2010 International Conference on Biocontainment

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1 2010 International Conference on Biocontainment Tradeline Conference Series 10 CRITICAL DETAILS to Make Gaseous or Vapor Decontamination Systems Successful Forum Session J March 25 th and 26 th, 2010 Lloyd E.L. Fisk, AIA LEED AP Paul Lemestre, P.E., LEED AP, MBA Research Facilities Design

2 PRESENTATION OUTLINE 1. Agent Comparisons 2. Local Delivery Systems Please ask questions as you think of them 3. Central Distributed Delivery Syste ems 4. Casework Systems 5. Room Finishes and Materials 6. Sealing the Room: The Door 7. Sealing the Room: HVAC Ducts 8. Using Premanufactured Chambers 9. HVAC: Design 10. HVAC: Controls

3 1. AGENT COMPARISONS FORMALDEHYDE VHP CLO2 FORM AT USE GAS VAPOR GAS OSHA PEL 0.75 PPM 1.0 PPM 0.1 PPM CONCENTRATION AT USE CYCLE TIME 8000 PPM 12 + HOURS PPM 360 PPM 4-12 HOURS 3-4 HOURS ENGINEERED LOCAL SYSTEMS NOT POSSIBLE/ AVAILABLE YES YES DISTRIBUTION LIMITATIONS (CENTRAL SYSTEMS) NOT POSSIBLE 300 FEET 500 FEET

4 2. LOCAL DELIVERY SYSTEMS

5 2. LOCAL DELIVERY SYSTEMS

6 2. LOCAL DELIVERY SYSTEMS

7 2. LOCAL DELIVERY SYSTEMS Thanks Steve Crowley CLO2

8 2. LOCAL DELIVERY SYSTEMS CLO2 VHP

9 2. LOCAL DELIVERY SYSTEMS VHP CLO2

10 2. LOCAL DELIVERY SYSTEMS PROS: Simple (or No) Installation Minimize Points of Failure Flexibility in Agent Use CONS: Cumbersome to Move Unit Out of Containment Either: Unit Occupies Floor Space in Corridor Unit is Run in Room Consumables Brought Into and Out Of Containment

11 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS

12 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS

13 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS CLO2 4 Kynar Tubes 3/8 ¼

14 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS VHP (1) CPVC/PVC PIPE Insulated Size: 2 4

15 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS

16 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS

17 3. CENTRAL DISTRIBUTED DELIVERY SYSTEMS PROS: Unit Outside Containment Can Potentially Be Used Elsewhere (CLO2) Consumables Outside Containm ment No Floor Space Used in Facility CONS: Installation Cost More Points of Failure Agent Specific

18 4. CASEWORK SYSTEMS CONVENTIONAL FIXED CASEWORK Acceptable Difficult to Validate

19 4. CASEWORK SYSTEMS CONVENTIONAL FIXED CASEWORK Acceptable Difficult to Validate BEST PRACTICE: Minimize Fixed Components Minimize Double Wall Construction Minimize Concealed Chases

20 5. ROOM FINISHES AND MATERIALS CONVENTIONAL BSL3 FINISHES Walls Epoxy Painted FRE Floors Seamless Vinyl Epoxy Resin Ceilings GWB, Epoxy Painted Penetrations Sealed Electrical Back Boxes Light Fixtures Piping Fixtures

21 5. ROOM FINISHES AND MATERIALS Consider Higher-Performance Finishes in Dedicated Pass-Thru Rooms Powder-Coated d Steel Wall Panels FRP Wall Systems Stainless Steel Wall Panels

22 5. ROOM FINISHES AND MATERIALS CONVENTIONAL BSL3 FINISHES TWO WEAK POINTS: Door HVAC System

23 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR Close and Tape

24 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR Close and Tape Closers Are Challenging

25 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR Close and Tape Closers Are Challenging

26 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR 2. SEALED DOOR 1. Compression Gasketed

27 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR 2. SEALED DOOR 1. Compression Gasketed

28 6. SEALING THE ROOM: THE DOOR APPROACHES: 1. CONVENTIONAL DOOR 2. SEALED DOOR 1. Compression Gasketed 2. Compressed-Air Sealed

29 7. SEALING THE ROOM: HVAC DUCTS ISOLATION DAMPERS: Bubble tight / leak tight Manual operation Automatic operation PROS: Permanent installation for frequent / semi-frequent operation Allows use of installed HVAC systems to purge room for re-entrance. LEAK-TIGHT ISOLATION DAMPER CONS: Installed costs BSC LEAK-TIGHT ISOLATION DAMPER LABORATORY ROOM BSC

30 7. SEALING THE ROOM: HVAC DUCTS SEALING DIFFUSER AND GRIL LLES: Duct tape / painters tape Vaporproof p covering g( (Visqueen n) PROS: No additional upfront costs CONS: Cumbersome, labor intensive i Requires positive shutoff for HVAC supply and exhaust Potential failure of seal Does not allow use of installed HVAC systems to purge room require es carbon scrubber (ClO2) or catalytic convertor (VHP) to purge space LABORATORY ROOM BSC

31 8. USING PREMANUFACTURED CHAMBERS TYPES: 1. Dedicated Pass-Through Decontamination Chamber 2. Decontamination Compatible Rackwashers 3. Decontamination Compatible Autoclaves GENERATION OPTIONS: 1. Int tegrated Dedicated Generator 2. Ports for Local Generator 3. Co onnection to Distributed System

32 8. USING PREMANUFACTURED CHAMBERS PROS: 1. Engineered to Optimize Cycle Time 2. Turnkey Solution a) b) c) d) Fewer Construction Issues Pneumatically Gasketed Door Integrated Controls Greater Reliability CONS: 1. Limited Sizes 2. Substantial Cost

33 9. HVAC: DESIGN CONSIDERATIONS AIR-HANDLING UNIT EXHAUST FAN UNIT EXHAUST HEPA BANK AIR VALVE TERMINAL WITH COATING STAINLESS STEEL REHEAT COIL HEADERS STAINLESS STEEL DUCTWORK LEAK-TIGHT ISOLATION DAMPER DOOR LABORATORY ROOM STAINLESS STEEL AIR DISTRIBUTION HVAC LOCAL CONTROL SWITCH

34 9. HVAC: DESIGN CONSIDERATIONS VHP CENTRAL SYSTEMS AIR-HANDLING UNIT EXHAUST FAN UNIT EXHAUST HEPA BANK CENTRAL DECON EQUIPMENT DOOR DECON VESTIBULE

35 10. HVAC: CONTROLS AIR-HANDLING UNIT EXHAUST FAN UNIT EXHAUST HEPA BANK LAB CONTROLLER DOOR LABORATORY ROOM HVAC LOCAL CONTROL SWITCH

36 10. HVAC: CONTROLS CENTRAL SYSTEMS AIR-HANDLING UNIT EXHAUST FAN UNIT EXHAUST HEPA BANK LAB CONTROLLER HVAC REMOTE CONTROL SWITCH CENTRAL DECON EQUIPMENT DOOR DECON VESTIBULE HVAC LOCAL CONTROL SWITCH

37 THE TRADELINE THREE KEY DESIGN-PHASE DECISIONS: 1. Local System Versus Central Distributed System 2. Distributed System: Select an Agent 3. Esse ential Infrastructure Must Be Included in Design a) Distributed Systems: Distribution Network HVAC Controls Gasketed Doors at Pass-Thru Room b) Local Systems Ports HVAC Controls Gasketed Doors at Pass-Thru Room 3965 Fifth Avenue, Suite 400 San Diego, California (619)

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