbohydrate chemistry, with experience in horticulture. 3

Control of Soft-Bodied Insect Pests Current

concentrate for professional use and as a

Effective against aphids, mealybugs, spider

Sprayed directly onto insects, quickly killing

No known effect on bees, pollinators, and

Compatible with biological controls, such as

4 Control of Soft-Bodied Insect Pests Current Insecticidal Soap Solutions Available as a concentrate for professional use and as a ready to use product for home and garden. Effective against aphids, mealybugs, spider mites, thrips and whiteflies. Sprayed directly onto insects, quickly killing on contact by destroying the cuticle. No known effect on bees, pollinators, and predatory insects. Low mammalian toxicity. Compatible with biological controls, such as predators and parasites, microbial pesticides, and semiochemicals, certified for organic use. 4

Control of Soft-Bodied Insect Pests Drawbacks to current products Concentrations above 2% can have

Some plants very susceptible to scorching by insecticidal soaps such as Brassicas, cucumbers and

At 6% can cause severe phytotoxicity in ornamental plants such as Gardenia, Lantana, poinsettia,

5 Control of Soft-Bodied Insect Pests Drawbacks to current products Concentrations above 2% can have phytotoxic effects, especially with multiple applications. Some plants very susceptible to scorching by insecticidal soaps such as Brassicas, cucumbers and certain ornamentals. At 6% can cause severe phytotoxicity in ornamental plants such as Gardenia, Lantana, poinsettia, Begonia and Impatiens. Soaps are widely used in home and garden, but commercial growers are reluctant to use them at concentrations that give good control of pests fearing some cosmetic damage to their produce from phytotoxicity. 5

Our product: A novel insecticidal soap, again

reduced phytotoxicity and with improved efficacy

6 Our product: A novel insecticidal soap, again based on fatty acids but formulated to have reduced phytotoxicity and with improved efficacy against insects that are not well controlled by soaps. Equal or better efficacy than traditional solutions. Shown in trials to be effective against plant hoppers, glasshouse potato aphids, green peach aphids, red spider mites, thrips, whiteflies and mealy bugs 6

7 Mealy bug before and after treatment with Naturiol Soap Shows the wax stripping ability on these difficult to control insects Before treatment After treatment 7

8 Whitefly Tests Underside of aubergine leaf treated with Naturiol at 4% (2% FAs) 8

9 Whitefly Tests Underside of aubergine leaf - untreated control owenjones@naturiol.eu 9

10 Floor covered with black plastic below aubergine plants treated with Naturiol at 4% (2% Fas) and control Treated Control 10

Efficacy % Independent Efficacy tests 100 90 80 70 60 50 40 30 20 10 0 Aphids Thrips Spider mite Whitefly Naturiol Insecticidal Soap Soap Commercial

11 Efficacy % Independent Efficacy tests Aphids Thrips Spider mite Whitefly Naturiol Insecticidal Soap Soap Commercial Standard Conventional Agrochemical Standard Address: Naturiol Bangor Ltd, Alun Roberts Building, School of Chemistry, Bangor University, Bangor, UK, LL57 2UW 11

carrots, courgettes, lettuce, melon, Swiss chard, spinach, sweet peppers or tomatoes.

12 Our product: banana tests At 4%, 6% or 10% concentration the new soap product was not phytotoxic to the following vegetables and fruits: Bananas, beans, broccoli, Brussels sprouts, cabbage, cauliflower, carrots, courgettes, lettuce, melon, Swiss chard, spinach, sweet peppers or tomatoes. Nor was it phytotoxic at these concentrations to the following ornamentals: Lantana, Impatiens or the orchid Phalaenopsis amabilis 2% 6% 12

Significant damage to plants treated with the standard and only very small levels of leaf

13 A comparison of damage in tomato seedlings sprayed twice with a standard commercial soap and Naturiol Soap at 6%. Significant damage to plants treated with the standard and only very small levels of leaf deformation with Naturiol. Tomato seedlings treated with Commercial Soap Standard 6% (top), Naturiol 6% (bottom left) and a water control (bottom right).

14 IPR, Patents and Regulatory The IP belongs to Naturiol Bangor Ltd Initial search by UK patent office has shown no competing patents and that there is freedom to operate Patenting process entered the PCT stage in September 2016 Regulatory aspects are being addressed in various geographies 14

15 We are looking for exploitation partners in different geographies and market sectors Professional markets Home and garden 15

16 Thank you for your kind attention. 16

A Novel Insecticidal Soap for the Control of Soft Bodied Insect Pests

A Novel Insecticidal Soap for the Control of Soft Bodied Insect Pests Owen Jones Biopesticides Conference Swansea University September 2015 Address: Naturiol Bangor Ltd, Alun Roberts Building, School of